Results 1 to 10 of about 81,810 (279)
Investigation of coenzyme Q10 status, serum amyloid-β, and tau protein in patients with dementia
Frontiers in Aging Neuroscience, 2022 ObjectivesDementia is an oxidative stress-related disease. Coenzyme Q10 is a nutrient that occurs naturally in the human body and acts as an antioxidant.
Po-Sheng Chang +10 more
doaj +2 more sources
Early Coenzyme Q10 Supplementation in Primary Coenzyme Q10 Deficiency [PDF]
New England Journal of Medicine, 2008 To the Editor: Primary coenzyme Q10 deficiency is considered to be the only treatable mitochondrial disorder, since patients have a response to oral coenzyme Q10 supplementation. The disease usually manifests with nephropathy and encephalomyopathy.1 It has been shown that oral coenzyme Q10 may stop the progression of encephalopathy, but no benefit from
Giovanni Montini +2 more
openalex +5 more sources
Metabolic Targets of Coenzyme Q10 in Mitochondria [PDF]
Antioxidants, 2021 Coenzyme Q10 (CoQ10) is classically viewed as an important endogenous antioxidant and key component of the mitochondrial respiratory chain. For this second function, CoQ molecules seem to be dynamically segmented in a pool attached and engulfed by the ...
A. Hidalgo-Gutiérrez +6 more
semanticscholar +8 more sources
Nutrition Journal, 2022 Background Metabolic syndrome (MetS) as a cluster of conditions including hyperlipidemia, hypertension, hyperglycemia, insulin resistance, and abdominal obesity is linked to cardiovascular diseases and type 2 diabetes.
Abbas Ali Sangouni +4 more
doaj +2 more sources
Antioxidants, 2022 The aim of this study was to explore the use of coenzyme Q10 and skeletal muscle protein biomarkers in the diagnosis of sarcopenia. Subjects with or without sarcopenia were recruited.
Chi-Hua Yen +3 more
doaj +2 more sources
Coenzyme Q10 and Neurological Diseases [PDF]
Pharmaceuticals, 2009 Coenzyme Q10 (CoQ10, or ubiquinone) is a small electron carrier of the mitochondrial respiratory chain with antioxidant properties. CoQ10 supplementation has been widely used for mitochondrial disorders. The rationale for using CoQ10 is very powerful when this compound is primary decreased because of defective synthesis.
Michelangelo Mancuso +4 more
openalex +5 more sources
Biological Variation of Coenzyme Q10 [PDF]
Clinical Chemistry, 2005 Coenzyme Q10 (CoQ10) is an essential cofactor in the mitochondrial electron transport chain and is found in all cell membranes. It is present in the body in both the reduced and oxidized forms, with the reduced form (CoQ10H2) having antioxidant properties.
Sarah L. Molyneux +3 more
openalex +5 more sources
Antioxidants, 2020 Osteoarthritis (OA) causes oxidative stress. Coenzyme Q10 is an antioxidant that participates in energy production in the human body. The purpose of this study was to investigate the relationships among coenzyme Q10 status, oxidative stress, antioxidant ...
Po-Sheng Chang +4 more
doaj +2 more sources
Coenzyme Q10 and Obesity: An Overview. [PDF]
Antioxidants (Basel)There is evidence for the involvement of mitochondrial dysfunction, oxidative stress, ferroptosis, and inflammation in the pathogenesis of obesity. This, in turn, indicates a novel potential therapeutic role for supplemental coenzyme Q10 (CoQ10) in the management of obesity, due to the role of CoQ10 in promoting normal mitochondrial function, as an ...
Mantle D, Kozhevnikova S, Larsen S.
europepmc +3 more sources
The Relationship between Coenzyme Q10, Oxidative Stress, and Antioxidant Enzymes Activities and Coronary Artery Disease [PDF]
The Scientific World Journal, 2012 A higher oxidative stress may contribute to the pathogenesis of coronary artery disease (CAD). The purpose of this study was to investigate the relationship between coenzyme Q10 concentration and lipid peroxidation, antioxidant enzymes activities and the
Bor-Jen Lee +5 more
doaj +2 more sources