Results 21 to 30 of about 1,290,910 (349)
Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy [PDF]
, 2013 Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer ...
Chan, Kiat-Hwa +8 more
core +1 more source
Click Chemistry in Materials Science [PDF]
, 2014 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106803/1/adfm201302847 ...
Bowman, Christopher N. +3 more
core +1 more source
Click Chemistry in Proteomic Investigations [PDF]
Cell, 2020 Despite advances in genetic and proteomic techniques, a complete portrait of the proteome and its complement of dynamic interactions and modifications remains a lofty, and as of yet, unrealized, objective. Specifically, traditional biological and analytical approaches have not been able to address key questions relating to the interactions of proteins ...
Christopher G. Parker, Matthew R. Pratt
semanticscholar +4 more sources
Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry [PDF]
, 2013 Modern combinatorial chemistry is used to discover compounds with desired function by an alternative strategy, in which the biological target is directly involved in the choice of ligands assembled from a pool of smaller fragments. Herein, we present the
Anna Lucia Fallacara +11 more
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Triazolinediones as highly enabling synthetic tools [PDF]
, 2016 Triazolinediones (TADs) are unique reagents in organic synthesis that have also found wide applications in different research disciplines, in spite of their somewhat "exotic" reputation.
Billiet, Stijn +5 more
core +1 more source
A Not-So-Ancient Grease History: Click Chemistry and Protein Lipid Modifications.
Chemical Reviews, 2021 Protein lipid modification involves the attachment of hydrophobic groups to proteins via ester, thioester, amide, or thioether linkages. In this review, the specific click chemical reactions that have been employed to study protein lipid modification and
K. Suazo, K. Park, M. Distefano
semanticscholar +1 more source
Nanoplasmonics tuned “click chemistry” [PDF]
Nanoscale, 2016 Nanoplasmonics is a growing field of optical condensed matter science dedicated to optical phenomena at the nanoscale level in metal systems. Extensive research on noble metallic nanoparticles (NPs) has emerged within the last two decades due to their ability to keep the optical energy concentrated in the vicinity of NPs, in particular, the ability to ...
Tijunelyte, I. +6 more
openaire +4 more sources
Accelerated SuFEx Click Chemistry For Modular Synthesis.
Angewandte Chemie, 2021 SuFEx click chemistry is a powerful method designed for the selective, rapid and modular synthesis of functional molecules. Classical SuFEx reactions form stable S-O linkages upon exchange of S-F bonds with aryl silyl-ether substrates, and while near ...
C. Smedley +2 more
semanticscholar +1 more source
Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry [PDF]
, 2011 Aim of this study was the site-specific conjugation of an epidermal growth factor (EGF)-polyethylene glycol (PEG) chain by click chemistry onto a poly(amido amine) (PAMAM) dendron, as a key step toward defined multifunctional carriers for targeted gene ...
Balogh L. +59 more
core +1 more source
Click chemistry strategies for the accelerated synthesis of functional macromolecules
Journal of Polymer Science, 2021 Materials Research Laboratory, University of California, Santa Barbara, California School of Materials Science and Engineering, Beijing Institute of Technology, Beijing, China Department of Organic Materials and Fiber Engineering, Soongsil University ...
Zhishuai Geng +3 more
semanticscholar +1 more source