Results 81 to 90 of about 18,135 (204)

CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis [PDF]

open access: yesEMBO reports, 2018
Mitochondria are fundamental for cellular metabolism as they are both a source and a target of nutrient intermediates originating from converging metabolic pathways, and their role in the regulation of systemic metabolism is increasingly recognized. Thus, maintenance of mitochondrial homeostasis is indispensable for a functional energy metabolism of ...
Christina Becker   +7 more
openaire   +2 more sources

Purification of the Caseinolytic protease ClpP.

open access: yes, 2022
The caseinolytic protease P (ClpP) is an essential protein for bacteria and bacterial derived organelles. It belongs to the AAA+ family of proteases and has proteolytic activity, thereby, it plays an important role in protein digestion. This protease is involved in essential processes such as, cellular regulatory mechanisms, protein homeostasis ...
Pedrós Manzanares, Laura   +1 more
openaire   +1 more source

Development of prediction model for risks of musculoskeletal chronic lumbopelvic pain in Indian women

open access: yesScientific Reports
Chronic lumbopelvic pain (CLPP) and its associated disabilities significantly affect women's social, professional, and personal lives. However, the specific factors contributing to CLPP in women remain unclear. To address this gap, this prospective cross-
Jasmine Kaur Chawla   +4 more
doaj   +1 more source

Impact of soil management on the functional activity of microbial communities associated to cork oak rhizosphere [PDF]

open access: yes, 2007
The microbial ecology of cork oak rhizosphere was investigated using the Biolog community level physiological profile (CLPP) that provides a unique metabolic fingerprint helpful for the characterization of complex microbial communities.
Caredda, Marco   +3 more
core  

Mutation in human CLPX elevates levels of δ-aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria [PDF]

open access: yes, 2017
Loss-of-function mutations in genes for heme biosynthetic enzymes can give rise to congenital porphyrias, eight forms of which have been described. The genetic penetrance of the porphyrias is clinically variable, underscoring the role of additional ...
Baker, Tania   +14 more
core   +3 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, Volume 16, Issue 3, Page 503-519, March 2026.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Cigarette Litter Prevention at the Virginia Beach Oceanfront [PDF]

open access: yes, 2020
: A city based on tourism, military installations, agriculture, and home to the first landing of Jamestown colonists, Virginia Beach boasts 28 miles of coastline along the Chesapeake Bay and Atlantic Ocean.

core  

Mechanochemical basis of protein degradation by a double-ring AAA+ machine [PDF]

open access: yes, 2014
Molecular machines containing double or single AAA+ rings power energy-dependent protein degradation and other critical cellular processes, including disaggregation and remodeling of macromolecular complexes.
A Martin   +48 more
core   +1 more source

Mitophagy and Ubiquitination Coordinate Context‐Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao   +3 more
wiley   +1 more source

ClpP: A distinctive family of cylindrical energy‐dependent serine proteases

open access: yesFEBS Letters, 2007
Processes maintaining protein homeostasis in the cell are governed by the activities of molecular chaperones that mainly assist in the folding of polypeptide chains and by a large class of proteases that regulate protein levels through degradation. ClpP proteases define a distinctive family of cylindrical, energy‐dependent serine proteases that are ...
Yu, Angela Yeou Hsiung, Houry, Walid A.
openaire   +2 more sources

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