Invited for this month's cover picture is the group of Professor David Bryce at the University of Ottawa. The cover picture shows a stylized depiction of the mechanochemical halogen‐bond induced cocrystallization of 3‐iodoethynylpyridine with ...
Vincent M. Morin +4 more
doaj +1 more source
Preparation, Thermal Behavior, and Conformational Stability of HMX/Cyclopentanone Cocrystallization
The cocrystallization of 1,3,5,7-tetranitro-1,3,5,7-tetrazolidine (HMX) with cyclopentanone was achieved via a controlled cooling method, followed by comprehensive characterization that confirmed the α-configuration of HMX within the cocrystal.
Yuting Tao +6 more
doaj +1 more source
Rosuvastatin calcium is a promising lipid-lowering agent and the drug of choice in hyperlipidemia. Conventional solid oral delivery of rosuvastatin is limited by its poor solubility and ultimately poor bioavailability.
Deepak Kulkarni, Sanjay Pekamwar
doaj +1 more source
Recent advances in pharmaceutical cocrystals of theophylline
Currently, cocrystallization is a promising strategy for tailoring the physicochemical properties of active pharmaceutical ingredients. Theophylline, an alkaloid and the most primary metabolite of caffeine, is a readily available compound found in tea ...
Yanxiao Jia +7 more
doaj +1 more source
Unveiling Solvent-Mediated Mechanochemical Cocrystallization Pathways by <i>In Situ</i> CLASSIC NMR Spectroscopy. [PDF]
Gołkowska AM +7 more
europepmc +1 more source
Systematic Scale-Up of Mechanochemical Paracetamol-Oxalic Acid Cocrystal Synthesis across Multiple Milling Technologies. [PDF]
Schöbel JH, Gopinath D, Felderhoff M.
europepmc +1 more source
Phase Diagram-Enabled Curcumin Isolation and Purification by Utilizing Resorcinol as Cocrystal Former and Additive. [PDF]
Weng YR +4 more
europepmc +1 more source
An Antibacterial "Drug-Drug" Cocrystal of Trimethoprim with Sulfathiazole Achieving Synchronized Dual-Drug Release and Pharmacokinetics. [PDF]
Li WH +8 more
europepmc +1 more source
An Optimization Approach for the Production of High-Purity Vitamin C‑Nicotinamide Cocrystals by the Gas Antisolvent (GAS) Technique with CO<sub>2</sub> and Ethanol. [PDF]
Balbinot Filho CA +8 more
europepmc +1 more source

