Results 21 to 30 of about 248,704 (239)
Coenzyme a Biochemistry: From Neurodevelopment to Neurodegeneration
Brain Sciences, 2021 Coenzyme A (CoA) is an essential cofactor in all living organisms. It is involved in a large number of biochemical processes functioning either as an activator of molecules with carbonyl groups or as a carrier of acyl moieties.
Luca Mignani +3 more
doaj +1 more source
Atherosclerosis and Coenzyme Q10 [PDF]
International Journal of Molecular Sciences, 2019 Atherosclerosis is the most common cause of cardiac deaths worldwide. Classically, atherosclerosis has been explained as a simple arterial lipid deposition with concomitant loss of vascular elasticity. Eventually, this condition can lead to consequent blood flow reduction through the affected vessel.
Juan M. Suárez-Rivero +10 more
openaire +4 more sources
Insights into molecular mechanisms of disease in Neurodegeneration with Brain Iron Accumulation; unifying theories. [PDF]
, 2016 Neurodegeneration with brain iron accumulation (NBIA) is a group of disorders characterised by dystonia, parkinsonism and spasticity. Iron accumulates in the basal ganglia and may be accompanied by Lewy bodies, axonal swellings and hyperphosphorylated ...
Adibhatla +148 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Coenzyme A (CoA) is a well-known cofactor that plays an essential role in many metabolic reactions in all organisms. In Plasmodium falciparum, the most deadly among Plasmodium species that cause malaria, CoA and its biosynthetic pathway have been proven ...
Arif Nurkanto +15 more
doaj +1 more source
metaSHARK: software for automated metabolic network prediction from DNA sequence and its application to the genomes of Plasmodium falciparum and Eimeria tenella [PDF]
, 2005 The metabolic SearcH And Reconstruction Kit (metaSHARK) is a new fully automated software package for the detection of enzyme-encoding genes within unannotated genome data and their visualization in the context of the surrounding metabolic network ...
McConkey, G.A. +3 more
core +2 more sources
Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family
Journal of Lipid Research, 2004 By consensus, the acyl-CoA synthetase (ACS) community, with the advice of the human and mouse genome nomenclature committees, has revised the nomenclature for the mammalian long-chain acyl-CoA synthetases.
Douglas G. Mashek +19 more
doaj +1 more source
Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]
, 2017 Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio +6 more
core +1 more source
Isolation of an Enzyme-Coenzyme A Intermediate from Succinyl Coenzyme A-Acetoacetate Coenzyme A Transferase [PDF]
Journal of Biological Chemistry, 1967 Abstract An alkali-labile enzyme-coenzyme A intermediate has been isolated by molecular exclusion chromatography of succinyl-CoA-acetoacetate coenzyme A transferase after incubation with acetoacetyl-CoA or succinyl-CoA. Treatment of the intermediate with tritium-labeled sodium borohydride results in enzyme inactivation and incorporation of ...
William P. Jencks, Louis B. Hersh
openaire +2 more sources
A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases
Journal of Lipid Research, 2005 Acyl-CoA thioesterases, also known as acyl-CoA hydrolases, are a group of enzymes that hydrolyze CoA esters such as acyl-CoAs (saturated, unsaturated, branched-chain), bile acid-CoAs, CoA esters of prostaglandins, etc., to the corresponding free acid and
Mary C. Hunt +5 more
doaj +1 more source
Remnants of an ancient metabolism without phosphate [PDF]
, 2017 Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E. +3 more
core +1 more source