Results 41 to 50 of about 1,676,547 (251)
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Analysis of dynamic characteristics for momentum wheel assembly with joint clearance
Advances in Mechanical Engineering, 2018 To study the effects of joint clearance on the dynamic characteristics of the momentum wheel assembly of satellite antennas, the computational dynamic model of momentum wheel assembly is developed in this article, considering influencing factors ...
Qi Wan +4 more
doaj +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Jixie chuandong, 2012 The solid model of the system of double cardan joint is built through Pro/Engineer,then it is imported into ADAMS to take the dynamic simulation analysis.For the model which does not contain joint clearance,the proper restrain is added according to ...
张辉, 葛文杰, 宁方立, 赵炜
doaj
Shock and Vibration, 2013 5-DOF dynamic model of vehicle shimmy system with clearance in universal joint of steering handling mechanism is presented. The sub model of cross shaft universal joint with clearance is built based on Hertz' theory, and two-state model is applied to ...
Jianwei Lu +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
The value of statistical life and cost-benefit evaluations of landmine clearance in Cambodia [PDF]
, 2008 Development agencies spend approximately US$400 million per year on landmine clearance. Yet many cost-benefit evaluations suggest that landmine clearance is socially wasteful because costs appear to far outweigh social benefits.
Helmers, Kent +5 more
core
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Large Tip Clearance Flows in High Pressure Stages of Axial Compressors [PDF]
, 2009 This thesis investigates over tip leakage where the tip clearance is large. In the high pressure stages of axial compressors the tip clearance can be typically 6% of span and the total blockage due to tip clearance can consume in excess of forty percent ...
WILLIAMS, RICHARD,JAMES
core