Results 1 to 10 of about 231,600 (190)

Physiological metabolic analysis and process optimization of hypoxia in promoting coenzyme Q10 biosynthesis and accumulation in Rhodobacter sphaeroides HY01 [PDF]

open access: yesSynthetic and Systems Biotechnology
Coenzyme Q10 fermentation by Rhodobacter sphaeroides (R. sphaeroides) is highly aerobic. However, its biosynthesis and accumulation are paradoxically induced under hypoxic conditions.
Bo Li   +9 more
doaj   +2 more sources

Inhibition of Histone Lysine Acetyltransferases by Coenzyme A Analogs [PDF]

open access: yesMolecules
Histone lysine acetylation is a widespread posttranslational modification, essential for vital functions in eukaryotic organisms. Histone lysine acetyltransferases (KATs) employ acetyl-coenzyme A as a universal acetyl donor for acetylation of lysine ...
Faidra Voukia   +3 more
doaj   +2 more sources

Pantothenic acid – a scoping review for Nordic Nutrition Recommendations 2023

open access: yesFood & Nutrition Research, 2023
Pantothenic acid, also referred to as vitamin B5, is a water-soluble vitamin that has essential functions in the body as a component of coenzyme A (CoA) and acyl carrier protein (ACP).
Riitta Freese   +2 more
doaj   +1 more source

Iso-coenzyme A [PDF]

open access: yesJournal of Biological Chemistry, 2005
Iso-coenzyme A is an isomer of coenzyme A in which the monophosphate is attached to the 2'-carbon of the ribose ring. Although iso-CoA was first reported in 1959 (Moffatt, J. G., and Khorana, H. G. (1959) J. Am. Chem. Soc. 81, 1265-1265) to be a by-product of the chemical synthesis of CoA, relatively little attention has been focused on iso-CoA or on ...
Kristi L, Burns   +4 more
openaire   +2 more sources

A conserved oxalyl-coenzyme A decarboxylase in oxalate catabolism

open access: yesPlant Signaling & Behavior, 2022
The ability to biosynthesize oxalic acid can provide beneficial functions to plants; however, uncontrolled or prolonged exposure to this strong organic acid results in multiple physiological problems.
Ninghui Cheng   +4 more
doaj   +1 more source

TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase

open access: yeseLife, 2021
TMEM120A, also named as TACAN, is a novel membrane protein highly conserved in vertebrates and was recently proposed to be a mechanosensitive channel involved in sensing mechanical pain.
Jing Xue   +8 more
doaj   +1 more source

Evaluating the Genetic Capacity of Mycoplasmas for Coenzyme A Biosynthesis in a Search for New Anti-mycoplasma Targets

open access: yesFrontiers in Microbiology, 2021
Mycoplasmas are responsible for a wide range of disease states in both humans and animals, in which their parasitic lifestyle has allowed them to reduce their genome sizes and curtail their biosynthetic capabilities.
Tertius Alwyn Ras   +2 more
doaj   +1 more source

The pathophysiology of leg cramping during dialysis and the use of carnitine in its treatment

open access: yesPhysiological Reports, 2021
Leg cramping is a common side effect of hemodialysis, and this is frequently treated by the administration of carnitine, but this is not effective in every patient. Alkalosis is a key component of the etiology of leg cramping during hemodialysis sessions.
Akira Takahashi
doaj   +1 more source

FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR) [PDF]

open access: yes, 2014
Adenosylcobalamin, the coenzyme form of vitamin B12, is one Nature's most complex coenzyme whose de novo biogenesis proceeds along either an anaerobic or aerobic metabolic pathway. The aerobic synthesis involves reduction of the centrally chelated cobalt
Alan Scott   +45 more
core   +3 more sources

Oxalate-silica gel thin-layer system for free 2-hydroxy fatty acids and for fatty acyl coenzyme A

open access: yesJournal of Lipid Research, 1972
The 2-hydroxy fatty acids tend to yield streaks in thin-layer chromatography on silica gel plates. If potassium oxalate is included with binder-free silica gel, good spots are obtained.
M. David Ullman, Norman S. Radin
doaj   +1 more source

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