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Click Chemistry in Polymersome Technology [PDF]
PharmaceuticalsPolymersomes, self-assembled nanoparticles composed of amphiphilic block copolymers, have emerged as promising versatile nanovesicles with various applications, such as drug delivery, medical imaging, and diagnostics.
Nuno M. Saraiva +3 more
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Click Chemistry-Based Hydrogels for Tissue Engineering [PDF]
GelsClick chemistry has become a powerful and flexible approach for designing hydrogels used in tissue engineering thanks to its high specificity, fast reaction rates, and compatibility with biological systems.
Soheil Sojdeh +4 more
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From Micro to Marvel: Unleashing the Full Potential of Click Chemistry with Micromachine Integration [PDF]
MicromachinesMicromachines, small-scale engineered devices prepared to carry out exact tasks at the micro level, have garnered great interest across different fields such as drug delivery, chemical synthesis, and biomedical applications.
Zihan Chen +3 more
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Fluorophore-Assisted Click Chemistry through Copper(I) Complexation [PDF]
Biomolecules, 2020 The copper-catalyzed alkyne-azide cycloaddition (CuAAC) is one of the most powerful chemical strategies for selective fluorescent labeling of biomolecules in in vitro or biological systems. In order to accelerate the ligation process and ensure efficient
Victor Flon +5 more
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AutoClickChem: click chemistry in silico. [PDF]
PLoS Computational Biology, 2012 Academic researchers and many in industry often lack the financial resources available to scientists working in "big pharma." High costs include those associated with high-throughput screening and chemical synthesis. In order to address these challenges,
Jacob D Durrant, J Andrew McCammon
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Click Reactions in Medicinal Chemistry
Pharmaceuticals, 2023 Two decades after K [...]
Damien Bosc
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Click chemistry and drug delivery: A bird's-eye view
Acta Pharmaceutica Sinica B, 2023 Click chemistry has been proven to be very useful in drug delivery. Due to the availability of a large number of click reactions with a various characteristics, selection of appropriate chemistry for a given application is often not a trivial task.
Shameer M. Kondengadan +5 more
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Heterogeneous Photocatalytic Click Chemistry [PDF]
Journal of the American Chemical Society, 2016 Copper-doped semiconductors are designed to photoassist the alkyne-azide cycloaddition catalysis by Cu(I). Upon irradiation, injection of electrons from the semiconductor into copper oxide nanostructures produces the catalytic Cu(I) species. The new catalysts are air- and moisture-tolerant and can be readily recovered after use and reused several times.
Wang, Bowen +4 more
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Molecules, 2021 The click azide = alkyne 1,3-dipolar cycloaddition (click chemistry) has become the approach of choice for bioconjugations in medicinal chemistry, providing facile reaction conditions amenable to both small and biological molecules.
Daniela Perrone +3 more
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Biocompatible nanoreactors of catalase and nanozymes for anticancer therapeutics
Nano Select, 2021 Significant progress has laid the groundwork in understanding the fundamental role of catalase enzyme and catalase‐like nanozymes, notably with the emergence of nano‐bioreactors which are promoting nanomaterials‐based antitumor therapeutic strategies ...
Tanya Munjal, Saikat Dutta
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