Results 1 to 10 of about 36,139 (254)
The Relationship between Coenzyme Q10, Oxidative Stress, and Antioxidant Enzymes Activities and Coronary Artery Disease [PDF]
The Scientific World Journal, 2012 A higher oxidative stress may contribute to the pathogenesis of coronary artery disease (CAD). The purpose of this study was to investigate the relationship between coenzyme Q10 concentration and lipid peroxidation, antioxidant enzymes activities and the
Bor-Jen Lee +5 more
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Early Coenzyme Q10 Supplementation in Primary Coenzyme Q10 Deficiency [PDF]
New England Journal of Medicine, 2008 To the Editor: Primary coenzyme Q10 deficiency is considered to be the only treatable mitochondrial disorder, since patients have a response to oral coenzyme Q10 supplementation. The disease usually manifests with nephropathy and encephalomyopathy.1 It has been shown that oral coenzyme Q10 may stop the progression of encephalopathy, but no benefit from
Giovanni Montini +2 more
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Coenzyme Q10 and Neurological Diseases [PDF]
Pharmaceuticals, 2009 Coenzyme Q10 (CoQ10, or ubiquinone) is a small electron carrier of the mitochondrial respiratory chain with antioxidant properties. CoQ10 supplementation has been widely used for mitochondrial disorders. The rationale for using CoQ10 is very powerful when this compound is primary decreased because of defective synthesis.
Michelangelo Mancuso +4 more
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Coenzyme Q10 and Obesity: An Overview. [PDF]
Antioxidants (Basel)There is evidence for the involvement of mitochondrial dysfunction, oxidative stress, ferroptosis, and inflammation in the pathogenesis of obesity. This, in turn, indicates a novel potential therapeutic role for supplemental coenzyme Q10 (CoQ10) in the management of obesity, due to the role of CoQ10 in promoting normal mitochondrial function, as an ...
Mantle D, Kozhevnikova S, Larsen S.
europepmc +4 more sources
Biological Variation of Coenzyme Q10 [PDF]
Clinical Chemistry, 2005 Coenzyme Q10 (CoQ10) is an essential cofactor in the mitochondrial electron transport chain and is found in all cell membranes. It is present in the body in both the reduced and oxidized forms, with the reduced form (CoQ10H2) having antioxidant properties.
Sarah L. Molyneux +3 more
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Investigation of coenzyme Q10 status, serum amyloid-β, and tau protein in patients with dementia
Frontiers in Aging Neuroscience, 2022 ObjectivesDementia is an oxidative stress-related disease. Coenzyme Q10 is a nutrient that occurs naturally in the human body and acts as an antioxidant.
Po-Sheng Chang +10 more
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Drug Delivery, 2022 Our study aimed to develop a self-microemulsifying drug delivery system for the poorly aqueous-soluble drug Coenzyme Q10, to improve the dissolution and the oral bioavailability.
Thapa Chhitij +11 more
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BMC Nephrology, 2021 Background AarF domain-containing kinase 4 (ADCK4)-associated glomerulopathy is a mitochondrial nephropathy caused by mutations in the ADCK4 gene, which disrupt coenzyme Q10 biosynthesis.
Yan Zhang +8 more
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Atherosclerosis and Coenzyme Q10 [PDF]
International Journal of Molecular Sciences, 2019 Atherosclerosis is the most common cause of cardiac deaths worldwide. Classically, atherosclerosis has been explained as a simple arterial lipid deposition with concomitant loss of vascular elasticity. Eventually, this condition can lead to consequent blood flow reduction through the affected vessel.
Juan M. Suárez-Rivero +10 more
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Analysis and Suggestions of Evaluation and Approval for Health Foods Containing Coenzyme Q10
Shipin gongye ke-ji, 2022 Coenzyme Q10 is a fat-soluble vitamin-like benzoquinone compound, which is synthesized endogenously from tyrosine in human body. It has many physiological functions, such as participating in ATP production capacity, scavenging free radicals and anti ...
Yu JIANG +4 more
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