Results 111 to 120 of about 4,811 (202)
Extracellular Paracoccidioides brasiliensis phospholipase B involvement in alveolar macrophage interaction [PDF]
, 2010 Background: Phospholipase B (PLB) has been reported to be one of the virulence factors for human pathogenic fungi and has also been described as necessary for the early events in infection.
Andrade, Rosângela Vieira de +5 more
core +4 more sources
Host Transcriptomics Reveal Reduction in Defence‐Reproduction Trade‐Offs During Coinfection
Molecular Ecology, Volume 34, Issue 21, November 2025.ABSTRACT During infection, hosts may shift resources away from reproduction towards immune defence. It is unclear to what degree these costly trade‐offs can be alleviated during protective coinfections, whereby antagonism between parasites reduces disease severity. We used transcriptomics to assess the extent to which host gene expression reflected the
Ian Will +3 more
wiley +1 more source
Toxins, 2013 The snake venom, rhodocytin, from the Malayan viper, Calloselasma rhodostoma, and the endogenous podoplanin are identified as ligands for the C-type lectin-like receptor 2 (CLEC-2).
Øyvind Bruserud
doaj +1 more source
A role of platelet C-type lectin-like receptor-2 and its ligand podoplanin in vascular biology [PDF]
Purpose of review Platelets are essential for hemostasis and are also vital in lymphatic and lung development and the maintenance of vascular integrity.
20710362 +5 more
core +1 more source
Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators [PDF]
, 2015 Nucleotide-based drug candidates such as antisense oligonucleotides, aptamers, immunoreceptor-activating nucleotides, or (anti)microRNAs hold great therapeutic promise for many human diseases.
Advani +44 more
core +3 more sources
Germinal center formation is resilient to CD69 deletion on T follicular helper cells
Immunology &Cell Biology, Volume 103, Issue 9, Page 844-856, October 2025.CD69 is upregulated on human and mouse CD4+ T follicular helper (TFH) cells within the germinal center. In this article, we use an Il21‐cre mouse strain to ablate floxed Cd69 genes from TFH cells and a proportion of their precursors. We find that when TFH cells lack CD69, the germinal center response remains intact, supporting B‐cell affinity ...
Stephane M Guillaume +6 more
wiley +1 more source
Об одном из частных вопросов преподавания на кафедре гистологии, цитологии и эмбриологии механизма миграции лимфоцитов через посткапиллярные венулы с высоким эндотелием [PDF]
, 2016 методика преподаванияпреподаваниепедагогические технологиигистология /обучкафедра гистологии, цитологии и эмбриологииЦИТОЛОГИЯ /обучЭМБРИОЛОГИЯ ...
Грушин, В. Н. +3 more
core
Cancer Medicine, Volume 14, Issue 18, September 2025.Targeting Cancer associated thrombosis (CAT): The left panel (A) shows cancer‐associated thrombosis with activated platelets expressing αIIbβ3 in close contact with tumoral vasculature expressing αvβ3 integrin, where both cells release a significant amount of thrombin.
Mehran Ghasemzadeh +4 more
wiley +1 more source
Lactate and Lactylation in AKI‐to‐CKD: Epigenetic Regulation and Therapeutic Opportunities
Cell Proliferation, Volume 58, Issue 9, September 2025.ABSTRACT Lactate is not only a byproduct of glycolysis, but is also considered an energy source, gluconeogenic precursor, signalling molecule and protein modifier during the process of cellular metabolism. The discovery of lactylation reveals the multifaceted functions of lactate in cellular metabolism and opens new avenues for lactate‐related research.
Yi Hou +7 more
wiley +1 more source
Advanced Science, Volume 12, Issue 30, August 14, 2025.LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li +8 more
wiley +1 more source