Results 31 to 40 of about 95,678 (274)
In Arabidopsis thaliana codon volatility scores reflect GC3 composition rather than selective pressure [PDF]
, 2012 Background: Synonymous codon usage bias has typically been correlated with, and attributed to translational efficiency. However, there are other pressures on genomic sequence composition that can affect codon usage patterns such as mutational biases ...
Donoghue, MTA +6 more
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Quantifying Position-Dependent Codon Usage Bias [PDF]
Molecular Biology and Evolution, 2014 Although the mapping of codon to amino acid is conserved across nearly all species, the frequency at which synonymous codons are used varies both between organisms and between genes from the same organism. This variation affects diverse cellular processes including protein expression, regulation, and folding. Here, we mathematically model an additional
Hockenberry, Adam J. +3 more
openaire +2 more sources
Genetic Evolution and Molecular Selection of the HE Gene of Influenza C Virus [PDF]
, 2019 Influenza C virus (ICV) was first identified in humans and swine, but recently also in cattle, indicating a wider host range and potential threat to both the livestock industry and public health than was originally anticipated.
He, Wanting +10 more
core +1 more source
Codon bias and gene expression [PDF]
FEBS Letters, 1991 The frequencies with which individual synonymous codons are used to code their cognate amino acids is quite variable from genome to genome and within genomes, from gene to gene. One particularly well documented codon bias is that associated with highly expressed genes in bacteria as well as in yeast; this is the so‐called major codon bias.
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Ribo-seq enlightens codon usage bias [PDF]
DNA Research, 2017 Codon usage is biased between lowly and highly expressed genes in a genome-specific manner. This universal bias has been well assessed in some unicellular species, but remains problematic to assess in more complex species. We propose a new method to compute codon usage bias based on genome wide translational data. A new technique based on sequencing of
Paulet, Damien +2 more
openaire +3 more sources
Rapid divergence of codon usage patterns within the rice genome [PDF]
, 2007 Background Synonymous codon usage varies widely between genomes, and also between genes within genomes. Although there is now a large body of data on variations in codon usage, it is still not clear if the observed patterns reflect the effects of ...
Huai-Chun Wang, Donal A Hickey
core +2 more sources
Codon bias analyses on thyroid carcinoma genes [PDF]
Minerva Endocrinologica, 2021 Thyroid carcinoma is one of the most common cancers in the world. Although the genetics of thyroid carcinoma was intensively studied, new mechanisms could be involved in its development as the codon bias. In this paper, we studied the codon bias of thyroid-cancer genes, considering not only the sequences but also the synonymous mutations.Different ...
Pepe, Daniele, de Keersmaecker, Kim
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Analysis of synonymous codon usage patterns in mitochondrial genomes of nine Amanita species
Frontiers in Microbiology, 2023 IntroductionCodon basis is a common and complex natural phenomenon observed in many kinds of organisms.MethodsIn the present study, we analyzed the base bias of 12 mitochondrial core protein-coding genes (PCGs) shared by nine Amanita species.ResultsThe ...
Qiang Li +8 more
doaj +1 more source
Codon Usage Bias Correlates With Gene Length in Neurodegeneration Associated Genes
Frontiers in Neuroscience, 2022 Codon usage analysis is a crucial part of molecular characterization and is used to determine the factors affecting the evolution of a gene. The length of a gene is an important parameter that affects the characteristics of the gene, such as codon usage,
Rekha Khandia +9 more
doaj +1 more source
Site-Specific Codon Bias in Bacteria [PDF]
Genetics, 1996 Abstract Sequences of the gapA and ompA genes from 10 genera of enterobacteria have been analyzed. There is strong bias in codon usage, but different synonymous codons are preferred at different sites in the same gene. Site-specific preference for unfavored codons is not confined to the first 100 codons and is usually manifest between ...
J M, Smith, N H, Smith
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