Results 101 to 110 of about 3,616 (191)
NOA1, a novel ClpXP substrate, takes an unexpected nuclear detour prior to mitochondrial import. [PDF]
PLoS ONE, 2014 The mitochondrial matrix GTPase NOA1 is a nuclear encoded protein, essential for mitochondrial protein synthesis, oxidative phosphorylation and ATP production. Here, we demonstrate that newly translated NOA1 protein is imported into the nucleus, where it
Natalie Al-Furoukh +5 more
doaj +1 more source
Advanced Science, Volume 13, Issue 20, 9 April 2026.ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin +9 more
wiley +1 more source
ClpXP degradation of FtsZ polymers.
, 2017 (A) Alexa Fluor labeled FtsZ (24 μM total) was polymerized with GTP (2 mM), where indicated, in the presence of a regenerating system, and then incubated alone, with ClpXP (1.6 μM) and ATP (5 mM) or with ClpX (1.6 μM) and ATP (5 mM).
Joseph Conti (3692128) +3 more
core +1 more source
Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore
Advanced Functional Materials, Volume 36, Issue 15, 19 February 2026.To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul +8 more
wiley +1 more source
MinC competes with ClpXP for FtsZ in vitro.
, 2014 A. MinC was included in degradation reactions containing FtsZ with GTP and ClpXP (0.5 µM). B. FtsZ (5 µM; 125 pmol/reaction) was first preincubated with GTP (2 mM) and then incubated with MinC (2 µM), ClpXP (0.5 µM) and ATP, as indicated.
Leslie Rea (549912) +4 more
core +1 more source
Molecular Plant Pathology, Volume 27, Issue 2, February 2026.Erwinia amylovora infects apple blossoms by activating the T3SS, then spreads systemically via amylovoran‐mediated biofilms. Transitions between motile and sessile states are regulated by key two‐component systems and c‐di‐GMP. This review summarises infection biology, virulence factors, regulatory networks and evolutionary insights underlying fire ...
Dhirendra Niroula +3 more
wiley +1 more source
Highly Dynamic Interactions Maintain Kinetic Stability of the ClpXP Protease During the ATP-Fueled Mechanical Cycle [PDF]
, 2016 The ClpXP protease assembles in a reaction in which an ATP-bound ring hexamer of ClpX binds to one or both heptameric rings of the ClpP peptidase. Contacts between ClpX IGF-loops and clefts on a ClpP ring stabilize the complex.
Sello, Jason K. +4 more
core +1 more source
Frontiers in Molecular Biosciences, 2015 In Escherichia coli, σS is the master regulator of the general stress response. The level of σS changes in response to multiple stress conditions and it is regulated at many levels including protein turnover.
Dimce eMicevski +3 more
doaj +1 more source
FEBS Letters, Volume 600, Issue 1, Page 83-98, January 2026.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
ClpXP Modulates Cell Growth and Morphology in Cell Shape Mutants of E.coli [PDF]
, 2014 ClpXP modulates cell growth and morphology in cell shape mutants of E. coli Ryann Murphy1 and Jodi L. Camberg1 1University of Rhode Island, Department of Cell and Molecular Biology, Kingston, RI, 02881 Penicillin Binding Proteins (PBPs) are a family of ...
Murphy, Ryann
core +1 more source