Results 51 to 60 of about 16,526 (214)

Crystals as Rockets: Modulation of the Salient Temperature in Cocrystals by Solvent Mixture Composition

Angewandte Chemie, EarlyView.
Compositionally engineered mixed solvated cocrystals enable modulation of thermosalient actuation. Guest ratio controls thermosalient temperature and propulsion intensity, providing a tunable platform for designing crystalline systems that exhibit stimuli‐responsive mechanical motion.
Ernesto A. Hernández‐Morales, Dayra Barreto‐Hernández, Dazaet Galicia‐Badillo, Rubén A. Toscano, M. Elena García‐Aguilera, Braulio Rodríguez‐Molina   +5 more
wiley   +2 more sources

Continuous Manufacturing of Cocrystals Using 3D-Printed Microfluidic Chips Coupled with Spray Coating

Pharmaceuticals, 2023
Using cocrystals has emerged as a promising strategy to improve the physicochemical properties of active pharmaceutical ingredients (APIs) by forming a new crystalline phase from two or more components.
Aytug Kara, Dinesh Kumar, Anne Marie Healy, Aikaterini Lalatsa, Dolores R. Serrano   +4 more
doaj   +1 more source

Theoretical study of BTF/TNA cocrystal: Effects of hydrostatic pressure and temperature

Defence Technology, 2015
Cocrystallization is a promising technique for the design and preparation of new explosives, and the stability of cocrystal is highly concerned by the researchers.
Peng-yuan Chen, Lin Zhang, Shun-guan Zhu, Guang-bin Cheng   +3 more
doaj   +1 more source

Improved Manufacturability and In Vivo Comparative Pharmacokinetics of Dapagliflozin Cocrystals in Beagle Dogs and Human Volunteers

Pharmaceutics, 2021
Dapagliflozin (DAP), which improves glycemic control in patients with type 2 diabetes mellitus, has poor physical properties against heat and moisture, thus hindering its manufacturing potential.
Sangho Cho, Jeongwook Lee, Yongwon Yoo, Minyong Cho, Seil Sohn, Beom-Jin Lee   +5 more
doaj   +1 more source

Air-Stable Cyclohexasulfur as Cocrystal [PDF]

Crystal Growth & Design, 2012
A new stable cyclohexasulfur (cyclo-S6) was discovered in the crystal of 3,5-diphenyl-1,2,4-dithiazol-1-ium (dpdti); dpdti was synthesized via an oxidation reaction of thiobenzamide with iodine in ...
Kunihisa Sugimoto, Hiroshi Uemachi, Masahiko Maekawa, Akihiko Fujiwara   +3 more
openaire   +1 more source

Combining a Drug and a Nutraceutical: A New Cocrystal of Praziquantel and Curcumin

Crystals
This study explores the co-crystallization between the drug praziquantel (PZQ) and the nutraceutical curcumin (CU). The investigation revealed two novel solid forms: a cocrystal solvate with ethyl acetate and a non-solvated cocrystal.
Camila Caro Garrido, Marie Vandooren, Koen Robeyns, Damien P. Debecker, Patricia Luis, Tom Leyssens   +5 more
doaj   +1 more source

Cocrystal construction between the ethyl ester with parent drug of diclofenac: structural, stability, and anti-inflammatory study

Heliyon, 2019
This study aimed to collect the crystallographic data of ethyl diclofenac and discover a cocrystal from this ester with its parent, diclofenac acid, and to investigate their physicochemical properties and anti-inflammation activity.
Ilma Nugrahani, Dwi Utami, Yuda Prasetya Nugraha, Hidehiro Uekusa, Rahel Hasianna, Aisyah Amalia Darusman   +5 more
doaj   +1 more source

Machine-Learning-Guided Cocrystal Prediction Based on Large Data Base

Crystal Growth & Design, 2020
A machine-learning model trained on the whole Cambridge Structural Database was developed to assist high-throughput cocrystal screening.
Dingyan Wang, Zeen Yang, Bingqing Zhu, X. Mei, Xiaomin Luo   +4 more
semanticscholar   +1 more source

Preparation and Characterization of a Novel Cocrystal of Atorvastatin Calcium with Succinic Acid Coformer

Indonesian Journal of Chemistry, 2019
Preparation and characterization of a novel cocrystal of atorvastatin calcium with succinic acid coformer were successfully performed. This research aims to modify the crystalline form of atorvastatin calcium through cocrystallization with succinic acid ...
Yudi Wicaksono, Dwi Setyawan, Siswandono Siswandono, Tri Agus Siswoyo   +3 more
doaj   +1 more source

Synthesis and Characterization of a (−)-Epicatechin and Barbituric Acid Cocrystal: Single-Crystal X-ray Diffraction and Vibrational Spectroscopic Studies

ACS Omega, 2021
The paper presents the contribution of the cocrystallization method in the physicochemical modification of catechins that exhibit low oral bioavailability.
Iwona Budziak-Wieczorek, U. Maciołek
semanticscholar   +1 more source