Results 41 to 50 of about 37,360 (248)

Identification of Coenzyme Q10 and Skeletal Muscle Protein Biomarkers as Potential Factors to Assist in the Diagnosis of Sarcopenia

Antioxidants, 2022
The aim of this study was to explore the use of coenzyme Q10 and skeletal muscle protein biomarkers in the diagnosis of sarcopenia. Subjects with or without sarcopenia were recruited.
Chi-Hua Yen, Po-Sheng Chang, Yu-Hsun Chang, Ping-Ting Lin   +3 more
doaj   +1 more source

Ubiquinol Reduces Muscle Wasting but Not Fatigue in Tumor-Bearing Mice [PDF]

, 2014
Purpose: Fatigue is the most common and distressing symptom reported by cancer patients during and after treatment. Tumor growth increases oxidative stress and cytokine production, which causes skeletal muscle wasting and cardiac dysfunction. The purpose
Clark, Yvonne, McCarthy, Donna O., Szalacha, Laura A., Wold, Loren E.   +3 more
core   +2 more sources

Facing challenges in an ageing world [PDF]

, 2015
Editorial.The sponsorship of the following contributors made possible the meeting: Universidad Pablo de Olavide, Centro Andaluz de Biología del Desarrollo, Springer Publishers, International Coenzyme Q10 Association, Sociedad Española de Biología Celular,
López-Lluch, Guillermo, Rattan, Suresh I. S.   +1 more
core   +1 more source

Effects of Coenzyme Q10 on LDL Oxidation In vitro

Acta Medica Iranica, 2013
Coenzyme Q10, a lipid soluble benzoquinone, has excellent antioxidant and membrane stabilizing properties in the cardiac tissue. The present study investigated the effects of coenzyme Q10 on in vitro LDL oxidation quantitavely.
Hiroshi Mabuchi, Junji Kobayahi, Masa-aki Kawashiri, Hassan Ahmadvand   +3 more
doaj   +2 more sources

Effects of curcumin and/or coenzyme Q10 supplementation on metabolic control in subjects with metabolic syndrome: a randomized clinical trial

Nutrition Journal, 2022
Background Metabolic syndrome (MetS) as a cluster of conditions including hyperlipidemia, hypertension, hyperglycemia, insulin resistance, and abdominal obesity is linked to cardiovascular diseases and type 2 diabetes.
Abbas Ali Sangouni, Maryam Taghdir, Javad Mirahmadi, Mojtaba Sepandi, Karim Parastouei   +4 more
doaj   +1 more source

Neuroprotective Effect of Coenzyme Q10 in Hippocampal Injury in Balb/c Mouse [PDF]

, 2014
Coenzyme Q10 is a promising agent for neuroprotection in neurodegenerative diseases. Neuroprotective effects of Coenzyme Q10 demonstrated in some neurodegenerative diseases such as Parkinson, Alzheimer and etc.
Alizadeh, Akram., Beigi, Fatemeh., Ketabi, Majid., Mehdizadeh, Mehdi., Niknam Asl, Azadeh., Rigi, Sara., Sakhaei, Abolhassan., Soleimani, Mansooreh.   +7 more
core  

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Primary Coenzyme Q10 Deficiency [PDF]

, 2017
open4siCLINICAL CHARACTERISTICS: Primary coenzyme Q10 (CoQ10) deficiency is usually associated with multisystem involvement, including neurologic manifestations such as fatal neonatal encephalopathy with hypotonia; a late-onset slowly progressive ...
Doimo, Mara, Navas, P., Salviati, Leonardo, Trevisson, Eva   +3 more
core  

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

In silico analysis of Coenzyme Q10 interaction with the heme-hemoglobin complex: Implications for oxidative stress and inflammation in severe malaria

Advances in Biomarker Sciences and Technology
Background: Plasmodium falciparum, the primary causative agent of severe malaria, catabolizes hemoglobin to obtain nutrients, resulting in the accumulation of toxic free heme.
David B. Ouko, Fredrick M. Musila, Peris W. Amwayi, Victoria K. Mwaeni, Dickson B. Kinyanyi, Grace W. Gitau, Alfred Orina Isaac, James Nyabuga Nyariki   +7 more
doaj   +1 more source