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Coenzyme Q10 (CoQ10) is among the most widely used dietary and nutritional supplements on the market. CoQ10 has several fundamental properties that may be beneficial in several clinical situations. This article reviews the pertinent chemical, metabolic, and physiologic properties of CoQ10 and the scientific data and clinical trials that address its use
Joseph Katzinger +2 more
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Investigation of coenzyme Q10 status, serum amyloid-β, and tau protein in patients with dementia
ObjectivesDementia is an oxidative stress-related disease. Coenzyme Q10 is a nutrient that occurs naturally in the human body and acts as an antioxidant.
Po-Sheng Chang +10 more
doaj +1 more source
Our study aimed to develop a self-microemulsifying drug delivery system for the poorly aqueous-soluble drug Coenzyme Q10, to improve the dissolution and the oral bioavailability.
Thapa Chhitij +11 more
doaj +1 more source
Background AarF domain-containing kinase 4 (ADCK4)-associated glomerulopathy is a mitochondrial nephropathy caused by mutations in the ADCK4 gene, which disrupt coenzyme Q10 biosynthesis.
Yan Zhang +8 more
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Evaluating the Role of Coenzyme Q10 in Migraine Therapy-A Narrative Review. [PDF]
Fajkiel-Madajczyk A +4 more
europepmc +3 more sources
Analysis and Suggestions of Evaluation and Approval for Health Foods Containing Coenzyme Q10
Coenzyme Q10 is a fat-soluble vitamin-like benzoquinone compound, which is synthesized endogenously from tyrosine in human body. It has many physiological functions, such as participating in ATP production capacity, scavenging free radicals and anti ...
Yu JIANG +4 more
doaj +1 more source
Effect of iron and silver nanoparticles on coenzyme Q10 production by Gluconobacter japonicus FM10
Background and Objectives: Coenzyme Q10 is an anti-aging agent whose demand is increasing progressively. There are various strategies used for increasing coenzyme Q10 production by microorganisms.
Foozieh Moghadami, Ramin Hosseini
doaj +1 more source
Heart Failure—Do We Need New Drugs or Have Them Already? A Case of Coenzyme Q10
Heart failure (HF) is a global epidemic that contributes to the deterioration of quality of life and its shortening in 1–3% of adult people in the world. Pharmacotherapy of HF should rely on highly effective drugs that improve prognosis and prolong life.
Krzysztof J. Filipiak +3 more
doaj +1 more source
Osteoarthritis (OA) causes oxidative stress. Coenzyme Q10 is an antioxidant that participates in energy production in the human body. The purpose of this study was to investigate the relationships among coenzyme Q10 status, oxidative stress, antioxidant ...
Po-Sheng Chang +4 more
doaj +1 more source
Effect of Black Sesame Oil Lecithin Solution on Bone Metabolism in Naturally Growing Aged Mice
To observe the effect of black sesame oil lecithin solution on bone metabolism in naturally grown aging mice and compare with vitamin E.8-month-old SPF Kunming mice were randomly divided into normal saline group (NS group),vitamin E group (VE group ...
LV Si-min +5 more
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