The Paradox of Coenzyme Q10 in Aging [PDF]
Coenzyme Q (CoQ) is an essential endogenously synthesized molecule that links different metabolic pathways to mitochondrial energy production thanks to its location in the mitochondrial inner membrane and its redox capacity, which also provide it with the capability to work as an antioxidant.
M Elena Díaz-Casado+8 more
openaire +4 more sources
Coenzyme Q10 as a therapeutic candidate for treating inherited photoreceptor degeneration [PDF]
Inherited photoreceptor degeneration (IPD): The human retina is a highly specialised tissue that enables the perception of light across a range of intensities and colours.
Biswas, Lincoln+5 more
core +4 more sources
Synthesis of Coenzyme Q10 [PDF]
Problem statement: CoQ10 is a key compound in ATP synthesis having wide number of health application especially for treating humans suffering from pathophysiological condition. The CoQ10 presently available in the market is solely derived from fermentation process. A commercially viable synthetic process is yet to be realized.
Machi Raju Garaga+4 more
openaire +2 more sources
A randomized, double-blind trial on the bioavailability of two CoQ10 formulations
The bioavailability of a single, 100 mg, dose of reduced Coenzyme Q10 (CoQH-CF) and Coenzyme Q10 formulation was compared in individuals of >60 years. Significantly higher (P
Malkanthi Evans+3 more
doaj
Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]
Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V+7 more
core +2 more sources
An Evaluation of the Protective Effects of Coenzyme Q10 on Fertility Parameters of Male Mice Treated with Methotrexate [PDF]
Background and Objective: Methotrexate (MTX) is a chemotherapy drug that has destructive effects on body tissues, including the male reproductive system.
M Babaei+4 more
doaj
Coenzyme Q10 Protect Mice Against Inflammatory Responses During Experimental Cerebral Malaria [PDF]
Malaria is a life threatening infectious diseases transmitted by the bite of infected female Anopheles mosquito and responsible for high morbidity and mortality rates.
Hoerauf, Achim+5 more
core +1 more source
Ethosomes for Coenzyme Q10 Cutaneous Administration: From Design to 3D Skin Tissue Evaluation
Ethosome represents a smart transdermal vehicle suitable for solubilization and cutaneous application of drugs. Coenzyme Q10 is an endogenous antioxidant whose supplementation can counteract many cutaneous disorders and pathologies.
Maddalena Sguizzato+9 more
semanticscholar +1 more source
Scale Up Nanostructured Lipid Carrier (NLC) Koenzim Q10 Menggunakan Matriks Lipid Asam Stearat-Isopropil Palmitat [PDF]
Overexposure to the sun can lead to the production of reactive oxygen species (ROS), which accelerates the aging process of the skin. The formation of ROS can be prevented with antioxidant compounds.
Aryani, Ni Luh Dewi, Juanita, Gracia
core +1 more source
Topical Delivery of Coenzyme Q10-Loaded Microemulsion for Skin Regeneration
The aim of this study was to develop a coenzyme Q10 (CoQ10) microemulsion system with improved solubility, penetration, and wound healing efficacy. Based on the pseudo-ternary diagram, microemulsions containing isopropyl myristate (IPM), Cremophor EL ...
Kyeong-A Ryu+5 more
semanticscholar +1 more source