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The Relationship between Coenzyme Q10, Oxidative Stress, and Antioxidant Enzymes Activities and Coronary Artery Disease [PDF]
The Scientific World Journal, 2012 A higher oxidative stress may contribute to the pathogenesis of coronary artery disease (CAD). The purpose of this study was to investigate the relationship between coenzyme Q10 concentration and lipid peroxidation, antioxidant enzymes activities and the
Bor-Jen Lee +5 more
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Nutrition Journal, 2022 Background Metabolic syndrome (MetS) as a cluster of conditions including hyperlipidemia, hypertension, hyperglycemia, insulin resistance, and abdominal obesity is linked to cardiovascular diseases and type 2 diabetes.
Abbas Ali Sangouni +4 more
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Metabolic Targets of Coenzyme Q10 in Mitochondria [PDF]
Antioxidants, 2021 Coenzyme Q10 (CoQ10) is classically viewed as an important endogenous antioxidant and key component of the mitochondrial respiratory chain. For this second function, CoQ molecules seem to be dynamically segmented in a pool attached and engulfed by the ...
A. Hidalgo-Gutiérrez +6 more
semanticscholar +7 more sources
Early Coenzyme Q10 Supplementation in Primary Coenzyme Q10 Deficiency [PDF]
New England Journal of Medicine, 2008 To the Editor: Primary coenzyme Q10 deficiency is considered to be the only treatable mitochondrial disorder, since patients have a response to oral coenzyme Q10 supplementation. The disease usually manifests with nephropathy and encephalomyopathy.1 It has been shown that oral coenzyme Q10 may stop the progression of encephalopathy, but no benefit from
Giovanni Montini +2 more
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Coenzyme Q10 and Neurological Diseases [PDF]
Pharmaceuticals, 2009 Coenzyme Q10 (CoQ10, or ubiquinone) is a small electron carrier of the mitochondrial respiratory chain with antioxidant properties. CoQ10 supplementation has been widely used for mitochondrial disorders. The rationale for using CoQ10 is very powerful when this compound is primary decreased because of defective synthesis.
Michelangelo Mancuso +4 more
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Effects of Oral, Vaginal, and Transdermal Hormonal Contraception on Serum Levels of Coenzyme Q10, Vitamin E, and Total Antioxidant Activity [PDF]
Obstetrics and Gynecology International, 2010 The use of the transdermal contraceptive patch is associated with greater bioavailability of ethinyl estradiol (EE) compared with contraceptive vaginal ring or oral contraceptives (OC).
Prabhudas R. Palan +4 more
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Antioxidants, 2020 Osteoarthritis (OA) causes oxidative stress. Coenzyme Q10 is an antioxidant that participates in energy production in the human body. The purpose of this study was to investigate the relationships among coenzyme Q10 status, oxidative stress, antioxidant ...
Po-Sheng Chang +4 more
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Biological Variation of Coenzyme Q10 [PDF]
Clinical Chemistry, 2005 Coenzyme Q10 (CoQ10) is an essential cofactor in the mitochondrial electron transport chain and is found in all cell membranes. It is present in the body in both the reduced and oxidized forms, with the reduced form (CoQ10H2) having antioxidant properties.
Sarah L. Molyneux +3 more
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Development, characterization in vitro and in silico of coenzyme Q10 loaded myristic acid with different liquid lipids nanostructured lipid carriers [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2021 Context: Nanostructured lipid carriers can enhance skin penetration of active substances. Coenzyme Q10 is a lipophilic antioxidant, that has poor skin penetration. This limitation is overcome by nanostructured lipid carriers.
Ni Luh Dewi Aryani +4 more
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The Paradox of Coenzyme Q10 in Aging [PDF]
Nutrients, 2019 Coenzyme Q (CoQ) is an essential endogenously synthesized molecule that links different metabolic pathways to mitochondrial energy production thanks to its location in the mitochondrial inner membrane and its redox capacity, which also provide it with ...
M. E. Díaz-Casado +8 more
semanticscholar +5 more sources