Results 71 to 80 of about 18,307 (208)
Soil Disturbance Increases Soil Microbial Enzymatic Activity in Arid Ecoregions [PDF]
Functional diversity of the soil microbial community is commonly used in the assessment of soil health as it relates to the activity of soil microflora involved in carbon cycling.
Adrian Unc +2 more
core +2 more sources
Here, we de novo assembled the chloroplast genomes of Ranunculus arvensis and Ranunculus laetus, providing comprehensive comparative analysis with 21 congeners. The genomes exhibited conserved quadripartite structures with no major rearrangements, though lineage‐specific variations in atpH position were detected in two species.
Hui Li +10 more
wiley +1 more source
In this study, nine complete chloroplast genomes of Cousinia species endemic to the Pamir–Alay mountain system were sequenced and analyzed together with previously published plastomes and nuclear ribosomal ITS data. ABSTRACT Cousinia (Asteraceae: Cardueae) represents one of the most species‐rich genera within the Irano–Turanian floristic region, yet ...
Bobur Karimov +10 more
wiley +1 more source
This study presents the first complete chloroplast genomes of two medicinally important Stachys species, S. persica and S. germanica. Comparative phylogenomic analyses revealed highly conserved genomes with lineage‐specific variations, identified hypervariable regions as candidate DNA barcodes, and detected signatures of positive selection in the petB ...
Fatemeh Sadat Ghotbi, Aboozar Soorni
wiley +1 more source
Highly Dynamic Interactions Maintain Kinetic Stability of the ClpXP Protease During the ATP-Fueled Mechanical Cycle [PDF]
The ClpXP protease assembles in a reaction in which an ATP-bound ring hexamer of ClpX binds to one or both heptameric rings of the ClpP peptidase. Contacts between ClpX IGF-loops and clefts on a ClpP ring stabilize the complex.
Amor, Alvaro Jorge +4 more
core +1 more source
Chemical Activators of ClpP: Turning Jekyll into Hyde
Casein lytic peptidase P (ClpP) is a serine peptidase that, when coupled to its cognate ATPase, facilitates the controlled degradation of both damaged and unwanted proteins in bacteria. In this issue of Chemistry & Biology, Leung et al. (2011) report a small molecule screen against ClpP, from which they identified four structurally distinct compounds ...
openaire +2 more sources
Currently, platinum agents remain the mainstay of chemotherapy for ovarian cancer (OC). However, cisplatin (DDP) resistance is a major reason for chemotherapy failure.
Kou Xinxin +3 more
doaj +1 more source
Cell Division Protein FtsZ Is Unfolded for N-Terminal Degradation by Antibiotic-Activated ClpP
Antibiotic acyldepsipeptides (ADEPs) deregulate ClpP, the proteolytic core of the bacterial Clp protease, thereby inhibiting its native functions and concomitantly activating it for uncontrolled proteolysis of nonnative substrates.
Nadine Silber +5 more
doaj +1 more source
Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor +3 more
wiley +1 more source
Mitochondria are fundamental for cellular metabolism as they are both a source and a target of nutrient intermediates originating from converging metabolic pathways, and their role in the regulation of systemic metabolism is increasingly recognized. Thus, maintenance of mitochondrial homeostasis is indispensable for a functional energy metabolism of ...
Christina Becker +7 more
openaire +2 more sources

