Results 1 to 10 of about 203,090 (138)

Click Chemistry in Polymersome Technology [PDF]

open access: yesPharmaceuticals
Polymersomes, self-assembled nanoparticles composed of amphiphilic block copolymers, have emerged as promising versatile nanovesicles with various applications, such as drug delivery, medical imaging, and diagnostics.
Nuno M. Saraiva   +3 more
doaj   +4 more sources

Click Chemistry-Based Hydrogels for Tissue Engineering [PDF]

open access: yesGels
Click chemistry has become a powerful and flexible approach for designing hydrogels used in tissue engineering thanks to its high specificity, fast reaction rates, and compatibility with biological systems.
Soheil Sojdeh   +4 more
doaj   +2 more sources

From Micro to Marvel: Unleashing the Full Potential of Click Chemistry with Micromachine Integration [PDF]

open access: yesMicromachines
Micromachines, small-scale engineered devices prepared to carry out exact tasks at the micro level, have garnered great interest across different fields such as drug delivery, chemical synthesis, and biomedical applications.
Zihan Chen   +3 more
doaj   +2 more sources

AutoClickChem: click chemistry in silico. [PDF]

open access: yesPLoS Computational Biology, 2012
Academic researchers and many in industry often lack the financial resources available to scientists working in "big pharma." High costs include those associated with high-throughput screening and chemical synthesis. In order to address these challenges,
Jacob D Durrant, J Andrew McCammon
doaj   +4 more sources

Click Reactions in Medicinal Chemistry

open access: yesPharmaceuticals, 2023
Two decades after K [...]
Damien Bosc
doaj   +3 more sources

Click chemistry and drug delivery: A bird's-eye view

open access: yesActa Pharmaceutica Sinica B, 2023
Click chemistry has been proven to be very useful in drug delivery. Due to the availability of a large number of click reactions with a various characteristics, selection of appropriate chemistry for a given application is often not a trivial task.
Shameer M. Kondengadan   +5 more
doaj   +1 more source

Heterogeneous Photocatalytic Click Chemistry [PDF]

open access: yesJournal of the American Chemical Society, 2016
Copper-doped semiconductors are designed to photoassist the alkyne-azide cycloaddition catalysis by Cu(I). Upon irradiation, injection of electrons from the semiconductor into copper oxide nanostructures produces the catalytic Cu(I) species. The new catalysts are air- and moisture-tolerant and can be readily recovered after use and reused several times.
Wang, Bowen   +4 more
openaire   +3 more sources

Modified Nucleosides, Nucleotides and Nucleic Acids via Click Azide-Alkyne Cycloaddition for Pharmacological Applications

open access: yesMolecules, 2021
The click azide = alkyne 1,3-dipolar cycloaddition (click chemistry) has become the approach of choice for bioconjugations in medicinal chemistry, providing facile reaction conditions amenable to both small and biological molecules.
Daniela Perrone   +3 more
doaj   +1 more source

Enhanced protein–protein interaction network construction promoted by in vivo cross-linking with acid-cleavable click-chemistry enrichment

open access: yesFrontiers in Chemistry, 2022
Chemical cross-linking coupled with mass spectrometry has emerged as a powerful strategy which enables global profiling of protein interactome with direct interaction interfaces in complex biological systems.
Lili Zhao   +13 more
doaj   +1 more source

Biocompatible nanoreactors of catalase and nanozymes for anticancer therapeutics

open access: yesNano Select, 2021
Significant progress has laid the groundwork in understanding the fundamental role of catalase enzyme and catalase‐like nanozymes, notably with the emergence of nano‐bioreactors which are promoting nanomaterials‐based antitumor therapeutic strategies ...
Tanya Munjal, Saikat Dutta
doaj   +1 more source

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