Results 21 to 30 of about 10,442 (249)
Pharmaceutics, 2022 The mechanochemical synthesis of cocrystals has been introduced as a promising approach of formulating poorly water-soluble active pharmaceutical ingredients (APIs).
Maryam Karimi-Jafari +4 more
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Molecules, 2022 Melt-cast explosive 2,4-dinitroanisole (DNAN) crystal and its cocrystals DNAN/1,3-dinitrobenzene (DNB) and DNAN/2-nitroaniline (NA) were used to identify the effects of cocrystallization on the crystal structure, non-covalent interactions, and melting ...
Defu Wang, Lei Yang, Weihua Zhu
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Virtual Screening, Structural Analysis, and Formation Thermodynamics of Carbamazepine Cocrystals
Pharmaceutics, 2023 In this study, the existing set of carbamazepine (CBZ) cocrystals was extended through the successful combination of the drug with the positional isomers of acetamidobenzoic acid.
Artem O. Surov +5 more
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Recent Progress on Synthesis, Characterization, and Performance of Energetic Cocrystals: A Review
Molecules, 2022 In the niche area of energetic materials, a balance between energy and safety is extremely important. To address this “energy–safety contradiction”, energetic cocrystals have been introduced.
Manzoor Sultan +7 more
doaj +1 more source
Obtaining Cocrystals by Reaction Crystallization Method: Pharmaceutical Applications
Pharmaceutics, 2021 Cocrystals have gained attention in the pharmaceutical industry due to their ability to improve solubility, stability, in vitro dissolution rate, and bioavailability of poorly soluble drugs. Conceptually, cocrystals are multicomponent solids that contain
Isabela Fanelli Barreto Biscaia +3 more
doaj +1 more source
Matrix Assisted Cocrystallization as an example of continuous and scalable method of obtaining pharmaceutical cocrystals on an industrial scale [PDF]
Farmacja Polska, 2021 Cocrystals can be defined as crystalline solids composed of at least two compounds in a stoichiometric ratio which interact nonionically. While one of the components is an active pharmaceutical ingredient (API) the term ‘pharmaceutical cocrystal’ could ...
Anna Magdalena Gołkowska +3 more
doaj +1 more source
Synergetic Explosive Performance through Cocrystallization
Crystal Growth & Design, 2021 A 1:2 cocrystal of 4H,8H-difurazano[3,4-b:3′,4′-e]pyrazine and hydroxylamine has been prepared that displays 1,3,5-triamino-2,4,6-trinitrobenzene-like sensitivity and performance.
Christopher J. Snyder +3 more
openaire +2 more sources
Pharmaceutics, 2022 The application of a computational screening methodology based on the calculation of intermolecular interaction energies has guided the discovery of new multicomponent solid forms of the oral antiviral Adefovir Dipivoxyl.
Rafael Barbas +7 more
doaj +1 more source
The Active Site Sulfenic Acid Ligand in Nitrile Hydratases Can Function as a Nucleophile [PDF]
, 2014 Nitrile hydratase (NHase) catalyzes the hydration of nitriles to their corresponding commercially valuable amides at ambient temperatures and physiological pH.
Holz, Richard C. +4 more
core +3 more sources