Results 161 to 170 of about 14,885 (290)

Short‐Term 6PPD‐Q Exposure alters Tight‐Junction‐Related Gene Expression Without Acute Lethality in Japanese Medaka Oryzias latipes

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT 6PPD‐quinone (6PPD‐Q), a transformation product of the tire antioxidant 6PPD, causes acute mortality in several salmonid species, but its toxicity varies markedly among fish species. Disruption of vascular‐barrier integrity and inflammatory signaling has been proposed as a key mechanism of 6PPD‐Q toxicity.
Kyoshiro Hiki
wiley   +1 more source

CK8/18 and Claudin Profile of Female Breast Cancers from Botswana. [PDF]

open access: yesBreast Cancer (Auckl)
Ndlovu AK   +3 more
europepmc   +1 more source

Probiotics and intestinal permeability in adults with metabolic dysfunction‐associated steatohepatitis: A secondary analysis of a randomized clinical trial

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is associated with altered intestinal permeability, allowing microbial products to translocate to the liver via the enterohepatic circulation and contributes to disease progression. The aim of our study was to evaluate the association between probiotic supplementation and serum
Bruna Concheski de Moura   +10 more
wiley   +1 more source

Integrated transcriptomic and functional characterization of Claudin-1 reveals its oncogenic and immunomodulatory roles in pancreatic ductal adenocarcinoma. [PDF]

open access: yesTissue Barriers
Surendranath A   +14 more
europepmc   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Nanoscopic analysis of tight junction organization in in vitro blood-brain barrier models. [PDF]

open access: yesFluids Barriers CNS
Waldow A   +4 more
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

open access: yesMed Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng   +14 more
wiley   +1 more source

Claudins proteins in brain tumors: expression patterns and therapeutic target. [PDF]

open access: yesBiochem Med (Zagreb)
Romanowicz A   +2 more
europepmc   +1 more source

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