Results 51 to 60 of about 595,530 (229)

Core-Clickable PEG-Branch-Azide Bivalent-Bottle-Brush Polymers by ROMP: Grafting-Through and Clicking-To [PDF]

, 2011
The combination of highly efficient polymerizations with modular "click" coupling reactions has enabled the synthesis of a wide variety of novel nanoscopic tructures.
Burts, Alan O., Finn, M. G., Grubbs, Robert H., Johnson, Jeremiah A., Koberstein, Jeffrey T., Lim, Yeon-Hee, Lu, Ying Y., Tirrell, David A., Turro, Nicholas J.   +8 more
core   +2 more sources

Modified Nucleosides, Nucleotides and Nucleic Acids via Click Azide-Alkyne Cycloaddition for Pharmacological Applications

Molecules, 2021
The click azide = alkyne 1,3-dipolar cycloaddition (click chemistry) has become the approach of choice for bioconjugations in medicinal chemistry, providing facile reaction conditions amenable to both small and biological molecules.
Daniela Perrone, Elena Marchesi, Lorenzo Preti, Maria Luisa Navacchia   +3 more
doaj   +1 more source

Acoustic behavior of melon-headed whales varies on a diel cycle. [PDF]

, 2015
Many terrestrial and marine species have a diel activity pattern, and their acoustic signaling follows their current behavioral state. Whistles and echolocation clicks on long-term recordings produced by melon-headed whales (Peponocephala electra) at ...
Baumann-Pickering, Simone, Hildebrand, John A, Roch, Marie A, Schnitzler, Hans-Ulrich, Wiggins, Sean M   +4 more
core   +2 more sources

From Micro to Marvel: Unleashing the Full Potential of Click Chemistry with Micromachine Integration

Micromachines
Micromachines, small-scale engineered devices prepared to carry out exact tasks at the micro level, have garnered great interest across different fields such as drug delivery, chemical synthesis, and biomedical applications.
Zihan Chen, Zimo Ren, Carmine Coluccini, Paolo Coghi   +3 more
doaj   +1 more source

NHC-catalyzed enantioselective access to β-cyano carboxylic esters via in situ substrate alternation and release

Nature Communications, 2023
A carbene-catalyzed asymmetric access to chiral β-cyano carboxylic esters is disclosed. The reaction proceeds between β,β-disubstituted enals and aromatic thiols involving enantioselective protonation of enal β-carbon.
Qingyun Wang, Shuquan Wu, Juan Zou, Xuyang Liang, Chengli Mou, Pengcheng Zheng, Yonggui Robin Chi   +6 more
doaj   +1 more source

Extended π-conjugated pyrene derivatives: structural, photophysical and electrochemical properties [PDF]

, 2016
This article presents a set of extended π-conjugated pyrene derivatives, namely 1,3-di(arylethynyl)-7-tert-butylpyrenes, which were synthesized by a Pd-catalyzed Sonogashira coupling reaction of 1,3-dibromo-7-tert-butylpyrenes with the corresponding ...
Bordeau, Chen, Cheng, Cheng, Chercka, Crawford, Crosby, Diring, Droumaguet, Duong, Feng, Feng, Feng, Figueira-Duarte, Han, Hu, Hu, Hu, Ito, Jeon, Karmakar, Karthik, Kim, Kim, Lee, Lee, Li, Mardanya, Mardanya, Murphy, Palatinus, Pietrangelo, Sakuda, Salunke, Sato, Sheldrick, Sung, Tang, Usta, Wang, Wang, Wu, Zhao   +42 more
core   +2 more sources

Comparative Analysis of Nanoparticle-Antibody Conjugations: Carbodiimide Versus Click Chemistry

Molecular Imaging, 2009
The ability to modify the physical, chemical, and biologic properties of nanoparticles has led to their use as multifunctional platforms for drug delivery and diagnostic imaging applications.
Daniel L.J. Thorek, ew R. Elias, Andrew Tsourkas   +2 more
doaj   +1 more source

A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações

Química Nova, 2011
The Copper-catalyzed azide-alkyne cycloaddition (CuAAC), often referred to as "click" reaction, has become a very popular reaction in the last years. It affords exclusively 1,4-disubstituted 1,2,3-triazoles and has been widely used to connect readily ...
Luiza Baptista de Oliveira Freitas, Fernando Armini Ruela, Guilherme Rocha Pereira, Rosemeire Brondi Alves, Rossimiriam Pereira de Freitas, Leandro José dos Santos   +5 more
doaj   +1 more source

Templated synthesis of cyclic poly(ionic liquid)s

, 2019
Charged cyclic polymers, e.g. cyclic DNAs and polypeptides, play enabling roles in organisms, but their synthesis was challenging due to the well known polyelectrolyte effect.
Tang, Qingquan, Yuan, Jiayin, Zhang, Weiyi, Zhao, Qiang   +3 more
core   +1 more source

Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase. [PDF]

, 2019
Nucleic Acid Therapeutics (NATs), including siRNAs and AntiSense Oligonucleotides (ASOs), have great potential to drug the undruggable genome. Targeting siRNAs and ASOs to specific cell types of interest has driven dramatic improvement in efficacy and ...
Cui, Xianshu, Dowdy, Steven F, Huggins, Ian J, Jadhav, Satish, Medina, Carlos A, Springer, Aaron D, van den Berg, Arjen   +6 more
core   +1 more source