Results 271 to 280 of about 169,769 (295)

Cloning, expression, and genomic organization of mouse mp29 gene

Biochemical and Biophysical Research Communications, 2002
Human p29 has been demonstrated in the yeast two-hybrid method and in vitro GST pull-down assay to associate with GCIP, a cyclin D interacting protein. In this study, we describe the cloning and genomic structure of the mouse homologue, mp29. The overall mouse mp29 amino acid sequence is highly identical (91%) to human p29.
Chang Jen Huang, Yuh Cheng Yang, Chi Chen Fan, Hung I Yeh, Chiung Ya Chen, Mau-Sun Chang   +5 more
openaire   +3 more sources

Whole-organism clone tracing using single-cell sequencing

Nature, 2018
Embryonic development is a crucial period in the life of a multicellular organism, during which limited sets of embryonic progenitors produce all cells in the adult body. Determining which fate these progenitors acquire in adult tissues requires the simultaneous measurement of clonal history and cell identity at single-cell resolution, which has been a
Alemany, Anna, Florescu, Maria, Baron, Chloé S., Peterson-Maduro, Josi, van Oudenaarden, Alexander   +4 more
openaire   +4 more sources

Cloning and Functional Expression of a Human Liver Organic Cation Transporter

Molecular Pharmacology, 1997
Polyspecific organic cation transporters in the liver mediate the elimination of a wide array of endogenous amines and xenobiotics. In contrast to our understanding of the mechanisms of organic cation transport in rat liver, little is known about the mechanisms of organic cation transport in the human liver.
Andrew T. Gray, Kathleen M. Giacomini, Mark J. Dresser, Spencer C. Yost, Shigeyuki Terashita, Lei Zhang   +5 more
openaire   +3 more sources

Genomic organization and cloning of the human homologue of murine Sipa-1

Gene, 1998
Murine Sipa-1 (signal-induced proliferation associated protein) is a mitogen induced GTPase activating protein (GAP). While mapping candidate genes for multiple endocrine neoplasia type 1 (MEN1) at 11q13, we cloned the human homologue of Sipa-1. Herein, we report the complete cDNA sequence, expression, and genomic organization of SIPA-1.
Mark P. Sawicki, Eric Wang, Elizabeth Arnold, Nitin Udar, Kent W. Small, David Burbee, Sam A. Ebrahimi   +6 more
openaire   +3 more sources

Genetic organization and cloning of kirsten murine sarcoma virus DNA

Biochemical and Biophysical Research Communications, 1982
Summary The Kirsten murine sarcoma virus genome is a recombinant molecule derived from the Kirsten murine leukemia virus genome and sequences transduced from a normal rat cell. We show here that leukemia virus derived sequences comprise the 5′ terminal 0.5 kilobasepairs (kbp) and the 3′ terminal 1.2 kbp of the linear 6.5 kbp sarcoma virus DNA.
Roger J. Avery, John Norton
openaire   +3 more sources

Cloning, Genomic Organization, and Tissue Distribution of Human Ssf-1

Biochemical and Biophysical Research Communications, 2000
During the screening of a human placenta cDNA library, realized in order to isolate the P2Y(11) coding sequence, an unrelated cDNA was cloned. We identified a 1422 bp open reading frame encoding a human protein displaying 40% amino acid identity with the Saccharomyces cerevisiae Ssf-1, a protein involved in the second step of mRNA splicing.
Suarez Gonzalez, Nathalie, Boeynaems, Jean-Marie, Communi, Didier   +2 more
openaire   +3 more sources

Molecular and Functional Characteristics of Cloned Human Organic Cation Transporters [PDF]

, 2005
Within the last 5 years the organic cation transport field has moved from tissue and cellular levels to a molecular level of investigation. As we gain a better understanding of the genes and proteins responsible for the multiple mechanisms of organic cation transport, we can begin to apply this knowledge to pharmaceutical and drug discovery research ...
Kathleen M. Giacomini, Mark J. Dresser, Lei Zhang   +2 more
openaire   +2 more sources

cDNA cloning, structural organization, and expression of the sheep NRAMP1 gene

Mammalian Genome, 1998
Mouse resistance to several intracellular pathogens including Mycobacteria, Leishmania, and Salmonella is under the control of the Chromosome (Chr) 1 Natural Resistance Associated Macrophage Protein I gene (Nramp1). This gene could have an economic and health importance for domestic animals and humans as well.
F. Nau, Philippe Gros, Frédéric Lantier, Isabelle Lantier, Frédérique Pitel, Sylvie Patri, Jean Michel Elsen, Vincent Bussmann   +7 more
openaire   +3 more sources

Gene Cloning in Organisms Other Than E. coli

1982
Cloning Vectors Derived from Plasmids and Phage of Bacillus.- Use of Plasmids from Staphylococcus aureus for Cloning of DNA in Bacillus subtilis.- Vectors for Gene Cloning in Pseudomonas and Their Applications.- Host: Vector Systems for Gene Cloning in Pseudomonas.- Gene Cloning in Streptomyces.- Gene Cloning in Neurospora crassa.- Vectors for Cloning ...
P. H. Hofschneider, W. Goebel
openaire   +2 more sources

Cloning of Aged Animals A Medical Model for Tissue and Organ Regeneration

Trends in Cardiovascular Medicine, 2001
Cloning by nuclear transfer has great potential application in pharmaceutical protein production, xeno-transplantation, and perhaps most excitingly, therapeutic cloning. In therapeutic cloning a patient's own skin cells can be used to generate cloned embryos from which embryonic stem cells are isolated.
X.C Tian, Xiangzhong Yang, Chikara Kubota   +2 more
openaire   +2 more sources