Results 111 to 120 of about 86,596 (332)
Arthritis &Rheumatology, Accepted Article.Background Gout due to the formation of monosodium urate (MSU) crystals and calcium pyrophosphate (CPP) deposition disease are two major types of microcrystalline pathologies in adults. They are responsible for recurrent flares that rely on interleukin (IL)‐1β via activation of the NLRP3 inflammasome.
Chinh Nghia Pham +15 more
wiley +1 more source
Longevity of major coenzymes allows minimal de novo synthesis in microorganisms
Nature Microbiology, 2017 Johannes Hartl +3 more
semanticscholar +1 more source
YEAST ALCOHOL DEHYDROGENASE: MOLECULAR WEIGHT, COENZYME BINDING, AND REACTION EQUILIBRIA
, 1954 Joseph E. Hayes, Sidney F. Velick
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims To evaluate the effects of vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) oestrogen receptor degrader, on the pharmacokinetics of dabigatran (a P‐glycoprotein [P‐gp] substrate) and rosuvastatin (a breast cancer resistance protein [BCRP] substrate).
Derek Z. Yang +9 more
wiley +1 more source
Biomanufacturing Potential of Streamlined Cells
Biotechnology and Bioengineering, EarlyView.ABSTRACT A series of Escherichia coli streamlined strains was developed by removing the expression of genes encoding extracellular structures and unessential enzymes. The streamlined strains exhibited improved metabolic performance, including lower overflow metabolism and ATP maintenance coefficient, as well as a higher growth rate, compared to their ...
Alvaro R. Lara +10 more
wiley +1 more source
THE COENZYME CONTENT OF RABBIT MUSCLE d-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
, 1956 Jay B. Fox, Walter B. Dandliker
openalex +1 more source
Mechanism and role of regulated cell death in tumor immunity and immunotherapy
Cancer Communications, EarlyView.Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu +4 more
wiley +1 more source