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DNA Helicase–Polymerase Coupling in Bacteriophage DNA Replication [PDF]
Viruses, 2021 Bacteriophages have long been model systems to study the molecular mechanisms of DNA replication. During DNA replication, a DNA helicase and a DNA polymerase cooperatively unwind the parental DNA.
Chen-Yu Lo, Yang Gao
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Inhibitory effects of anthracyclines on partially purified 5′–3′ DNA helicase of Plasmodium falciparum [PDF]
Malaria Journal, 2022 Background Plasmodium falciparum has been becoming resistant to the currently used anti-malarial drugs. Searching for new drug targets is urgently needed for anti-malarial development. DNA helicases separating double-stranded DNA into single-stranded DNA
Pongruj Rattaprasert +4 more
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The Vaccinia Virus DNA Helicase Structure from Combined Single-Particle Cryo-Electron Microscopy and AlphaFold2 Prediction [PDF]
Viruses, 2022 Poxviruses are large DNA viruses with a linear double-stranded DNA genome circularized at the extremities. The helicase-primase D5, composed of six identical 90 kDa subunits, is required for DNA replication.
Stephanie Hutin +6 more
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EMBO Journal, 2012 Mcm10 is essential for chromosome replication in eukaryotic cells and was previously thought to link the Mcm2‐7 DNA helicase at replication forks to DNA polymerase alpha.
Sugopa Sengupta +2 more
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Implications of Membrane Binding by the Fe-S Cluster-Containing N-Terminal Domain in the Drosophila Mitochondrial Replicative DNA Helicase [PDF]
Frontiers in Genetics, 2021 Recent evidence suggests that iron-sulfur clusters (ISCs) in DNA replicative proteins sense DNA-mediated charge transfer to modulate nuclear DNA replication.
Minyoung So +8 more
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History of DNA Helicases [PDF]
Genes, 2020 Since the discovery of the DNA double helix, there has been a fascination in understanding the molecular mechanisms and cellular processes that account for: (i) the transmission of genetic information from one generation to the next and (ii) the remarkable stability of the genome.
Brosh, Robert M., Matson, Steven W.
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