Results 31 to 40 of about 42,190 (304)
Beyond all-or-nothing climbing fibers: graded representation of teaching signals in Purkinje cells
Arguments about the function of the climbing fiber input to the cerebellar cortex have fueled a rabid debate that started over forty years ago, and continues to polarize the field to this day. The origin of the controversy can be traced back to 1969, the
Farzaneh eNajafi, Javier F Medina
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Climbing fibers predict movement kinematics and performance errors [PDF]
Requisite for understanding cerebellar function is a complete characterization of the signals provided by complex spike (CS) discharge of Purkinje cells, the output neurons of the cerebellar cortex. Numerous studies have provided insights into CS function, with the most predominant view being that they are evoked by error events.
Martha L, Streng +2 more
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Morphometric evidences for regional variation in potential of neural plasticity [PDF]
The neural plasticity showing the ability of nervous system to change its structure and function is a well-documented fact. However regional variation within a CNS structure to undergo plastic changes has been shown by limited studies.
Behnampour, N. +3 more
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Structural plasticity of climbing fibers and the growth-associated protein GAP-43
Structural plasticity occurs physiologically or after brain damage to adapt or re-establish proper synaptic connections. This capacity depends on several intrinsic and extrinsic determinants that differ between neuron types.
Giorgio eGrasselli, Piergiorgio eStrata
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Climbing fiber synapse elimination in cerebellar Purkinje cells [PDF]
AbstractInnervation of Purkinje cells (PCs) by multiple climbing fibers (CFs) is refined into mono‐innervation during the first three postnatal weeks of rodents’ lives. In this review article, we will integrate the current knowledge on developmental process and mechanisms of CF synapse elimination.
Watanabe, Masahiko, Kano, Masanobu
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Nitric oxide and synaptic function [PDF]
The free radical gas nitric oxide (NO) is a recently identified neuronal messenger that carries out diverse signaling tasks in both the central and peripheral nervous systems.
Madison, Daniel V., Schuman, Erin M.
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Multivesicular Release at Climbing Fiber-Purkinje Cell Synapses [PDF]
Synapses driven by action potentials are thought to release transmitter in an all-or-none fashion; either one synaptic vesicle undergoes exocytosis, or there is no release. We have estimated the glutamate concentration transient at climbing fiber synapses on Purkinje cells by measuring the inhibition of excitatory postsynaptic currents (EPSCs) produced
Wadiche, Jacques I., Jahr, Craig E.
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Memory consolidation in the cerebellar cortex [PDF]
Several forms of learning, including classical conditioning of the eyeblink, depend upon the cerebellum. In examining mechanisms of eyeblink conditioning in rabbits, reversible inactivations of the control circuitry have begun to dissociate aspects of ...
A Gruart +54 more
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High-rise building machines (HBMs) are commonly used for the construction of super-high skyscrapers. Monitoring and early warning are critical to ensure the safety of giant HBMs during dynamic climbing.
Xi Pan +3 more
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Ketamine and Xylazine Depress Sensory-Evoked Parallel Fiber and Climbing Fiber Responses [PDF]
The last few years have seen an increase in the variety of in vivo experiments used for studying cerebellar physiological mechanisms. A combination of ketamine and xylazine has become a particularly popular form of anesthesia. However, because nonanesthetized control conditions are lacking in these experiments, so far there has been no evaluation of ...
Bengtsson, Fredrik, Jörntell, Henrik
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