Results 61 to 70 of about 26,517 (143)
Helicase binding to DnaI exposes a cryptic DNA-binding site during helicase loading in Bacillus subtilis [PDF]
, 1981 The Bacillus subtilis DnaI, DnaB and DnaD proteins load the replicative ring helicase DnaC onto DNA during priming of DNA replication. Here we show that DnaI consists of a C-terminal domain (Cd) with ATPase and DNA-binding activities and an N-terminal ...Shi, Wei, Zakharova, M., Klaas Krab, Sawasdichai, Anyaporn, Heidar-ali Tajmir-riahi, Lee, Sang Yup, Largaespada, DA, Lee, TMH, Bogdanova, E., Poe, Jonathan C., Cencini, M., Hamamori, Yasuo, Ivic, Nives, Nolan, Matthew J., Georgiadis, Rosina M., Fox, Keith R., Eyras, E, Schumann, G., Anstey-Gilbert, C.S., Langford, Cordelia F., Srimasorn, S., Liliana E. Layer, Roepcke, Stefen, Smith, C., Peter Whitfield, Matthew J. Nolan, Goodfellow, I., Lisa J. Garrett, K. M. Ko, Goumas, G, Panagiota Kafasla, Verhoeven, Stefan, Campbell, D.S., Parker, Brian J., Hodskinson, MRG, Stephan A. Hahn, Geoff Kneale, Barann, M., Dehghani Amirabad, A., Martin Holcik, Yu, F., Klimešová, K., Zhang, S., Tateishi, Satoshi, Chamovitz, Daniel A., Shi, W., Liu, Ching-Ti, Smith, Corinne J., Van den Berghe, Bram, Juan J. Bonfiglio, Barsh, G., B. P. Anton, P.-S. Jayaraman, Shao, W., Gundersen, S., Hatfull, Graham F., Lipowsky, R. ; https://orcid.org/, Ternette, N, Steenackers, H., Shochot, Lea, Hyungjin Kim, Prindl, Konstantin, Chua, J., Martin F. Lavin, Lima Mendez, Gipsi, Gasser, Robin B., Boris Adryan, Yao, D., Wanwan Ge, Main, Bradley J., James E. Taylor, Sand, Olivier, Miller, Marshall G, Wen, Jiayu, van Heel, Auke J., Karl-Peter Hopfner, Rodnina, M., S. L. Salzberg, Pirovano, W., Kim, J., Smith, CW, Pascal Lefevre, Dheghani Amirabad, A., Fomin, Marina E., Lacroix, C., Chang-jiun Wu, Kuipers, Oscar P.; id_orcid, Thoms, JAI ; https://orcid.org/, Shao, W, Schaeffer, Patrick M., Robinson, Sophie, Desai, Siddhi, Scarlett, Garry, Ivanova, Darja, Jayaraman, P.-S., Fays, F, Will, Hans, CAMARGO, Anamaria A., Kapeli, K., Wolf, Lauren K., Yu, J., REN, Bing, Lilley, D., Nakatani, Kazuhiko, Severinov, K., Lapinaitė, A., Yosef Shiloh, Christopher S. Anstey-gilbert, Markus Meier, Ryan M Layer, Hutchins, Lucie N., Cyrille Girard, Chan, Yuk Hang, Charbonneau, David M., Bulyk, Martha L., Ahdash, Z., Klára Klimešová, Roberts, Richard J., Baakman, Coos, Chen, Chunnuan, Stuart R. W. Bellamy, S. Letovsky, Jakob, B., Larsson, Jonas, Hughes, G., Bonifer, C., Osmani, Lais, Pereira da Silva, Luis, Crane-Robinson, Colyn, Chandrashekran, A, Cindy L Will, Perreault, C, Huang, Y ; https://orcid.org/, Caliskan, Neva, Feder, M., Wodak, Shoshana, Ruprecht, Colin, Montalban-Lopez, Manuel, Cruz-García, Andrés, McKay, Bruce C., Wildner, Gerhild, Yang Gao, Sprengel, Rolf, Zhang, Xiang-Sun, Serena Li, Reading, Dr Eamonn, Faith, Jeremiah J., BRENTANI, Ricardo R., Nigam, R, Dirk Heckl, Bellora Pereyra, Nicolás, Chiu, Tsu-Pei, Sabine Knoess, Svetlana E. Sedelnikova, Gerald G. Schumann, Friedeberg, C., Michael T Wolfinger, Smerdon, S.J., Nielsen, P., Henderson, Charlotte, Marty, Regis, Tremethick, D., Mantouvalou, E, Isa, I., Isa, IM, Soong, T., Ferrari, Camilla, Robertson, Adam B, Hagie, F., Raleigh, Elisabeth A., Varga, A., Jex, Aaron R., Zhang, X., Yang, Lisong, Rossi, S., MacKenzie, KL ; https://orcid.org/, Yubing Liu, Jex, AR, Merkina, EE, Joe Mellor, Pei, Xue-Yuan, NAVARRO, Fabio C. P., Kinston, Sarah J., Adams, F., Yuan, Shinsheng, Zabet, Nicolae Radu, A. Borrmann, Qingge Li, Rajgor, Dipen, Chan, Denise So Bik, Shaw, Pang Chui, Gooding, C, Van Vlierberghe, P, Sobott, F., Cantacessi, Cinzia, LEVY, Samuel, Adrian Schwarzer, Lelieveld, Stefan H., Zhang, YY, P. Kafasla (7649141), Grosjean, H., Dalamagas, T, Arlehamn, C., David M. Charbonneau, Brockman, J. Michael, Souquet, M., Zainab Ahdash, Driscoll, Michael E., Paul Dyson, Sobott, Frank, Byrne, RT, Giannopoulos, G, Fang, Y., Reiss, Bernd, Robert M Winston (16266224), Retkute, R, Shukla, Anshuman, CUFF, Alison L., Leontis, Neocles B., Elcie Chan (736765), Feltham, Jack, SILVA NETO, Jose F. da, Kijas, Amanda W., Byrne, R., Manjasetty, Babu, Ellis, P, Christian Roth, Heyduk, Tomasz, Ekaterina Protozanova, Lefevre, P., M. Llorian (7649144), Ji, ZL, Dibb, NJ, Martín-Subero, José Ignacio, Koppstein, David Neal Pira, Kloss-Brandstatter, Anita, Seung Y Rhee, Sherratt, David, Uzma Islam, Schaeffer, Mary, NICOLAS, Marisa F., Wolski, W., Swings, T., Roy, B., Smith, Christopher, W. J., Fox, K.R., Jovin, T., Huang, H., Taylor, Toni, Schofield, L, Kalam, M. Abul, Dibb, N., Simon, E., Peter D. Cary, Klungland, Arne, Rami Khosravi, Naume, Bj., Boris Simovski, Dimitrova, Nevenka, Kabsch, W., Zhang, Mingjie, Couche, Fabian, Hayete, Boris, Chandra, G., Alexander Favorov, Proost, Sebastian, Guleria, Jyotsna, Kåre Lehmann Nielsen, Chen, Y. Z., Reiser, L., Garner, I., Gueven, Nuri, Keith F. Chater, Hellen, Christopher U.T., Li, X., Titgemeyer, F., Blundell, TL, Christopher W.J. Smith, Luisi, B.F., Tripathi, P, Nicholas E. Dixon, Bernd Epe, Tremethick, DJ, Bettler, E.J.M., Nielsen, M., Schoolnik, Gary K., Greaves, I., Tan, Geok Chin, Wong, JWH ; https://orcid.org/, Nadja C. de Souza-Pinto, Will, H., McGettrick, Mark G., Christopher W. J. Smith, Andy M. Lau, Leonore Reiser, Schäfer, Florian, Abubucker, S, Marks, P., Makedonka Mitreva, Cai, CZ（Bioinformatics and Drug Design Group, Department of Computational Science, National University of Singapore, Blk SOC1, level 7, 3 Science Drive 2, Singapore 117543,）, Scott, H., Li, Ker-Chau, Medema, M.H., Mantouvalou, E., David R. Lancia, Klusmann, Jan-Henning, Bjørås, Magnar, Fiammengo, R., Zirbel, Craig L., Emmanuelle M Charpentier, Zaini, Mohamad A., Li, QG, Gasparoni, N., Dahl, John Arne, Metzler-Nolte, N., Roth, Christian, Holtkamp, Wolf, Gasser, Robin B, Feenstra, K.A., Pirovano, Walter, Ivan Matic, L. Osmani, Peter J. Mckinnon, Nakatani, K., Larson, Lisa, Brown, T, Zingler, N., Scott, HS, Heringa, Jaap; id_orcid, Xue, Hong, Jessica L. Wojtaszek, Epe, B., Yup Lee, S., R. M. Pokrzywa, MELLO, Barbara P., Herrera, M., Marcellus, Kristen A., Thiruma Valavan Arumugam, GARRATT, Richard Charles, Alan D. D’andrea, Tatewaki, Naoto, Heckl, Dirk, Lars Schomacher, Mercereau−Puijalon, O., Mary Schaeffer, Jan Michiels, Hall, RS, Nolan, MJ, P. Noy, John McGeeghan, Ryan, Joseph F., Marintchev, Assen, Herrera, MC, Krokan, Hans Einar, Rammensee, H.G., Paradela, A., Heckel, A., Schofield, L., Cai, C. Z., Lefevre, P, Harris, C. Jake, Schmidt, F., Firth, A.E., MacKenzie, Karen L., Michael Hiller, Stein, Lincoln, Doreen Ware, Smith, Adam de, Tognetti, S., Skovgaard, Ole, Rudolph, Christian J., Vincent, H., Jennifer Beane, Zhu, G, Els, C.A.C.M. van, Langlois, Marc-André, Suckling, Colin J., Elisabeth Sonnleitner, Zhao, Bo Tao, Hopfner, K., I. Mickleburgh (7649138), EDSALL, Lee, Lammens, K., Laurent Kreplak, Burkhard Jakob, Adriana Roithová, Layer, L., Volinia, S., Weith, A., Gholam Khodakaramian, Stüetzer, A, Hopfner, Karl-Peter, Meister, G., Bassani-Sternberg, M, Lauren K. Wolf, Taylor, James E., Khanna, Kum, Polansky, J., Fusser, Markus, Kahane, Bernard, Smith, CWJ, Feltham, J, Wiencke, John K., Nishida, Hiroshi, C. Cheng Kao, Fernholz, Doris, Yann Thomas, Pankaj Jaiswal, C. Karlsson, Cheng, JP, STRAUSBERG, Robert L., Simone Pigolotti, Seeburg, Peter H., Bassani-Sternberg, M., Marto, Jarrod A., Bram Van Den Bergh, Buff, M.C.R., GALANTE, Pedro A. F., Söding, J., Scholz, J., Dimude, JU, Basu, Ashis K., Gianmoena, K., Vanderstocken, Gilles, Schulz, M.H., Salas Ellacuriaga, Antonio, Klusmann, J., Altmueller, J., Wagner, Gerhard, Boddy, Christopher N, Barman, T., Kahane, B., Weichenrieder, O. ; https://orcid.org/, Chen, Junjie, Negri Martínez, Ana, PARMIGIANI, Raphael B., LEWIS, Tony, Ulrich Kück, Cross, J., Konstantin Prindl, Oliver Weichenrieder, Dan Halperin, TOJAL, Israel, Fisk, NM, Brohée, Sylvain, Lüttges, J., Watson, James A., Adam B. Robertson, Araki, Kimi, Vriend, Gerrit, Flemming, CS, Kottmann, Renzo, Wulffen, Bernhard, Kinkel, Sarah A., Colin Ruprecht, Nuzhdin, Sergey V., Politis, A, A W. Kijas, von Lindern, Marieke, Witzemann, V., Fisk, N., Paul Mcdermott, Gasparoni, G., Martin Turner, Moriya, Maasaki, Zhou, Mi, Dmytro Titov, Jin, You Xin, Sillitoe, I., Thornton, Janet M., Langsley, G., Rachlin, John, Ranganathan, Shoba, Sengupta, Sugopa, Wong, Y., Blais, Alexandre, Ascher, David Benjamin, Sherratt, David J, Vaughan, K, SOUZA, Sandro J. de, Meister, G, Zheng Wang, Vejsadova, S., Main, Bradley, Specht, Gunther, Layer, R., Young, Neil D., Dimitrova, N., Dmitry Cherny (2698555), Yang, Lin, Weel-Sneve, Ragnhild, de Souza-Pinto, Nadja C, Du, D., Matić, I., Stuart, Joshua M., SILLITOE, Ian, Guille, Matt, Riggs, Michael, Paul W. Sternberg, Kostas Repanas, D. Graham, Lee, KM, Isa, Iihsan Mad, Pascale V Guillot (16266218), Katyal, Sachin, Guillot, Pascale V., Metayer, Catherine, Dominguez-Malfavon, L., MacKenzie, Karen L, Ian G. Goodfellow, Arlehamn, CSL, Hall, Ross S., Çukuroğlu, Engin; Gürsoy, Attila ; Keskin, Özlem, Klöppel, G., Nick M Fisk (16266221), Schreiter, P., Magara, Taku, Mitreva, Makedonka, Guillotte, Micheline, Shi, Yi, Schmid, E, DeCaprio, Dave, Li, Wei, Urbanavičiūtė, G., Sandor Vajda, van Veelen, P.A., Yael Ziv, Andrés León, Eduardo, Yie Liu, Hopfner, K-P, Ge, W., Heinitz, C., Kuipers, Oscar P., H.-P. Choi, Myers, F.A., RAMALHO, Rodrigo F., Sponer, J, Li, Minghui, Lionne, Corinne, Gardner, Timothy S., Bharathi Reddy Kunduru, Malone, B., Vujaklija, Dusica, Rammensee, H., Mutwil, Marek, Proost, S., Roberts, Daniel S., Van den Bergh, Bram, Castellano, L., David M. Wilson, Meister, Gunter, Tegge, Allison N, OHNO-MACHADO, Lucila, Napthine, S., Brown, T., P. D. Cary, Ma, Shiyong, Anuradha Pujar, Xiaoyan Lin, Zhao, Y, Schlicht, M., Aeschimann, F., Oliveira, L., Mehrjouy, Mana M., Wolfinger, M., Pradhan, Sriharsa, Zhao, X., Zhong, Ling, Sawasdichai, A., Pires, Douglas Eduardo Valente, Claudia S. Flemming, Baulcombe, David, Stephan Diekmann, Schlapbach, R, Fays, Frédéric, Beck, D, Benini, L., Oakley, Greg, Garcia-Mena, J., Hovig, Eivind, Donglin Liu, Cary, Peter, Geir K Sandve, Cheng, Jianlin, Clinton C. Macdonald, Upton, AL, Van de Walle, Inge, Wojtaszek, Jessica L, Nardini, C., Medema, M., Weber, Tilmann, Anja Joachim, III, David M. Wilson, Vishal Shah, Koh, J., Bossini-Castillo, L., Caron, E., Papapanagiotou, Ioanna, Tremethick, D.J., Kasif, Simon, Roth, C., Hua Huang, Koehrsen, Michael, Huang, Chia-Ling, Cabrita, Miguel A., Shukla, A., Northaft, H., Ruth Nussinov, Yu, Yingpu, Li, Bibo, Bell, JB, Pimanda, John E., Lucito, R., Melissa R. L, Hengstler, J., K. Gaston, Perreault, C., de Jong, Ineke, Deutsch, E.W., Hilton, DJ, Lim, Yi Chieh, Marco Tejón, Esther, Xia, Yu, Yakovchuk, Peter, Schneider, Stephen J., Lund, Anders H, Meijgaarden, K., Wolvetang, Ernst, Klinger, Bertram, Pires, DEV, Epe, Bernd, Malartre, Marianne, Ilic, Katica, Cherry, A. L., Stahl, H., Anja Kiesel, Christoph Bock, Callaghan, Anastasia, Ottenhoff, T., Sachs, Martin, Yang, Jian, Meijgaarden, KE, Robinson, S, Wu, Qinglin, Guo, Li Tao, Savoie, Mathieu, Chih-Wei Tung, Shiloh, Yosef, Schmid, E., Hana Imrichová, Mobli, Mehdi, Avraham, S., Wang, Yan, Šponer, Jiri, SIMPSON, Andrew J. G., Vincent, Helen A., Dimude, Juachi U, Sridhar, Sriram, Wenhao Jin, Nielsen, M, Montalbán-López, Manuel,, Constanze Bonifer, Buff, Maximilian, Booth, PJ, Dixon, Ray, Ji, Z. L., SOUZA-PINTO, Nadja C. de, Luisi, Ben F., Swaminathan, Rajeswari, Reddy, Timothy E., Yeo, G., Resch, Armin, Meier, Markus, Anstey-Gilbert, Christopher S., Tajmir-Riahi, Heidar-Ali, Pan, Elysia, Tognetti, S, Alexieva, D., SALIM, Anna Christina M., McGeehan, John, Admon, A., Thresh, Sarah, Wilfried Kramer, Nandi, Soumyadeep, Winston, R., Costello, C., Flemming, Claudia S., Garratt, R., J. Cheng, Borrmann, Annika, Alexandra Stüetzer, Pei, X.Y., King, Glenn F., Fusaro, Vincent A., Kendall, J. T., Pacher, Dominic, Wang, Q., Sinner, E., Shuchen Zhang (1563844), Kenneth W. Fishbein, Jayaraman, Padma-Sheela, Gueven, N., Winston, RM, Campagne, F., Wong, KB, Booth, P., Costello, CE, Shah, Vishal, Sakmann, B., Glyn R. Hemsworth, Knoess, Sabine, Meijgaarden, K.E., Llorian, Miriam, N. Klitgord, Cruz García, Andrés, Scurtescu, C., Sriram Sridhar, Jin, W., Delisi, Charles, Soultanas, P, Nolan, M.J., Lukinavičius, Gražvydas,, Reading, E, Kok, Jan,, Klimašauskas, S., Jerome S. Brody, Tsanakas, P, S. D. Streeter, Vingron, Martin, Sergio Pulido-tamayo, Nakken, Sigve, Kurz, Thimo, Phillips III, J. A., Waigh, R.D., Jing Zhang, Bellamy, SRW, Gooding, Clare, Li, Xiaohua, Aebersold, R, Hilton, D., Eickholt, Jesse, Christophe N. N’soukpoé-kossi, Trynka, G., Obarska, A., Ng, David M., Rosales Gerpe, María Carla, ABRANTES, Eduardo F., Pestova, Tatyana V., Mao, Maria, Ball, Neil J., Lemer, C, Raftery, Mark J, Van Vlierberghe, Pieter, Sinner, E. K., Stolte, Christian, 李庆阁, Alexieva, Diana, Errington, N., Couture, Jean-François, Porschke, D., Scott, Hamish S., Wang, Yong, Riera, A., Orengo, C.A., Brors, B., Chen, Lihong, Scherf, Artur, Dustin Holloway, Jesse Eickholt, Hong, Peng, Adryan, B, de Jong, Anne; id_orcid, Heckel, Alexander, Nick J Dibb (16266227), Gaston, Kevin, Rosenstiel, P., Lucy Thorne, Allain, Frederic, Charikleia Ioannou, Winston, Robert M., Abdou, Laetitia, C. W. Smith (7649147), YE, Zhen, Wang, Su, Khan, Sohail, Pulido Tamayo, Sergio, Chan, DSB, Hemsworth, Glyn R., LIU, Yie, Stillman, Timothy J., Vizcaino, J.A., Jin, Qi, Fedorova, O.S., Ian Greaves, Xu, Derrick, Cohen-Karni, Devora, Ranganatha, Shoba, Ule, Jernej, Reitzel, Adam M., Hallegger, Martina, Marchal, Kathleen, Nielsen, K. L., Klomp, Jan, Hall, R.S., Sternberg, Paul W, Pigolotti, S., Riggs, M., Hellen, Christopher U. T., Arne Klungland, Krab, K., Tsai, Y-C., Shaw, PC, Thibault, P, Chikina, M., Nathan C Sheffield, Ware, D. H., Lipowsky, R., Jan-Henning Klusmann, R. J. Jackson (7615025), Sze, KH, Alexandre Blais, Will, C., Vincent, L., Koenen, M., Vajda, Sandor, Juan, David, Ladiges, Warren C, Mallilankaraman, K., Liang, JX, Toon Swings, Pokrzywa, Revonda M., Smyth, G., Smith, SL, Leung, Siu Kai, Gertraud Burger, Pfander, S., Stanek, D., Ternette, Nicola, Graber, Joel H., Souza, G.A. de, Rüther, Ulrich, Geok Chin Tan (7461980), Kunduru, B R, Dass, Brinda, Fröhler, S., Walter Pirovano, Xiao, Jianqiao, Khurshid, T, Nicolae Radu Zabet, Anna M. Heidenblut, Weiner, Brian, Sarah Lissenden, Sarkar, R., Börnigen, Daniela, Matsumoto, Saki, Sanders, M.P.A., Eyras Jiménez, Eduardo, Lührmann, R., Rhee, S. Y., Bandelt, Hans-Jürgen, Zubarev, RA, Derynck, R., Katyal, S., Phillips, J., S. Curry (7485314), Raftery, Mark J., Bartel, David, Stone, Carlanne, Knezevic, Kathy, T. Magara, Hamann, A., Fernández Ávila, María Jesús, Pedrioli, P., Sharma, V., Stevens, P., Unbehaun, Anett, Smyth, GK, Thomas, Yann, J. A. Dougan, Chan, E., Cuff, A.I., Katannya Kapeli, Stein, L. D., Medema, Marnix H., Baulcombe, D., Sherlock, Gavin, Pimanda, John E, Zubarev, R., ZAGO, Marco Antonio, R. J. Roberts, Housman, Genevieve, Demidov, Vadim V., Skovgaard, O, Muench, Marcus O., Fiziev, P., de Jong, Anne, Clarke, P., Wong, Jason WH, Bhutkar, Arjun, Felder, B., De Jong, IDE, Felix F Adams, Wilson, Geoffrey, Gondeau, C., Jong, Anne de,, Han, L. Y., Jaiswal, P., L. Oliveira, Gene W Yeo, Sherratt, DJ, Kanehisa, Minoru, Rachlin, John N., Garry Scarlett, Maxim D. Frank-kamenetskii, Hemsworth, G.R., Wong, Jason W H, Evrin, C, Wang, Yun, de Souza, GA, Zhenjun Hu, Gao, Yanzhe, Kolupaeva, Victoria G., Cordelia F Langford (16266215), Schuster, H, de Souza, G., de Graaf, Carolyn A., SOUZA, Jorge E. S. de, Isa, Ihsan Mad, Sisakova, E., Holloway, Dustin, KIRKNESS, Ewen F., Benson, Gary, Gelfand, Yevgeniy, Peng, C., Cosgrove, Elissa J., Temple F. Smith, T. Dafforn, Aaron R Quinlan, Schuster, H., Djordjevic, M., Kaufmann, S., Juhn, Frank S., Joachim, A, Ellis, Peter, Vlieg, J. de, Reading, Eamonn, Mellor, Joe, Tan, G., García-Jiménez, Beatriz, Seeburg, P. H., Star, Ayelet, Anil Chandrashekran (14915766), Nitzberg, Michael, Karlsson, Camilla, Rudolph, Christian J, Murata, A., Macaskill, A., Aebersold, R., Marion, P., Matsumoto, S., Lavin, M. F., Ulrike Herbr, Weiserova, M., Shoba Ranganathan, Kauppinen, Sakari, Wolfinger, Michael T., Gelinas, R., Pei Zhou, Protozanova, Ekaterina, Barsh, G. S., Mullikin, James C., Lea Shochot, Blin, K., S. Kasif, Cui, Wei, Booth, Paula Jane, Koziris, N, Ma, S, Conway, Kyle R, James P. J. Chong, Oliveira, Laerte [UNIFESP], Hayflick, J., Li, Zhiguo, Yang, Xiao, Becherel, O.J., Parker, Stephen C.J., Blin, Kai, Upton, Amy L., Fang, Ying, Akalin, A., Ravid, Katya, Mehrjouy, Mana M, Miriam Llorian, Haase, N., Sette, A, C. Smith, Sandve, G., Kneale, Geoff, Tan, GC, Bell, S. +999 morecore +49 more sourcesLPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT
Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang +4 morewiley +1 more sourceInhibin βB Mediates Oligotrophic Adaptation via Regulating Muscle Satellite Cell Proliferation and Differentiation in Schizopygopsis younghusbandi
Integrative Zoology, EarlyView.① Nutrient deficiency upregulates inhibin βB, activating SMAD signaling to promote p21. Increased p21 inhibits mcm2/mcm4/mcm5 and cyclin E2, inducing G1‐phase arrest, slowing growth, and reducing energy consumption.
② Inhibin βB also upregulates pdgf‐c, which induces α‐SMA, leading to muscle satellite cell fibrosis.Weiqiang Li, He Gao, Chaowei Zhou, Luo Lei, Junting Li, Chao Ma, Zitu Ma, Mengwei Yao, Kexin Ma, Yunpeng Xiang, Yan Zhou, Yongrui Lu, Da Ji, Minghong Wei, Luohao Xu, Zhaofang Han, Haiping Liu +16 morewiley +1 more sourceCryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate
Nature Communications, 2016 The Cdc45-MCM-GINS (CMG) helicase unwinds DNA during replication, a process that requires the ATPase-dependent activity of the MCM complex. Using cryo-EM reconstructions of the CMG complex in different conformations, the authors propose a model where the Ferdos Abid Ali, Ludovic Renault, Julian Gannon, Hailey L. Gahlon, Abhay Kotecha, Jin Chuan Zhou, David Rueda, Alessandro Costa +7 moredoaj +1 more sourceExpanding Phenotype of GINS1 Deficiency: A Case Report and Review of the Literature
Clinical Genetics, Volume 109, Issue 6, Page 1076-1080, June 2026.The authors present a novel case and review of individuals with GINS1 deficiency, causing severe growth restriction and combined immunodeficiency. Only the ninth case of this ultrarare disorder, it highlights the role of these variants in disease, glaucoma as a feature, and the possibility of immunodeficiency without infections in affected individuals. Michael P. Mackley, Rae Brager, Hannah Geddie, Vicky Breakey, Rebecca Hough, Dimitrios J. Stavropoulos, Vanda McNiven +6 morewiley +1 more source
