Results 121 to 130 of about 6,443 (221)
Recent advances in pharmaceutical cocrystals of theophylline
Natural Products and BioprospectingCurrently, cocrystallization is a promising strategy for tailoring the physicochemical properties of active pharmaceutical ingredients. Theophylline, an alkaloid and the most primary metabolite of caffeine, is a readily available compound found in tea ...
Yanxiao Jia +7 more
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Scientia PharmaceuticaRosuvastatin calcium is a promising lipid-lowering agent and the drug of choice in hyperlipidemia. Conventional solid oral delivery of rosuvastatin is limited by its poor solubility and ultimately poor bioavailability.
Deepak Kulkarni, Sanjay Pekamwar
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Extending the chiral resolution toolbox using cocrystallization
, 2023 Research on chirality and chiral resolution experienced a long history, while studies on cocrystals are in the ascendant. In the pharmaceutical field, cocrystallization is found to be versatile, not only being used to modify API’s physicochemical ...
Zhou, Fuli
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Combining Sodium Profen Salts with Carbohydrates through Ionic Cocrystallization
Crystal engineering techniques that incorporate active pharmaceutical ingredients with sweetening agents present an effective methodology for mitigating the unpleasant taste characteristics of pharmaceutical compounds.
Leng, Fucheng +10 more
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Cocrystallization, an effective tool to improve drug solubility and bioavailability
Teniendo en cuenta que una de las problemáticas que se presentan hoy en día en las industrias farmacéuticas es la baja biodisponibilidad de los fármacos debido a la baja solubilidad que presenta en el cuerpo humano, el presente documento pretende ...
Urrea Rojas, Anamaría
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Organic cocrystals: From high‐performance molecular materials to multi‐functional applications
AggregateAdvancements in organic electronics are propelling the development of new material systems, where organic materials stand out for their unique benefits, including tunability and cost‐effectiveness.
Yuqing Ding, Yan Zhao, Yunqi Liu
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Thermodynamic Stability Is a Poor Indicator of Cocrystallization in Models of Organic Molecules
Cocrystallizing a given molecule with another can be useful for adjusting the physical properties of molecules in the solid state. However, most combinations of molecules do not readily cocrystallize but form either one-component crystals or amorphous ...
Michael Gruenwald (17816419) +2 more
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Unveiling Solvent-Mediated Mechanochemical Cocrystallization Pathways by <i>In Situ</i> CLASSIC NMR Spectroscopy. [PDF]
Mol PharmGołkowska AM +7 more
europepmc +1 more source
Challenges in cocrystallization of chiral compounds : cocrystals of amino acids and profens
, 2017 Cocrystals are of interest to pharmaceutical industry as they allow varying pharmacological properties of drugs. Moreover, owing to some specific properties, cocrystals can be used in other crystallization applications, e.g., as a purification tool or ...
Tumanova, Natalia
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