Results 71 to 80 of about 18,307 (208)

Soil Disturbance Increases Soil Microbial Enzymatic Activity in Arid Ecoregions [PDF]

open access: yes, 2011
Functional diversity of the soil microbial community is commonly used in the assessment of soil health as it relates to the activity of soil microflora involved in carbon cycling.
Adrian Unc   +2 more
core   +2 more sources

Complete Chloroplast Genomes of Ranunculus arvensis and Ranunculus laetus: Comparative Analysis and Phylogenetic Insights

open access: yesEcology and Evolution, Volume 16, Issue 5, May 2026.
Here, we de novo assembled the chloroplast genomes of Ranunculus arvensis and Ranunculus laetus, providing comprehensive comparative analysis with 21 congeners. The genomes exhibited conserved quadripartite structures with no major rearrangements, though lineage‐specific variations in atpH position were detected in two species.
Hui Li   +10 more
wiley   +1 more source

Comparative Chloroplast Genomics of Cousinia (Asteraceae) With Nine Newly Sequenced Endemic Species From Central Asia

open access: yesEcology and Evolution, Volume 16, Issue 5, May 2026.
In this study, nine complete chloroplast genomes of Cousinia species endemic to the Pamir–Alay mountain system were sequenced and analyzed together with previously published plastomes and nuclear ribosomal ITS data. ABSTRACT Cousinia (Asteraceae: Cardueae) represents one of the most species‐rich genera within the Irano–Turanian floristic region, yet ...
Bobur Karimov   +10 more
wiley   +1 more source

Chloroplast Phylogenomics and Barcode Discovery in Medicinal Stachys Species Reveal Evolutionary Relationships and Adaptive Signatures

open access: yesEcology and Evolution, Volume 16, Issue 5, May 2026.
This study presents the first complete chloroplast genomes of two medicinally important Stachys species, S. persica and S. germanica. Comparative phylogenomic analyses revealed highly conserved genomes with lineage‐specific variations, identified hypervariable regions as candidate DNA barcodes, and detected signatures of positive selection in the petB ...
Fatemeh Sadat Ghotbi, Aboozar Soorni
wiley   +1 more source

Highly Dynamic Interactions Maintain Kinetic Stability of the ClpXP Protease During the ATP-Fueled Mechanical Cycle [PDF]

open access: yes, 2016
The ClpXP protease assembles in a reaction in which an ATP-bound ring hexamer of ClpX binds to one or both heptameric rings of the ClpP peptidase. Contacts between ClpX IGF-loops and clefts on a ClpP ring stabilize the complex.
Amor, Alvaro Jorge   +4 more
core   +1 more source

Chemical Activators of ClpP: Turning Jekyll into Hyde

open access: yesChemistry & Biology, 2011
Casein lytic peptidase P (ClpP) is a serine peptidase that, when coupled to its cognate ATPase, facilitates the controlled degradation of both damaged and unwanted proteins in bacteria. In this issue of Chemistry & Biology, Leung et al. (2011) report a small molecule screen against ClpP, from which they identified four structurally distinct compounds ...
openaire   +2 more sources

HSPA8-mediated stability of the CLPP protein regulates mitochondrial autophagy in cisplatin-resistant ovarian cancer cells

open access: yesActa Biochimica et Biophysica Sinica
Currently, platinum agents remain the mainstay of chemotherapy for ovarian cancer (OC). However, cisplatin (DDP) resistance is a major reason for chemotherapy failure.
Kou Xinxin   +3 more
doaj   +1 more source

Cell Division Protein FtsZ Is Unfolded for N-Terminal Degradation by Antibiotic-Activated ClpP

open access: yesmBio, 2020
Antibiotic acyldepsipeptides (ADEPs) deregulate ClpP, the proteolytic core of the bacterial Clp protease, thereby inhibiting its native functions and concomitantly activating it for uncontrolled proteolysis of nonnative substrates.
Nadine Silber   +5 more
doaj   +1 more source

Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS

open access: yesPROTEOMICS, Volume 26, Issue 5, Page 27-36, May 2026.
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor   +3 more
wiley   +1 more source

CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis [PDF]

open access: yesEMBO reports, 2018
Mitochondria are fundamental for cellular metabolism as they are both a source and a target of nutrient intermediates originating from converging metabolic pathways, and their role in the regulation of systemic metabolism is increasingly recognized. Thus, maintenance of mitochondrial homeostasis is indispensable for a functional energy metabolism of ...
Christina Becker   +7 more
openaire   +2 more sources

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