Introduction : Paracetamol is an effective analgesic to relieve mild to moderate pain when it is used in therapeutic doses. Codeine is an opioid analgesic to relieve moderate to severe pain. Both are metabolized in the liver and have different mechanisms
Rona Ayu Hanifah +3 more
doaj +1 more source
Content of alkaloids in ornamental Papaver somniferum L. cultivars growing in Estonia; pp. 34–39 [PDF]
The alkaloid content in industrial opium poppies (Papaver somniferum L.) has been studied by numerous authors, but not in ornamental cultivars.The aim of the study was to investigate the content of morphine, codeine, and papaverine in P.
Andres Meos, Liis Saks, Ain Raal
doaj +1 more source
7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects [PDF]
Mitragynina speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction.
Ansonoff, Michael +12 more
core +3 more sources
Older patients' prescriptions screening in the community pharmacy: development of the Ghent Older People's Prescriptions community Pharmacy Screening (GheOP3S) tool [PDF]
Background: Ageing of the population often leads to polypharmacy. Consequently, potentially inappropriate prescribing (PIP) becomes more frequent. Systematic screening for PIP in older patients in primary care could yield a large improvement in health ...
Boussery, Koen +5 more
core +5 more sources
Illicit drug use and cerebral microbleeds in stroke and transient ischemic attack patients [PDF]
Background: Cerebral microbleeds (CMB) signal cerebral small vessel disease and are associated with ischemic stroke (IS) incidence, recurrence, and complications.
Abbas, Saleh +10 more
core +1 more source
Crystallization and preliminary diffraction studies of morphinone reductase, a flavoprotein involved in the degradation of morphine alkaloids [PDF]
Morphinone reductase from Pseudomonas putida M10, a flavoprotein involved in the degradation of morphine alkaloids, was purified from an overexpressing strain of Escherichia coli and crystallized using the hanging-drop vapour-diffusion method ...
Bruce, N C +4 more
core +1 more source
Background: Guidelines recommend against all codeine use in children for its common indications of analgesia and cough suppression because of uncertain benefits and potential risk of death.
Sachiko Ono +3 more
doaj +1 more source
Background Misuse and dependency of opioids especially codeine-containing products is of increasing global concern. Inappropriate use of opioids among healthcare students could affect quality of service and ethical conducts of these future professionals,
W. Akande-Sholabi +3 more
semanticscholar +1 more source
COMPARATIVE STUDY OF PAIN KILLER DRUGS EFFECTS AFTER THE DENTAL IMPLANT PLACEMENT IN THE ACTIVE ADULT POPULATION [PDF]
There is controversy in recent studies on the use of NSAIDs used to control pain and swelling after the insertion of dental implants that may interfere with the osteointegration process.
Ruxandra Nicolette Voinea Georgescu +5 more
doaj +1 more source
Representations of Codeine Misuse on Instagram: Content Analysis
Background Prescription opioid misuse has doubled over the past 10 years and is now a public health epidemic. Analysis of social media data may provide additional insights into opioid misuse to supplement the traditional approaches of data collection (eg,
R. Cherian +3 more
semanticscholar +1 more source

