Results 251 to 260 of about 328,516 (352)

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Integrating PLOR and SPAAC Click Chemistry for Efficient Site-Specific Fluorescent Labeling of RNA. [PDF]

Int J Mol Sci
Xue Y, Si X, Yin D, Zhang S, Dai H.
europepmc   +1 more source

Synthesis of an O-alkynyl-chitosan and its chemoselective conjugation with a PEG-like amino-azide through click chemistry [PDF]

, 2011
José Ricardo Oliveira, M. Cristina L. Martins, Luís Mafra, Paula Gomes   +3 more
openalex   +1 more source

Manganese‐Catalyzed Electrochemical Diazidation of Dehydroalanine Peptides

Advanced Science, EarlyView.
A Mn(II)‐catalyzed electrochemical method achieves site‐selective diazidation of dehydroalanine peptides with NaN₃. This radical relay process tolerates diverse functional groups, delivers high yields, and enables precise peptide modification, offering a powerful tool for bioconjugation and therapeutic development.
Xinwei Hu, Chengwei Zheng, Xiaotong Song, Balati Hasimujiang, Mu Chen, Zhixiong Ruan   +5 more
wiley   +1 more source

inCu-click: DNA-enhanced ligand enables live-cell, intracellular click chemistry reaction with copper catalyst. [PDF]

Nat Commun
Nian K, Liu Y, Qiu Y, Zhang Z, Brigandi L, Wanunu M, Rouhanifard SH.   +6 more
europepmc   +1 more source

Strain-Promoted “Click” Chemistry for Terminal Labeling of DNA [PDF]

, 2011
Isaac Marks, Jun Sung Kang, Brady T. Jones, Kevin J. Landmark, A. J. Cleland, T. Andrew Taton   +5 more
openalex   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

Efficient and Selective Biosynthesis of a Precursor-Directed FK506 Analogue: Paving the Way for Click Chemistry. [PDF]

J Nat Prod
Goranovič D, Jenko B, Ramšak B, Podgoršek Berke A, Bedrač L, Horvat J, Šala M, Makuc D, Carriche GM, Silva L, Lopez Krol A, Pšeničnik A, Durán Alonso MB, Avbelj M, Stavber S, Plavec J, Sparwasser T, Müller R, Kosec G, Fujs Š, Petković H.   +20 more
europepmc   +1 more source

A “click chemistry” approach to the straightforward synthesis of new 4-aryl-1,2,3-triazolocarbanucleosides

, 2009
Isabel Pérez-Castro, Olga Caamaño, Franco Fernández, Marcos D. García, Carmen López, Erik De Clercq   +5 more
openalex   +2 more sources

Biofunctional Silicon Nanoparticles by Means of Thiol‐Ene Click Chemistry [PDF]

, 2011
L. Ruizendaal, Sidharam P. Pujari, Veronique S. Gevaerts, Jos M. J. Paulusse, Han Zuilhof   +4 more
openalex   +1 more source