Results 71 to 80 of about 13,032 (201)
Plastomes of Ten Blumea Species (Asteraceae): Comparative Analysis and Phylogenetic Relationships
Comparative analysis of ten Blumea plastomes revealed conserved genome architecture and identified mutation hotspots and positively selected genes. Phylogenetic reconstruction clarified the genus's position within Inuleae and supported its monophyly. This study provides valuable genomic resources for Blumea. ABSTRACT Blumea (Asteraceae) comprises about
Yuemei Zhao +7 more
wiley +1 more source
Investigating The Role Of ClpP- And ClpX-Mediated Antimicrobial Resistance In Bacillus Anthracis
The regulatory ATPase ClpX in Bacillus anthracis contributes to resistance against cell-wall active antibiotics. ClpX can function independently as a chaperone or together with ClpP to form the ClpXP protease.
Zou, Lang
core
This study leverages complete plastid and nuclear ribosomal DNA sequences from 40 species to resolve the complex phylogeny and organellar genome evolution of the diverse plant tribe Elatostemateae. The analysis uncovered significant plastome structural variations, including novel inversions and a rare mitochondrial DNA integration event, and identified
Long‐Fei Fu +5 more
wiley +1 more source
S2 Appendix. Community level physiological profiles (CLPP) analysis method
Community level physiological profiles (CLPP) analysis ...
Zeyan Wu (718691), Zeyan Wu (743446)
core +1 more source
Development of Antibiotics That Dysregulate the Neisserial ClpP Protease
Evolving antimicrobial resistance has motivated the search for novel targets and alternative therapies. Caseinolytic protease (ClpP) has emerged as an enticing new target since its function is conserved and essential for bacterial fitness, and because its inhibition or dysregulation leads to bacterial cell death.
Gursonika Binepal +14 more
openaire +3 more sources
We assembled and characterized the complete chloroplast genome of Dioscorea hypoglauca, a medicinally important yam species from southern China. The 153,219 bp genome exhibits a typical quadripartite structure, containing 129 genes (84 protein‐coding, 37 tRNA, and 8 rRNA genes), and comparative analyses with 22 other Dioscorea species revealed dynamic ...
Gang Li +5 more
wiley +1 more source
Structure of Staphylococcus aureus ClpP Bound to the Covalent Active‐Site Inhibitor Cystargolide A [PDF]
The caseinolytic protease is a highly conserved serine protease, crucial to prokaryotic and eukaryotic protein homeostasis, and a promising antibacterial and anticancer drug target.
Kaysser, Leonard +15 more
core +1 more source
Protein degradation in bacteria: focus on the ClpP protease
Proteins in the cells are born (synthesized), work, and die (decomposed). In the life of a protein, its birth is obviously important, but how it dies is equally important in living organisms. Proteases secreted into the outside of cells are used to decompose the external proteins and the degradation products are taken as the nutrients.
Fumihiro, Ishikawa +3 more
openaire +2 more sources
Currently, platinum agents remain the mainstay of chemotherapy for ovarian cancer (OC). However, cisplatin (DDP) resistance is a major reason for chemotherapy failure.
Kou Xinxin +3 more
doaj +1 more source
This study assembled the first complete chloroplast genome of the endemic medicinal plant Zingiber emeiense, revealing its genomic structure and evolutionary features as well as clarifying its phylogenetic placement. It further provides valuable genomic resources for the conservation and taxonomic research of this endemic species.
Hualan Chen +11 more
wiley +1 more source

