Salt Metathesis: An Ultimate Click Reaction [PDF]
Precision ChemistryIn this Comment, we suggest salt metathesis (or ion exchange) as an ultimate click reaction, extending click chemistry principles beyond covalent bonds to ionic interactions. These universal and robust reactions, which nature utilizes in marine organisms' biomineralization processes, proceed spontaneously under mild conditions with minimal waste ...
Christopher M. Butch +2 more
doaj +4 more sources
Photo Click Reaction of Acylsilanes with Indoles. [PDF]
Angew Chem Int Ed Engl, 2021 AbstractLight‐mediated coupling of acylsilanes with indoles is reported. This photo click reaction occurs under mild conditions (415 nm) mostly in quantitative yield and provides stable silylated N,O‐acetals via light mediated siloxycarbene generation with subsequent indole‐N‐H insertion.
Stuckhardt C, Wissing M, Studer A.
europepmc +6 more sources
Overview of 1,5-Selective Click Reaction of Azides with Alkynes or Their Synthetic Equivalents [PDF]
Molecules, 2023 Nowadays, the click reaction of azides with alkynes has evolved rapidly and become one of the most efficient methods to synthesize 1,2,3-triazoles, which are an important class of N-containing heterocycles.
Yaqi Zhao +3 more
doaj +2 more sources
Development of Mixed metal Metal-organic polyhedra networks, colloids, and MOFs and their Pharmacokinetic applications [PDF]
Scientific Reports, 2017 Summary The coordination networking of discrete metal-organic polyhedra (MOPs) involving different ligands as well as metals is a challenging task due to the features of limited solubility and chemical stability of these polyhedra.
Nazir Ahmad +6 more
doaj +3 more sources
Post-Functionalization of Organometallic Complexes via Click-Reaction [PDF]
Molecules, 2022 CuAAC (Cu catalyzed azide-alkyne cycloaddition) click-reaction is a simple and powerful method for the post-synthetic modification of organometallic complexes of transition metals. This approach allows the selective introduction of additional donor sites
Stanislav Petrovskii +4 more
doaj +2 more sources
Superstructures of fluorescent cyclodextrin via click-reaction [PDF]
Beilstein Journal of Organic Chemistry, 2013 Mono-(6-azido-6-deoxy)-β-cyclodextrin (CD) was covalently attached to an alkyne-modified 5-methyl-2-(pyridin-2-yl)thiazol-4-ol yielding a fluorophore containing CD in a click-type reaction.
Arkadius Maciollek +2 more
doaj +3 more sources
One pot ‘click’ reactions: tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition [PDF]
, 2010 Halohydrin dehalogenase (HheC) can perform enantioselective azidolysis of aromatic epoxides to 1,2-azido alcohols which are subsequently ligated to alkynes producing chiral hydroxy triazoles in a one-pot procedure with excellent enantiomeric excess.
Campbell-Verduyn, Lachlan S., +6 more
core +5 more sources
Facile fabrication of polymer network using click chemistry and their computational study [PDF]
Royal Society Open Science, 2021 Click reaction is a very fast, high yield with no by-product, biocompatible, tolerant to surrounded medium, and very specific cycloaddition reaction between azides and alkynes to form triazole.
Md. Kausar Ahmed +2 more
doaj +1 more source
Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction. [PDF]
Angew Chem Int Ed Engl, 2022 Abdelkader EH +7 more
europepmc +3 more sources
Click chemistry and drug delivery: A bird's-eye view
Acta Pharmaceutica Sinica B, 2023 Click chemistry has been proven to be very useful in drug delivery. Due to the availability of a large number of click reactions with a various characteristics, selection of appropriate chemistry for a given application is often not a trivial task.
Shameer M. Kondengadan +5 more
doaj +1 more source