Results 11 to 20 of about 136,670 (296)

Auxotrophic Selection Strategy for Improved Production of Coenzyme B12 in Escherichia coli

open access: yesiScience, 2020
Summary: The production of coenzyme B12 using well-characterized microorganisms, such as Escherichia coli, has recently attracted considerable attention to meet growing demands of coenzyme B12 in various applications. In the present study, we designed an
Myung Hyun Noh   +4 more
doaj   +1 more source

Investigation of coenzyme Q10 status, serum amyloid-β, and tau protein in patients with dementia

open access: yesFrontiers in Aging Neuroscience, 2022
ObjectivesDementia is an oxidative stress-related disease. Coenzyme Q10 is a nutrient that occurs naturally in the human body and acts as an antioxidant.
Po-Sheng Chang   +10 more
doaj   +1 more source

Optimized self-microemulsifying drug delivery system improves the oral bioavailability and brain delivery of coenzyme Q10

open access: yesDrug Delivery, 2022
Our study aimed to develop a self-microemulsifying drug delivery system for the poorly aqueous-soluble drug Coenzyme Q10, to improve the dissolution and the oral bioavailability.
Thapa Chhitij   +11 more
doaj   +1 more source

Determination of Coenzyme A and Acetyl-Coenzyme A in Biological Samples Using HPLC with UV Detection

open access: yesMolecules, 2017
Coenzyme A (CoA) and acetyl-coenzyme A (acetyl-CoA) play essential roles in cell energy metabolism. Dysregulation of the biosynthesis and functioning of both compounds may contribute to various pathological conditions.
Yevgeniya I. Shurubor   +7 more
doaj   +1 more source

Urinary coenzyme Q10 as a diagnostic biomarker and predictor of remission in a patient with ADCK4-associated Glomerulopathy: a case report

open access: yesBMC Nephrology, 2021
Background AarF domain-containing kinase 4 (ADCK4)-associated glomerulopathy is a mitochondrial nephropathy caused by mutations in the ADCK4 gene, which disrupt coenzyme Q10 biosynthesis.
Yan Zhang   +8 more
doaj   +1 more source

Coenzyme a Biochemistry: From Neurodevelopment to Neurodegeneration

open access: yesBrain Sciences, 2021
Coenzyme A (CoA) is an essential cofactor in all living organisms. It is involved in a large number of biochemical processes functioning either as an activator of molecules with carbonyl groups or as a carrier of acyl moieties.
Luca Mignani   +3 more
doaj   +1 more source

Atherosclerosis and Coenzyme Q10 [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Atherosclerosis is the most common cause of cardiac deaths worldwide. Classically, atherosclerosis has been explained as a simple arterial lipid deposition with concomitant loss of vascular elasticity. Eventually, this condition can lead to consequent blood flow reduction through the affected vessel.
Juan M. Suárez-Rivero   +10 more
openaire   +4 more sources

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family

open access: yesJournal of Lipid Research, 2004
By consensus, the acyl-CoA synthetase (ACS) community, with the advice of the human and mouse genome nomenclature committees, has revised the nomenclature for the mammalian long-chain acyl-CoA synthetases.
Douglas G. Mashek   +19 more
doaj   +1 more source

Isolation of an Enzyme-Coenzyme A Intermediate from Succinyl Coenzyme A-Acetoacetate Coenzyme A Transferase [PDF]

open access: yesJournal of Biological Chemistry, 1967
Abstract An alkali-labile enzyme-coenzyme A intermediate has been isolated by molecular exclusion chromatography of succinyl-CoA-acetoacetate coenzyme A transferase after incubation with acetoacetyl-CoA or succinyl-CoA. Treatment of the intermediate with tritium-labeled sodium borohydride results in enzyme inactivation and incorporation of ...
William P. Jencks, Louis B. Hersh
openaire   +2 more sources

Characterization of Plasmodium falciparum Pantothenate Kinase and Identification of Its Inhibitors From Natural Products

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Coenzyme A (CoA) is a well-known cofactor that plays an essential role in many metabolic reactions in all organisms. In Plasmodium falciparum, the most deadly among Plasmodium species that cause malaria, CoA and its biosynthetic pathway have been proven ...
Arif Nurkanto   +15 more
doaj   +1 more source

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