Results 21 to 30 of about 42,190 (304)

Gating of neural error signals during motor learning

eLife, 2014
Cerebellar climbing fiber activity encodes performance errors during many motor learning tasks, but the role of these error signals in learning has been controversial.
Rhea R Kimpo, Jacob M Rinaldi, Christina K Kim, Hannah L Payne, Jennifer L Raymond   +4 more
doaj   +1 more source

Microcircuit Rules Governing Impact of Single Interneurons on Purkinje Cell Output In Vivo

Cell Reports, 2020
Summary: The functional impact of single interneurons on neuronal output in vivo and how interneurons are recruited by physiological activity patterns remain poorly understood.
Charlotte Arlt, Michael Häusser
doaj   +1 more source

The cerebellum could solve the motor error problem through error increase prediction [PDF]

, 2015
We present a cerebellar architecture with two main characteristics. The first one is that complex spikes respond to increases in sensory errors. The second one is that cerebellar modules associate particular contexts where errors have increased in the ...
O'Reilly, Randall C., Verduzco-Flores, Sergio   +1 more
core   +2 more sources

Climbing fiber coupling between adjacent Purkinje cell dendrites in vivo

Frontiers in Cellular Neuroscience, 2009
Climbing fiber discharges within the rat cerebellar cortex have been shown to display synchrony, especially for climbing fibers terminating in the same parasagittal bands.
Fredrik Bengtsson, Henrik Jörntell, Henrik Jörntell   +2 more
doaj   +1 more source

Non-synaptic signaling from cerebellar climbing fibers modulates Golgi cell activity

eLife, 2017
Golgi cells are the principal inhibitory neurons at the input stage of the cerebellum, providing feedforward and feedback inhibition through mossy fiber and parallel fiber synapses.
Angela K Nietz, Jada H Vaden, Luke T Coddington, Linda Overstreet-Wadiche, Jacques I Wadiche   +4 more
doaj   +1 more source

Specific relationship between excitatory inputs and climbing fiber receptive fields in deep cerebellar nuclear neurons. [PDF]

PLoS ONE, 2014
Many mossy fiber pathways to the neurons of the deep cerebellar nucleus (DCN) originate from the spinal motor circuitry. For cutaneously activated spinal neurons, the receptive field is a tag indicating the specific motor function the spinal neuron has ...
Fredrik Bengtsson, Henrik Jörntell
doaj   +1 more source

mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors [PDF]

, 2018
In cerebellar Purkinje cells (PCs) type-1 metabotropic glutamate (mGlu1) receptors play a key role in motor learning and drive the refinement of synaptic innervation during postnatal development.
Atsu Aiba, Cristina Zappulla, Ferdinando Nicoletti, Francesca Liberatore, Giada Mascio, Giorgio Carmignoto, Giuseppe Battaglia, Harumi Nakao, Marta Motolese, Masahiko Watanabe, Micaela Zonta, Michele Madonna, Milena Cannella, Pamela Scarselli, Roberto Gradini, Serena Notartomaso, Valeria Bruno   +16 more
core   +2 more sources

Climbing Fibers Control Purkinje Cell Representations of Behavior [PDF]

The Journal of Neuroscience, 2017
A crucial issue in understanding cerebellar function is the interaction between simple spike (SS) and complex spike (CS) discharge, the two fundamentally different activity modalities of Purkinje cells. Although several hypotheses have provided insights into the interaction, none fully explains or is completely consistent with the spectrum of ...
Martha L, Streng, Laurentiu S, Popa, Timothy J, Ebner   +2 more
openaire   +2 more sources

Attentive Learning of Sequential Handwriting Movements: A Neural Network Model [PDF]

, 2000
Defense Advanced research Projects Agency and the Office of Naval Research (N00014-95-1-0409, N00014-92-J-1309); National Science Foundation (IRI-97-20333); National Institutes of Health (I-R29-DC02952-01)
A. Berardelli, A. Dagher, A. Thomassen, A. Thomassen, A.B. Schwartz, A.P. Georgopoulos, A.P. Georgopoulos, A.P. Georgopoulos, A.P. Georgopoulos, A.W. Gemmert van, B.D. Kretschmer, C. Fowler, C. Ghez, C.E. Wright, D. Bullock, D. Bullock, D. Bullock, D. Bullock, D. Bullock, D. Bullock, D. Ostry, D. Zipser, D.M. Bannerman, D.V. Buonomano, E. Bizzi, E.M. Arroyo-Anllo, F. Chapeau-Blondeau, F. Lacquaniti, F. Mussa-Ivaldi, F. Richer, F.B. Horak, F.B. Horak, F.N. Freeman, G.P. Galen van, G.P. Galen van, G.T. Bartha, I. Hertrich, J. Alston, J. Doyon, J. Fiala, J. Schillings, J. Soechting, J. Wann, J.A. Freeman, J.B. Hopfinger, J.D. Coltz, J.D. Coltz, J.F. Kalaska, J.I. Simpson, J.J. Waite, J.M. Hollerbach, J.P. Wann, J.W. Moore, K. Greer, M. Hallett, M. Iacoboni, M. Ito, M. Ito, M. Ito, M. Jueptner, M. Jueptner, M. Jueptner, M.G. Pleskacheva, M.T. Turvey, N. Bernstein, N. Sadato, O. Oscarsson, P. Morasso, P. Morasso, P. Morasso, P. Vindras, P.C. Burns, Q.G. Fu, R. Andersen, R. Andersen, R. Caminiti, R. Gellman, R. Kawashima, R. Plamondon, R.S. Turner, R.S. Turner, S. Chieffi, S. Edelman, S. Grossberg, S. Grossberg, S. Grossberg, S. Jaffe, S. Ohman, S.P. Perrett, T.J. Ebner, T.L. Zhou, T.S. Buchanan, W. Abend, X. Lu   +93 more
core   +2 more sources

Parallel Fiber and Climbing Fiber Responses in Rat Cerebellar Cortical Neurons in vivo

Frontiers in Systems Neuroscience, 2013
Over the last few years we have seen a rapidly increased interest in the functions of the inhibitory interneurons of the cerebellar cortex. However, we still have very limited knowledge about their physiological properties in vivo.
Dan-Anders eJirenhed, Fredrik eBengtsson, Henrik eJörntell   +2 more
doaj   +1 more source