Coenzyme Q10 Prevents Insulin Signaling Dysregulation and Inflammation Prior to Development of Insulin Resistance in Male Offspring of a Rat Model of Poor Maternal Nutrition and Accelerated Postnatal Growth. [PDF]
Low birth weight and rapid postnatal growth increases the risk of developing insulin resistance and type 2 diabetes in later life. However, underlying mechanisms and potential intervention strategies are poorly defined.
Carpenter, Asha +7 more
core +2 more sources
Abstract Background In infertile couples whose male partner has alterations in semen parameters frequently, a comprehensive andrological approach is lacking and approximately 30–50% are classified as idiopathic infertility. These couples are often directly addressed to assisted reproduction techniques (ARTs).
Giuseppe Grande +13 more
wiley +1 more source
Examining Effects of Metformin and Coenzyme Q10 on Doxorubicin-Induced Oxidative Hepatotoxicity in Rats [PDF]
Background and purpose: Cancer is considered one of the most common causes of mortality, in today’s world. A growing body of evidence has demonstrated that the global cancer burden is expected to rise significantly in the years to come.
Mohammad Bahrami +8 more
doaj
Autoimmune diseases are a heterogeneous group of afflictions whose etiopathogenesis is still incompletely understood. There is a great need to search for new treatment methods because of the difficulty of treatment, the numerous side effects of ...
Martyna Bukała +9 more
doaj +1 more source
The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome
The purpose of this study was to investigate the levels of coenzyme Q10 and vitamin E and the antioxidant status in subjects with metabolic syndrome (MS). Subjects with MS (n=72) were included according to the criteria for MS.
Chi-Hua Yen +5 more
doaj +1 more source
Atorvastatin therapy and antioxidant status correction in patients with metabolic syndrome
Aim. To study the changes in antioxidant status and glucose-insulin homeostasis among atorvastatin-treated patients with metabolic syndrome and to investigate the potential of coenzyme Q10 for the correction of these changes. Material and methods.
N. S. Yubitskaya +2 more
doaj +1 more source
Mitochondrial dysfunction promoted by Porphyromonas gingivalis lipopolysaccharide as a possible link between cardiovascular disease and periodontitis [PDF]
Oxidative stress is one of the factors that could explain the pathophysiological mechanism of inflammatory conditions that occur in cardiovascular disease (CVD) and periodontitis.
Battino, Maurizio +5 more
core
Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth. [PDF]
BACKGROUND: It is well established that low birth weight and accelerated postnatal growth increase the risk of liver dysfunction in later life. However, molecular mechanisms underlying such developmental programming are not well characterized, and ...
Aiken +48 more
core +3 more sources
Diagnosis and treatment of occipital brain lesions in children
Occipital brain lesions in children represent a diagnostic challenge due to the large spectrum of etiologies and overlapping clinical features. This review analyses common and less common causes of occipital brain lesions in children, including malformative, vascular, genetic/metabolic, infectious, inflammatory, and neoplastic conditions.
Luca Bartolini +4 more
wiley +1 more source
STATINS AND MYOPATHY: MOLECULAR MECHANISMS
The safety of statin therapy is considered. In particular the reasons of a complication such as myopathy are discussed in detail. The molecular mechanisms of statin myopathy , as well as its risk factors are presented.
O. M. Drapkina +2 more
doaj +3 more sources

