Click Chemistry: Diverse Chemical Function from a Few Good Reactions [PDF]
Angewandte Chemie, 2001 Examination of nature's favorite molecules reveals a striking preference for making carbon-heteroatom bonds over carbon-carbon bonds-surely no surprise given that carbon dioxide is nature's starting material and that most reactions are performed in water.
Hartmuth C. Kolb +2 more
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Click chemistry approaches for developing carbonic anhydrase inhibitors and their applications
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 Click chemistry reactions constitute an important and relatively new approach in the medicinal chemistry toolbox and offer substantial advantages to medicinal chemists in terms of overcoming the limitations of facile chemical synthesis, increased ...
Andrea Angeli, Claudiu T. Supuran
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Click Chemistry and Radiochemistry: An Update. [PDF]
Bioconjug Chem, 2023 The term “click chemistry” describes a class of organic transformations that were developed to make chemical synthesis simpler and easier, in essence allowing chemists to combine molecular subunits as if they were puzzle pieces.
Bauer D +4 more
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From Micro to Marvel: Unleashing the Full Potential of Click Chemistry with Micromachine Integration [PDF]
MicromachinesMicromachines, small-scale engineered devices prepared to carry out exact tasks at the micro level, have garnered great interest across different fields such as drug delivery, chemical synthesis, and biomedical applications.
Zihan Chen +3 more
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Click Chemistry: Reaction Rates and Their Suitability for Biomedical Applications. [PDF]
Bioconjug ChemClick chemistry has become a commonly used synthetic method due to the simplicity, efficiency, and high selectivity of this class of chemical reactions. Since their initial discovery, further click chemistry methods have been identified and added to the ...
Luu T, Gristwood K, Knight JC, Jörg M.
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Innovative Peptide Bioconjugation Chemistry with Radionuclides: Beyond Classical Click Chemistry [PDF]
PharmaceuticalsBackground: The incorporation of radionuclides into peptides and larger biomolecules requires efficient and sometimes biorthogonal reaction conditions, to which click chemistry provides a convenient approach.
Samantha Leier, Frank Wuest
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Applications of Click Chemistry in Radiopharmaceutical Development [PDF]
CHIMIA, 2010 Click chemistry, a concept that employs only practical and reliable transformations for compound synthesis, has made a significant impact in several areas of chemistry, including material sciences and drug discovery.
Joseph C. Walsh, Hartmuth C. Kolb
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Click Chemistry in Natural Product Modification
Frontiers in Chemistry, 2021 Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the molecular diversity and unique functions of complex natural products up to now.
Xiang Zhang +5 more
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Click Chemistry in Polymersome Technology [PDF]
PharmaceuticalsPolymersomes, self-assembled nanoparticles composed of amphiphilic block copolymers, have emerged as promising versatile nanovesicles with various applications, such as drug delivery, medical imaging, and diagnostics.
Nuno M. Saraiva +3 more
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Click Chemistry for the Synthesis of RGD-Containing Integrin Ligands [PDF]
Molecules, 2010 In the last few years click chemistry reactions, and in particular coppercatalyzed cycloadditions, have been used intensively for the preparation of new bioconjugate molecules and materials applicable to biomedical and pharmaceutical areas.
Matteo Colombo, Aldo Bianchi
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