Results 31 to 40 of about 42,190 (304)

Beyond all-or-nothing climbing fibers: graded representation of teaching signals in Purkinje cells

open access: yesFrontiers in Neural Circuits, 2013
Arguments about the function of the climbing fiber input to the cerebellar cortex have fueled a rabid debate that started over forty years ago, and continues to polarize the field to this day. The origin of the controversy can be traced back to 1969, the
Farzaneh eNajafi, Javier F Medina
doaj   +1 more source

Climbing fibers predict movement kinematics and performance errors [PDF]

open access: yesJournal of Neurophysiology, 2017
Requisite for understanding cerebellar function is a complete characterization of the signals provided by complex spike (CS) discharge of Purkinje cells, the output neurons of the cerebellar cortex. Numerous studies have provided insights into CS function, with the most predominant view being that they are evoked by error events.
Martha L, Streng   +2 more
openaire   +2 more sources

Morphometric evidences for regional variation in potential of neural plasticity [PDF]

open access: yes, 2006
The neural plasticity showing the ability of nervous system to change its structure and function is a well-documented fact. However regional variation within a CNS structure to undergo plastic changes has been shown by limited studies.
Behnampour, N.   +3 more
core   +1 more source

Structural plasticity of climbing fibers and the growth-associated protein GAP-43

open access: yesFrontiers in Neural Circuits, 2013
Structural plasticity occurs physiologically or after brain damage to adapt or re-establish proper synaptic connections. This capacity depends on several intrinsic and extrinsic determinants that differ between neuron types.
Giorgio eGrasselli, Piergiorgio eStrata
doaj   +1 more source

Climbing fiber synapse elimination in cerebellar Purkinje cells [PDF]

open access: yesEuropean Journal of Neuroscience, 2011
AbstractInnervation of Purkinje cells (PCs) by multiple climbing fibers (CFs) is refined into mono‐innervation during the first three postnatal weeks of rodents’ lives. In this review article, we will integrate the current knowledge on developmental process and mechanisms of CF synapse elimination.
Watanabe, Masahiko, Kano, Masanobu
openaire   +3 more sources

Nitric oxide and synaptic function [PDF]

open access: yes, 1994
The free radical gas nitric oxide (NO) is a recently identified neuronal messenger that carries out diverse signaling tasks in both the central and peripheral nervous systems.
Madison, Daniel V., Schuman, Erin M.
core   +1 more source

Multivesicular Release at Climbing Fiber-Purkinje Cell Synapses [PDF]

open access: yesNeuron, 2001
Synapses driven by action potentials are thought to release transmitter in an all-or-none fashion; either one synaptic vesicle undergoes exocytosis, or there is no release. We have estimated the glutamate concentration transient at climbing fiber synapses on Purkinje cells by measuring the inhibition of excitatory postsynaptic currents (EPSCs) produced
Wadiche, Jacques I., Jahr, Craig E.
openaire   +2 more sources

Memory consolidation in the cerebellar cortex [PDF]

open access: yes, 2010
Several forms of learning, including classical conditioning of the eyeblink, depend upon the cerebellum. In examining mechanisms of eyeblink conditioning in rabbits, reversible inactivations of the control circuitry have begun to dissociate aspects of ...
A Gruart   +54 more
core   +4 more sources

Research on Dynamic Monitoring and Early Warning of the High-Rise Building Machine during the Climbing Stage

open access: yesAdvances in Civil Engineering, 2023
High-rise building machines (HBMs) are commonly used for the construction of super-high skyscrapers. Monitoring and early warning are critical to ensure the safety of giant HBMs during dynamic climbing.
Xi Pan   +3 more
doaj   +1 more source

Ketamine and Xylazine Depress Sensory-Evoked Parallel Fiber and Climbing Fiber Responses [PDF]

open access: yesJournal of Neurophysiology, 2007
The last few years have seen an increase in the variety of in vivo experiments used for studying cerebellar physiological mechanisms. A combination of ketamine and xylazine has become a particularly popular form of anesthesia. However, because nonanesthetized control conditions are lacking in these experiments, so far there has been no evaluation of ...
Bengtsson, Fredrik, Jörntell, Henrik
openaire   +3 more sources

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