Results 111 to 120 of about 4,851 (193)

Recognition, targeting, and hydrolysis of the lambda O replication protein by the ClpP/ClpX protease

, 1999
It has previously been established that sequences at the C termini of polypeptide substrates are critical for efficient hydrolysis by the ClpP/ClpX ATP-dependent protease.
Um, S. J., Learn, B. A., Georgopoulos, C., Sliekers, O., Gonciarz-Swiatek, M., Zylicz, M., McMacken, R., Kelley, William, Wawrzynow, Alicja   +8 more
core   +1 more source

Investigating The Role Of ClpP- And ClpX-Mediated Antimicrobial Resistance In Bacillus Anthracis

, 2020
The regulatory ATPase ClpX in Bacillus anthracis contributes to resistance against cell-wall active antibiotics. ClpX can function independently as a chaperone or together with ClpP to form the ClpXP protease.
Zou, Lang
core  

Functional investigation of the two ClpPs and three ClpXs in Myxococcus xanthus DK1622

mSphere
ClpXP is a protease complex that plays important roles in protein quality control and cell cycle regulation, but the functions of multiple ClpXs and multiple ClpPs in M. xanthus remain unknown.
Tianyu Wan, Ying Cao, Ya-jun Lai, Zhuo Pan, Yue-zhong Li, Li Zhuo   +5 more
doaj   +1 more source

ClpX-Mediated Remodeling of Mu Transpososomes [PDF]

Molecular Cell, 2001
Burton, Briana M, Williams, Tanya L, Baker, Tania A   +2 more
openaire   +1 more source

ClpX stimulates the mitochondrial unfolded protein response (UPR^mt) in mammalian cells

, 2015
Proteostasis is crucial for life and maintained by cellular chaperones and proteases. One major mitochondrial protease is the ClpXP complex, which is comprised of a catalytic ClpX subunit and a proteolytic ClpP subunit. Based on two separate observations,
Braun, Thomas, Krüger, Marcus, Wanrooij, Sjoerd,, Ianni, Alessandro, Al-Furoukh, Natalie,, Hölper, Soraya, Nolte, Hendrik   +6 more
core   +1 more source

Alteration of the synthesis of the Clp ATP-dependent protease affects morphological and physiological differentiation in Streptomyces

, 1999
International audienceThe genes of Streptomyces coelicolor A3(2) encoding catalytic subunits (ClpP) and regulatory subunits (ClpX and ClpC) of the ATP-dependent protease family Clp were cloned, mapped and characterized. S.
Viala, Julie, Mazodier, Philippe, Servant-Moisson, Pascale, de Crecy-Lagard, Valerie, Grandvalet, Cosette   +4 more
core   +1 more source

Sequence and transcriptional analysis of clpX, a class-III heat-shock gene of Bacillus subtilis

The nucleotide sequence of clpX, which is localized between the tig (trigger factor) and the ion (ATP-dependent protease) genes at 245\ub0 on the standard Bacillus subtilis (Bs) genetic map, was determined.
Wipat A, Emmerson PT, Hecker M, Harwood CR, Gerth U, Carter N   +5 more
core   +4 more sources

An unexpected role for mitochondrial ClpX [PDF]

Nature Structural & Molecular Biology, 2015
openaire   +1 more source

MecA in Streptococcus mutans is a multi-functional protein

mSphere
Our recent studies have shown that deficiency of MecA in Streptococcus mutans significantly affects cell division, growth, and biofilm formation. In this study, an in vitro mixed-species model, proteomics, and affinity pull-down assays were used to ...
Kassapa Ellepola, Robert C. Shields, Jessica K. Kajfasz, Hua Zhang, Jose A. Lemos, Hui Wu, Zezhang T. Wen   +6 more
doaj   +1 more source

Correction: The Mycobacterium tuberculosis ClpP1P2 Protease Interacts Asymmetrically with Its ATPase Partners ClpX and ClpC1

, 2015
Correction: The Mycobacterium tuberculosis ClpP1P2 Protease Interacts Asymmetrically with Its ATPase Partners ClpX and ...
PLOS ONE (2189197)
core   +1 more source