Results 11 to 20 of about 10,442 (249)
Application of cosolvency and cocrystallization approach to enhance acyclovir solubility [PDF]
BMC ChemistryAcyclovir (ACY) is a commonly used antiviral drug with limited aqueous solubility and poor permeability. It is administered via oral and intravenous routes.
Elham Azad Khiabani +2 more
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Polymer TestingThe incorporation of HMX and CL-20 as component particles can greatly improve the energy efficiency of composite propellants. Nevertheless, the occurrence of cocrystallization arises when HMX and CL-20 exists together.
Jiangtao Wang +3 more
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Recent advances in pharmaceutical cocrystals of theophylline [PDF]
Natural Products and BioprospectingCurrently, cocrystallization is a promising strategy for tailoring the physicochemical properties of active pharmaceutical ingredients. Theophylline, an alkaloid and the most primary metabolite of caffeine, is a readily available compound found in tea ...
Yanxiao Jia +7 more
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Solution Cocrystallization: A Scalable Approach for Cocrystal Production
Crystals, 2021 With an increasing interest in cocrystals due to various advantages, demand for large-scale cocrystallization techniques is rising. Solution cocrystallization is a solvent-based approach that utilizes several single-component crystallization concepts as ...
Nitin Pawar +3 more
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Antibiotics, 2021 Cocrystallization is a promising approach to alter physicochemical properties of active pharmaceutical ingredients (hereafter abbreviated as APIs) bearing poor profile.
Noor Ul Islam +6 more
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Pharmaceutics, 2023 The chemotherapeutic agent known as 5-fluorouracil (5-FU) is an artificial fluoropyrimidine antimetabolite that has been widely used for its antineoplastic properties. Cocrystals of 5-fluorouracil (5-FU) with five different Schiff bases (benzylidene-urea
Farhat Jubeen +6 more
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Journal of Food Quality, 2022 Cocrystallization, vacuum drying, and plating are three potential applications to preserve the antioxidant activity of moringa leaves. Moringa leaves extract was incorporated with sucrose at the same concentration (7 : 100, solid : solid) for all ...
Bambang Nurhadi +4 more
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Urea as a Cocrystal Former—Study of 3 Urea Based Pharmaceutical Cocrystals
Pharmaceutics, 2021 Cocrystallization is commonly used for its ability to improve the physical properties of APIs, such as solubility, bioavailability, compressibility, etc.
Fucheng Leng, Koen Robeyns, Tom Leyssens
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Screening of coformers for quercetin cocrystals through mechanochemical methods
Eclética Química, 2022 Quercetin (QUE) is a nutraceutical compound that exhibits pharmacological properties such as antioxidant, cardioprotective, anti-ulcer, and anti-inflammatory effects.
Fayene Zeferino Ribeiro de Souza +4 more
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Competitive cocrystallization and its application in the separation of flavonoids
IUCrJ, 2021 Recently, cocrystallization has been widely employed to tailor physicochemical properties of drugs in the pharmaceutical field. In this study, cocrystallization was applied to separate natural compounds with similar structures.
Yanming Xia +5 more
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