Results 101 to 110 of about 6,443 (221)

Bayesian Optimization of Solvent‐Free Thermal Amidation via Reactive Extrusion

Chemistry – A European Journal, Volume 32, Issue 22, 9 June 2026.
Thermal amidation between a carboxylic acid and an amine was successfully conducted in an extruder in the absence of solvent, coupling agent, or catalyst, relying on an adapted Bayesian Optimization protocol. Active pharmaceutical ingredient moclobemide was synthesized on a larger scale, achieving excellent yield and low Process Mass Intensity (PMI ...
Matthieu Lavayssiere, Xavier Bantreil, Frédéric Lamaty   +2 more
wiley   +1 more source

Polymorph control of felodipine form II in an attempted cocrystallization

, 2009
The metastable form II of racentic felodipine was obtained in an attempted cocrystallization with isonicotinamide. Its low temperature crystal structure was characterized by a ID hydrogen-bonded chain consisting of four independent felodipine molecules.
Boström, Dan,, Velaga, Sitaram,, Lou, Benyong,, Velaga, Sitaram P., Lou, Benyong   +4 more
core   +1 more source

Synthesis, Crystal Structure, Hirshfeld Surface, RDG, ELF, LOL, DFT, and Molecular Docking Studies of a Binuclear Copper(II) Carboxylate Complex

ChemistryOpen, Volume 15, Issue 6, June 2026.
A binuclear copper(II) phenylacetate–metronidazole complex was successfully synthesized and structurally characterized. Hirshfeld surface analysis confirmed dominant H···H interactions governing crystal packing stability. DFT calculations demonstrated strong agreement with experimental geometry.
Abiodun Atoyebi Ajibola, Mehran Feizi‐Dehnayebi, Senem Akkoc, Lesław Sieroń, Waldemar Maniukiewicz   +4 more
wiley   +1 more source

Host–Guest Cocrystallization of Phenanthrene[2]arene Macrocycles Facilitating Structure Determination of Liquid Organic Molecules

Molecules
Single-crystal X-ray diffraction analysis has emerged as the most reliable method for determining the structures of organic molecules. However, numerous analytes, such as liquid organic molecules, pose challenges in crystallization, making their ...
Guangchuan Ou, Yanfeng Zhang, Qiong Wang, Yingzhi Tan, Qiang Zhou, Fei Zeng   +5 more
doaj   +1 more source

Large-Periodicity Two-Dimensional Crystals by Cocrystallization

, 2016
Patterning surfaces with features on the low end of the nanoscale can efficiently be accomplished with physisorbed monolayers. Here, cocrystallization is revealed as a powerful approach toward dramatically increasing the periodicity of surface features ...
Katherine E. Plass (1916962), Keary M. Engle (1961296), Katie A. Cychosz (2176638), Adam J. Matzger (1326309)   +3 more
core   +1 more source

DNA recognition, cleavage, and toxic metal ion interaction of an artificial zinc finger protein inside E. coli cells

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Zinc finger proteins are essential for the proper functioning of eukaryotic organisms, while their artificial variants can be used in cancer therapy or gene editing via their specific DNA recognition. Zn(II) binding is indispensable for the structural integrity of zinc fingers.
Bálint Hajdu, Annamária Tóth, Bettina Fazekas, Melinda Horvát, Kohsuke Kato, Atsushi Kawaguchi, Kyosuke Nagata, Attila Jancsó, Béla Gyurcsik   +8 more
wiley   +1 more source

Cocrystallization of GABA adducts [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 2011
N. Khosavithitkul, K. J. Haller
openaire   +1 more source

Intrinsically dominant conformational diversity in PDZ1 within the tandem PDZ1–PDZ2 of human syntenin‐1 underlied by crystal structures

Protein Science, Volume 35, Issue 6, June 2026.
Abstract The intrinsic dynamic asymmetry between homologous PDZ domains in multidomain scaffold proteins offers insight into how they achieve multivalent partner recognition. Through a systematic x‐ray crystallographic analysis of tandem PDZ1–PDZ2 domains in human syntenin‐1 (SDCBP/MDA‐9), we solved nine high‐resolution structures and uncovered ...
Natsuno Ando, Yuya Hanazono, Koya Sakuma, Nobutaka Numoto, Ryusei Hamajima, Takeshi Tenno, Atsunori Oshima, Nobutoshi Ito, Hidekazu Hiroaki   +8 more
wiley   +1 more source

Thermal and Rheological Properties of Fischer–Tropsch Wax/High‐Flow LLDPE Blends

Macromolecular Materials and Engineering
Waxes find use as processing aids in filled compounds and polyethylene‐based masterbatches. In such applications, the thermal and physical property changes they impart to the polymer matrix are important.
Thobile Mhlabeni, Shatish Ramjee, Jorge López, Ana‐María Díaz‐Díaz, Ramón Artiaga, Walter Focke   +5 more
doaj   +1 more source

A hydrogen-bonded channel structure formed by a complex of uracil and melamine

Beilstein Journal of Organic Chemistry, 2007
The structure of a 1:1 complex of uracil and melamine obtained by cocrystallization has been investigated. The structure involves hydrogen bonded layers with apertures stacked along the a and b directions giving rise to channels, unlike the complex of ...
Reji Thomas, G. U. Kulkarni
doaj   +1 more source