Results 131 to 140 of about 19,252 (225)

Protective effect of Co-enzyme Q10 on seizure, short term spatial memory and oxidative stress in induced-epileptic rats

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: Temporal lobe epilepsy is the most common type of epilepsy in human. Patients suffer from spontaneous seizures and memory deficiency.
Baluchnejadmojarad T, Roghani M
doaj  

AAD-2004, a potent spin trapping molecule and microsomal prostaglandin E synthase-1 inhibitor, shows safety and efficacy in a mouse model of ALS [PDF]

open access: yes, 2010
While free radicals and inflammation constitute major routes of neuronal injury occurring in neurodegenerative diseases, neither antioxidants nor nonsteroidal anti-inflammatory drugs (NSAIDs) have shown significant efficacy in human clinical trials.
Bok Yun   +12 more
core   +1 more source

Soil Microbial Communities Adjust Thermal Traits and Carbon Allocation in Response to Climate Manipulations in Subtropical Forest and Cropland

open access: yesGlobal Change Biology, Volume 32, Issue 4, April 2026.
Warming increases warm‐adapted microbial taxa and shifts microbial thermal traits toward higher minimum temperature. These adaptations reduce modeled annual soil CO2 emissions by 36%, indicating that microbial thermal trait integration is essential for predicting soil carbon responses to climate change.
Carla Cruz‐Paredes   +7 more
wiley   +1 more source

Schwann Cell TRPA1, a Proalgesic Ion Channel, Mediates Neuroinflammation and Fibromyalgia‐Associated Behaviours in Mice

open access: yesJournal of Neurochemistry, Volume 170, Issue 4, April 2026.
Cellular and molecular mechanisms contributing to TRPA1‐mediated mechanical and cold hypersensitivity and peripheral neuroinflammation in the reserpine‐induced experimental fibromyalgia model. (1) Macrophage‐originated reactive oxygen species (ROS; purple dots) target the transient receptor potential ankyrin 1 (TRPA1) channel localised in Schwann cells.
Evelyne Silva Brum   +7 more
wiley   +1 more source

Myasthenia gravis following the initiation of statin therapy: A multinational self‐controlled case series study

open access: yesJournal of Internal Medicine, Volume 299, Issue 4, Page 502-514, April 2026.
Abstract Background Evidence regarding the risk of new‐onset myasthenia gravis (MG) following statin therapy initiation is limited. Objectives To investigate this potential adverse effect using multinational real‐world population‐based data. Methods A self‐controlled case series (SCCS) study was conducted using electronic medical records and claims ...
Vincent Ka Chun Yan   +16 more
wiley   +1 more source

A scoping review on natural cholesterol lowering supplements sold in South African pharmacies

open access: yesHealth SA Gesondheid: Journal of Interdisciplinary Health Sciences
Background: Dyslipidaemia is defined as elevated total or low-density lipoprotein (LDL) levels or low levels of high-density lipoprotein (HDL). Patients may often make use of natural cholesterol lowering supplements (NCLSs) available at the pharmacy ...
Hyeon Bok Lee   +3 more
doaj   +1 more source

CO-Enzyme Q10 Modulates Semen Parameters in Diabetic Male Rats on Combined Anti-Retroviral Therapy

open access: yesScholars Journal of Applied Medical Sciences
Infertility affects roughly one in six couples worldwide, with male reproductive health increasingly compromised by chronic illnesses, environmental stressors, and pharmacological interventions. Human immunodeficiency virus (HIV) and its treatment with combination antiretroviral therapy (cART) are known to negatively impact male fertility, while ...
Robinson Ohanador   +2 more
openaire   +1 more source

Cardioprotective effects of CoQ10 in pediatric patients with lysosomal storage disorders

open access: yesItalian Journal of Pediatrics
Background Lysosomal storage disorders (LSDs) result from an accumulation of specific substrates, due to the inability to break them down leading to cellular dysfunction in multiple organs, including the heart constituting an important and treatable ...
Yasmine Abuzaid   +5 more
doaj   +1 more source

Coenzyme Q10 mitigates monosodium glutamate-induced hepatic damage: Enzymatic and histological insights from a rat model

open access: yesEndocrine and Metabolic Science
Background: Monosodium glutamate (MSG) is a widely used food additive consumed daily through dietary sources. Regulatory agencies such as JECFA, FDA, and EFSA have established an acceptable daily intake (ADI) of 30 mg/kg body weight/day (expressed as ...
Elahe Ershadifar   +2 more
doaj   +1 more source

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