Results 101 to 110 of about 18,135 (204)

Role of Hsp100/Clp Protease Complexes in Controlling the Regulation of Motility in Bacillus subtilis [PDF]

, 2016
The Hsp100/Clp protease complexes of Bacillus subtilis ClpXP and ClpCP are involved in the control of many interconnected developmental and stress response regulatory networks, including competence, redox stress response, and motility.
Hoßmann, Jörn, Molière, Noël, Schäfer, Heinrich, Turgay, Kürşad   +3 more
core   +3 more sources

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection

Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon, Victoria R. Wong, Samuelson E. Osifo, Timothy Edwards, Himanshu Rao, Jewelia Rempuszewski, Andrew J. Frear, Shaan Sadhwani, Neel B. Shah, Kenneth L. Urish   +9 more
wiley   +1 more source

Subunit asymmetry and roles of conformational switching in the hexameric AAA+ ring of ClpX [PDF]

, 2015
The hexameric AAA+ ring of Escherichia coli ClpX, an ATP-dependent machine for protein unfolding and translocation, functions with the ClpP peptidase to degrade target substrates.
A Martin, Benjamin M Stinson, BM Stinson, DM Smith, G Thibault, GC Lander, GL Hersch, I Chen, JA Kenniston, JA Kenniston, JC Cordova, JG Nørby, JJ Lavinder, JW Taraska, Karl R Schmitz, M Sen, M-E Aubin-Tam, ME Matyskiela, MW Popp, R Beckwith, RA Maillard, RE Burton, Robert T Sauer, RT Sauer, SA Joshi, SE Glynn, TA Baker, Tania A Baker, TP Geladopoulos, UA Wojtyra, Vladimir Baytshtok, YI Kim, YI Kim   +32 more
core   +2 more sources

Azlocillin can be the potential drug candidate against drug-tolerant Borrelia burgdorferi sensu stricto JLB31. [PDF]

, 2020
Lyme disease is one of most common vector-borne diseases, reporting more than 300,000 cases annually in the United States. Treating Lyme disease during its initial stages with traditional tetracycline antibiotics is effective. However, 10-20% of patients
Ahmed, Mohamed Sohail, Ambati, Aditya, Inayathullah, Mohammed, Mallajosyula, Venkata Vamsee Aditya, Pothineni, Venkata Raveendra, Potula, Hari-Hara SK, Rajadas, Jayakumar, Sridharan, Brindha   +7 more
core  

Protein degradation in bacteria: focus on the ClpP protease

Nippon Saikingaku Zasshi
Proteins in the cells are born (synthesized), work, and die (decomposed). In the life of a protein, its birth is obviously important, but how it dies is equally important in living organisms. Proteases secreted into the outside of cells are used to decompose the external proteins and the degradation products are taken as the nutrients.
Fumihiro, Ishikawa, Michio, Homma, Genzoh, Tanabe, Takayuki, Uchihashi   +3 more
openaire   +2 more sources

Changes to soil quality indicators following conversion to organic vegetable production (OF0401) [PDF]

, 2002
This is the final report of Defra project OF0401. The attached report document starts with an Executive Summary, from which this text is extracted. The aim of this 1 year study was to examine how key functional indicators of soil quality are affected by
Bending, Gary
core  

Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments [PDF]

, 2018
Multidrug-resistant Acinetobacter baumannii, a major hospital-acquired pathogen, is a serious health threat and poses a great challenge to healthcare providers.
Chan, Ting-Fung, Fong-Chuen Loo, Jacky, Ip, Margaret, Lau, Terrence Chi-Kong, Lin, Xiao, Qin, Hao, Tsui, Stephen Kwok-Wing, Wai-Sing Lo, Norman, Yim, Aldrin Kay-Yuen   +8 more
core   +2 more sources

Mechanism of allosteric activation in human mitochondrial ClpP protease

Proceedings of the National Academy of Sciences
AbstractHuman ClpP protease contributes to mitochondrial protein quality control by degrading misfolded proteins. ClpP is overexpressed in cancers such as acute myeloid leukemia (AML), where its inhibition leads to the accumulation of damaged respiratory chain subunits and cell death.
Monica M. Goncalves, Adwaith B. Uday, Taylor J. B. Forrester, S. Quinn W. Currie, Angelina S. Kim, Yue Feng, Yulia Jitkova, Algirdas Velyvis, Robert W. Harkness, Matthew S. Kimber, Aaron D. Schimmer, Natalie Zeytuni, Siavash Vahidi   +12 more
openaire   +2 more sources

Molecular insights into the dynamic modulation of bacterial ClpP function and oligomerization by peptidomimetic boronate compounds

Scientific Reports
Bacterial caseinolytic protease P subunit (ClpP) is important and vital for cell survival and infectivity. Recent publications describe and discuss the complex structure–function relationship of ClpP and its processive activity mediated by 14 catalytic ...
Bruno Alves França, Sven Falke, Holger Rohde, Christian Betzel   +3 more
doaj   +1 more source

Pressure‐dependent adaptation strategies implied by the dissimilatory iron reducer Orenia metallireducens Z6

mLife, Volume 5, Issue 1, Page 122-125, February 2026.
Shuyi Li, Jiahao Pei, Jiasong Fang, Rulong Liu, Yuli Wei, Xianyu Huang, Guang Yang, Min Liu, Qin Lin, Robert R. Sanford, Hongbo Shao, Yongguang Jiang, Yidan Hu, Zhou Jiang, Qi Feng, Yu He, Chenxi Zhang, Yizhou Fan, Yiran Dong, Liang Shi   +19 more
wiley   +1 more source