ATO enhanced the efficacy of PD‐1 inhibitors in HCC by inducing ICD via the ROS/ERS pathway. ABSTRACT Background Hepatocellular carcinoma (HCC) remains a major global health challenge, with limited efficacy of current immunotherapeutic strategies. Immunogenic cell death (ICD), characterized by the release of damage‐associated molecular patterns (DAMPs),
Xionghui Wang+5 more
wiley +1 more source
Antioxidantes dietéticos para la prevención de la periodontitis crónica y su tratamiento. Una revisión de las evidencias actuales procedentes de estudios en animales y humanos [PDF]
Objetivos. Dada la relación existente entre periodontitis crónica y altos niveles de estrés oxidativo, esta revisión pretende clarificar qué papel puede desempeñar la ingesta de los diferentes antioxidantes de la dieta en el mantenimiento de un ...
Bullon, Pedro
core
Cosupplementation with vitamin E and coenzyme Q10 reduces circulating markers of inflammation in baboons [PDF]
Xing Li Wang+3 more
openalex +1 more source
ABSTRACT Background In our previous study (NEXTAC‐ONE), the Nutrition and Exercise Treatment for Advanced Cancer (NEXTAC) program (including home‐based exercise and branched‐chain amino acid‐containing supplements combined with nutritional counselling) was shown to potentially prevent low muscle mass‐related disability in elderly cancer patients.
Shuichi Mitsunaga+21 more
wiley +1 more source
Mitochondrial Transplantation: A Novel Therapeutic Approach for Treating Diseases
This article describes the roles of mitochondria in health and disease and reviews the effects of mitochondrial transplantation in disease, including restoring ATP production, attenuating oxidative stress, modulating inflammatory responses, reducing apoptosis, promoting cell repair, and exhibiting antitumor properties.
Xinglu Miao+4 more
wiley +1 more source
NANOSTRUCTURED LIPID CARRIERS (NLCS): A PROMINENT TOPICAL DELIVERY SYSTEM FOR COENZYME Q10 AND MYRICA ESCULENTA LEAVES EXTRACT FOR ANTI-AGING POTENTIAL [PDF]
Objective: In this study, Myrica esculenta (ME) leaves extract along with Coenzyme Q10 was entrapped in nanostructured lipid carriers (NLCs). The formulation variables were successfully optimized using 23 factorial design.Methods: Preparation of NLC was ...
Kumar, Prashant, Singh, Anita
core +1 more source
Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats [PDF]
Paulo J. Oliveira+8 more
openalex +1 more source
Oxidative Stress in Antigen Processing and Presentation
Reactive oxygen species (ROS) play a crucial role in antigen processing and presentation, essential for linking innate and adaptive immunity. While balanced ROS levels promote immune function, excess ROS can disrupt antigen recognition, resulting in immune dysfunction.
Qinxia Chang+9 more
wiley +1 more source
Effect of coenzyme Q10 intake on endogenous coenzyme Q content, mitochondrial electron transport chain, antioxidative defenses, and life span of mice [PDF]
Rajindar S. Sohal+6 more
openalex +1 more source