Results 171 to 180 of about 437,074 (308)

Plasmid-encoded Pgp3 protein enhances the infectivity of <i>Chlamydia trachomatis</i> serovar L2 in mice. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Sun X, Zhang Q, Tian Q, Xue M, Zhong G, Wang L.   +5 more
europepmc   +1 more source

Human cloning: three mistakes and an alternative

, 2002
The current debate on the ethics of cloning humans is both uninspired and uninspiring. In large measure this is because of mistakes that permeate the discourse, including the mistake of thinking that cloning technology is strictly a reproductive ...
Baylis, Francoise
core  

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

The persistence of potential: The life of Sir John B. Gurdon. [PDF]

Proc Natl Acad Sci U S A
Melton DA, De Robertis EM.
europepmc   +1 more source

Who is the parent in cloning?

, 1999
Symposium On Human Cloning: Legal, Social, and Moral Perspectives for the Twenty-First ...
Elster, Nanette
core  

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Targeting mitochondrial ribosomal proteins: a functional and translational framework for neurodegenerative disease research. [PDF]

Front Neurol
Del Giudice L, Guida M, Aletta MR, Pontieri P.   +3 more
europepmc   +1 more source

Therapeutic cloning: from consequences to contradiction

, 2002
The British Parliament legalized therapeutic cloning in December 2000 despite opposition from the European Union. The watershed event in Parliament's move was the active and unprecedented government support for the generation and destruction of human ...
Coors, Marilyn E.
core  

Continuous Evolution System Based on Toxin–Antitoxin System Combined with Base Deaminase Accelerates the In Vivo Modification of Target Proteins

Advanced Science, EarlyView.
The promoted Escherichia coli‐assisted continuous evolution (PEACE) system operates through a stringent three step genetic circuit: target gene mutation via a deaminase–T7 RNA polymerase (T7 RNAP) fusion, coupling variant function to antitoxin expression, and growth based selection of surviving cells.
Xinyu Zhang, Zhanzhi Liu, Ying Xu, Mingjing Sun, Guangzhen Zhou, Deming Rao, Xiaoqian Chen, Sheng Wang, Zhigang Li, Yan Huang, Jing Wu   +10 more
wiley   +1 more source

One-step generation of semi-cloned zebrafish carrying a defined genetic modification. [PDF]

Cell Res
Ai Y, Li S, Liu S, Xu J, Zhang Y, Zhou S, Zhou Z, Li J, Li Y.   +8 more
europepmc   +1 more source