Results 141 to 150 of about 4,851 (193)

Allosteric inhibition of human mitochondrial ClpP by hijacking the dordaviprone (ONC201) binding site. [PDF]

Nat Commun
Goncalves MM, Uday AB, Watson IDG, Chau AM, Kalhor-Monfared S, Wan B, Kiyota T, Currie SQW, Jitkova Y, Feng Y, Diamandas M, Ling D, Ma M, Mancini RS, Wang Z, Casás-Selves M, Joshi D, Mohammed M, Subramaniam R, Fernandes EL, Yan Y, Pomroy N, Hurren R, Gronda M, Velyvis A, Yudin AK, Reed MA, Prive G, Aman A, Isaac M, Marcellus R, Uehling D, Schimmer AD, Zeytuni N, Vahidi S.   +34 more
europepmc   +1 more source

Identification of a Novel <i>CLPX</i> Variant in a Mixed-Breed Dog with Anemia and Spinocerebellar Ataxia. [PDF]

Genes (Basel)
de Cecco BS, Blake JM, Kim NJ, Coffey MC, Johnston AN, Miller AD, Ekenstedt KJ, Lee J.   +7 more
europepmc   +1 more source

Drug repurposing: antimicrobial and antibiofilm effects of MLS0315771 against Gram-positive bacteria. [PDF]

BMC Microbiol
Xu Z, Tang Y, Ma J, Li P, Wen Z, Yu Z, Bai B, Chen Z, Han S, Hou T.   +9 more
europepmc   +1 more source

Structural insights into the Pseudomonas aeruginosa ClpP1•ClpP2 heterocomplex and its interactions with the AAA+ ClpX unfoldase. [PDF]

Protein Sci
Ghanbarpour A, Zhang JJ, Davis JH, Baker TA, Sauer RT.   +4 more
europepmc   +1 more source

Structural and mechanistic insights into caseinolytic protease inhibition for antimicrobial development against Pseudomonas plecoglossicida. [PDF]

PLoS Pathog
Chen J, Zhang P, Guan H, Gong B, Li X, Li Z, Li F, Zhou B, Chen X, Chen X, Ouyang S, Zhang YA.   +11 more
europepmc   +1 more source

Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation. [PDF]

Nat Commun
Chen W, Lander GC, Yang J.
europepmc   +1 more source

Cell splitting in Staphylococcus aureus is controlled by an adaptor protein facilitating degradation of a peptidoglycan hydrolase. [PDF]

PLoS Genet
Barbuti MD, Skjennum EF, Mebus VH, Morales Angeles D, Hustad M, Mårli MT, Frees D, Kjos M.   +7 more
europepmc   +1 more source

The role of mitochondrial proteases in inflammation and immunity. [PDF]

Front Immunol
Ferreira ARO, Day EA.
europepmc   +1 more source

Identification and validation of reference genes for qPCR of Pseudomonas aeruginosa L10 under varying n-hexadecane concentrations. [PDF]

BMC Microbiol
Wang H, Wang X, Chen J, Zhang Y, Liu J, Xia F, Li J, Wu T, Liu L.   +8 more
europepmc   +1 more source

Self-resistance mechanism to acyldepsipeptide antibiotics in the <i>Streptomyces</i> producer. [PDF]

mBio
Thomy D, Reinhardt L, Liebhart E, Franz-Wachtel M, Maček B, Sass P, Brötz-Oesterhelt H.   +6 more
europepmc   +1 more source