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Salt Metathesis: An Ultimate Click Reaction [PDF]

open access: yesPrecision Chemistry
In this Comment, we suggest salt metathesis (or ion exchange) as an ultimate click reaction, extending click chemistry principles beyond covalent bonds to ionic interactions. These universal and robust reactions, which nature utilizes in marine organisms' biomineralization processes, proceed spontaneously under mild conditions with minimal waste ...
Christopher M. Butch   +2 more
doaj   +4 more sources

Overview of 1,5-Selective Click Reaction of Azides with Alkynes or Their Synthetic Equivalents [PDF]

open access: yesMolecules, 2023
Nowadays, the click reaction of azides with alkynes has evolved rapidly and become one of the most efficient methods to synthesize 1,2,3-triazoles, which are an important class of N-containing heterocycles.
Yaqi Zhao   +3 more
doaj   +2 more sources

Development of Mixed metal Metal-organic polyhedra networks, colloids, and MOFs and their Pharmacokinetic applications [PDF]

open access: yesScientific Reports, 2017
Summary The coordination networking of discrete metal-organic polyhedra (MOPs) involving different ligands as well as metals is a challenging task due to the features of limited solubility and chemical stability of these polyhedra.
Nazir Ahmad   +6 more
doaj   +3 more sources

Post-Functionalization of Organometallic Complexes via Click-Reaction [PDF]

open access: yesMolecules, 2022
CuAAC (Cu catalyzed azide-alkyne cycloaddition) click-reaction is a simple and powerful method for the post-synthetic modification of organometallic complexes of transition metals. This approach allows the selective introduction of additional donor sites
Stanislav Petrovskii   +4 more
doaj   +2 more sources

Facile fabrication of polymer network using click chemistry and their computational study [PDF]

open access: yesRoyal Society Open Science, 2021
Click reaction is a very fast, high yield with no by-product, biocompatible, tolerant to surrounded medium, and very specific cycloaddition reaction between azides and alkynes to form triazole.
Md. Kausar Ahmed   +2 more
doaj   +1 more source

Click chemistry and drug delivery: A bird's-eye view

open access: yesActa Pharmaceutica Sinica B, 2023
Click chemistry has been proven to be very useful in drug delivery. Due to the availability of a large number of click reactions with a various characteristics, selection of appropriate chemistry for a given application is often not a trivial task.
Shameer M. Kondengadan   +5 more
doaj   +1 more source

Catalytic activity and mechanistic investigation of 1D 2-Picolinic acid based Cu(II) coordination polymer in the selective construction of 1,4-disubstituted triazoles

open access: yesScientific Reports, 2022
The catalytic activity of 1D 2-Picolinic acid based Cu (II) coordination polymer (CP1) in click reaction was evaluated to generate 1,4-disubstituted 1,2,3-triazoles selectively.
Merangmenla Aier   +2 more
doaj   +1 more source

Silver-catalysed azide–alkyne cycloaddition (AgAAC): assessing the mechanism by density functional theory calculations [PDF]

open access: yesRoyal Society Open Science, 2016
‘Click reactions’ are the copper catalysed dipolar cycloaddition reaction of azides and alkynes to incorporate nitrogens into a cyclic hydrocarbon scaffold forming a triazole ring.
Biswadip Banerji   +6 more
doaj   +1 more source

CBT‐Cys click reaction for optical bioimaging in vivo

open access: yesView, 2023
Derived from the D‐luciferin regeneration pathway in firefly body, the click condensation reaction between 2‐cyanobenzothiazole (CBT) and D‐cysteine (Cys) (CBT‐Cys click reaction) possesses unique advantages, including superior biocompatibility, high ...
Xinyi Hu   +5 more
doaj   +1 more source

A method for parallel microscale protein labeling and precise control over the average degree of labeling (aDoL)

open access: yesScientific Reports, 2023
A widely used approach for protein conjugation is through the lysine residues reacting with NHS- or other active esters. However, it is a challenge to precisely control the degree of labeling (DoL) due to the instability of active ester and variability ...
Qiaoqiao Ruan, Cheng Zhao
doaj   +1 more source

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