Results 21 to 30 of about 36,753 (250)
Deutsches Ärzteblatt international, 2016 The prevalence of dyslipidemia is high. It is usually treated with statins which inhibit HMG-CoA reductase and also coenzyme Q10 synthesis. This may lead to muscle pain. The question whether coenzyme Q10 replacement treatment helps to improve these muscle symptoms has been evaluated in a prospective study.
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THE IMPACT OF CARDIOVASCULAR AND BRONCHOPULMONARY DISEASES ON COENZYME Q10 PLASMA CONCENTRATION
Сеченовский вестник, 2019 Introduction. Coenzyme Q10 plays an important role in the human body. Its main function is not only the transfer of electrons in the mitochondrial respiratory chain for the ATP synthesis, but it is also one of the most powerful antioxidants in the body ...
V. I. Zozina +4 more
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Development, characterization in vitro and in silico of coenzyme Q10 loaded myristic acid with different liquid lipids nanostructured lipid carriers [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2021 Context: Nanostructured lipid carriers can enhance skin penetration of active substances. Coenzyme Q10 is a lipophilic antioxidant, that has poor skin penetration. This limitation is overcome by nanostructured lipid carriers.
Ni Luh Dewi Aryani +4 more
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Coenzyme Q10 and Obesity: An Overview. [PDF]
Antioxidants (Basel)There is evidence for the involvement of mitochondrial dysfunction, oxidative stress, ferroptosis, and inflammation in the pathogenesis of obesity. This, in turn, indicates a novel potential therapeutic role for supplemental coenzyme Q10 (CoQ10) in the management of obesity, due to the role of CoQ10 in promoting normal mitochondrial function, as an ...
Mantle D, Kozhevnikova S, Larsen S.
europepmc +4 more sources
Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]
, 2017 Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio +6 more
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Journal of Nutritional Science and Vitaminology, 2005 Mutagenicity of organically synthesized coenzyme Q10 (CoQ10) was determined by Ames assay in the presence and absence of S9 mix. The tester strains were Salmonella typhimurium TA98, TA100, TA1535, and TA1537, and Escherichia coli WP2 uvr A. CoQ10 displayed no mutagenicity in any tester strain at any dose tested. Therefore, organically synthesized CoQ10
Kazutaka, Ikeda +2 more
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Early Coenzyme Q10 Supplementation in Primary Coenzyme Q10 Deficiency
New England Journal of Medicine, 2008 To the Editor: Primary coenzyme Q10 deficiency is considered to be the only treatable mitochondrial disorder, since patients have a response to oral coenzyme Q10 supplementation. The disease usually manifests with nephropathy and encephalomyopathy.1 It has been shown that oral coenzyme Q10 may stop the progression of encephalopathy, but no benefit from
MONTINI G +2 more
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Neurobiology of Disease, 2005 Neuronal cells depend on mitochondrial oxidative phosphorylation for most of their energy needs and therefore are at a particular risk for oxidative stress.
M. Somayajulu +5 more
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Ожирение и метаболизм, 2022 BACKGROUND: According to the involvement of oxidative stress in the pathogenesis of obesity, the plasma level of coenzyme q10 in the correlation relationship with lipid metabolism disorders and functional liver state is of interest to study.AIM ...
O. V. Povarova +6 more
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Anti-oxidants in Parkinson's disease therapy: a critical point of view [PDF]
, 2016 Parkinson's disease (PD) is a degenerative neurological syndrome, which is characterized by the preferential death of dopaminergic (DAergic) neurons in the SubstantiaNigra.
Beltramini, Mariano +3 more
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