Results 51 to 60 of about 2,155 (232)
Coformality around fibrations and cofibrations
Homology, Homotopy and Applications, 2023 We show that in a fibration the coformality of the base space implies the coformality of the total space under reasonable conditions, and these conditions can not be weakened. The result is partially dual to the classical work of Lupton \cite{Lup} on the formality within a fibration. Our result has two applications.
openaire +2 more sources
Trapping virtual pores by crystal retro-engineering [PDF]
, 2015 Stable guest-free porous molecular crystals are uncommon. By contrast, organic molecular crystals with guest-occupied cavities are frequently observed, but these cavities tend to be unstable and collapse on removal of the guests—this feature has been ...
AI Day +54 more
core +1 more source
Engineering and manufacturing of pharmaceutical co-crystals : a review on solvent-free manufacturing technologies [PDF]
, 2016 Design and synthesis of pharmaceutical cocrystals have received great interest in the recent years. Cocrystallization of drug substances offer a tremendous opportunity for the development of new drug products with superior physical and pharmacological ...
Douroumis, D. +2 more
core +1 more source
Cocrystal formation by Ionic liquid-assisted grinding: Case study with cocrystals of caffeine [PDF]
, 2018 iquid assisted grinding using imidazolium-based ionic liquids (IL-AG) was found to be effective in isolation of cocrystals and cocrystal polymorphs. Isolation of specific polymorphs of caffeine–citric acid (CAF–CA) and caffeine–glutaric acid (CAF–GLU ...
Meyerson, A. S. +2 more
core +1 more source
Impact of Mixed Solvent on Co-Crystal Solubility, Ternary Phase Diagram, and Crystallization Scale Up [PDF]
, 2016 This contribution covers the identification, understanding, and rationale of the interplay between the choice of mixed solvent on the crystallization of the co-crystal system benzoic acid and isonicotinamide (BZ:INA).
Blagden, Nicholas +4 more
core +1 more source
Pharmaceutical Cocrystal of Piroxicam: Design, Formulation and Evaluation [PDF]
Advanced Pharmaceutical Bulletin, 2017 Purpose: Cocrystallisation of drug with coformers is a promising approach to alter the solid sate properties of drug substances like solubility and dissolution.
Prabhakar Panzade +3 more
doaj +1 more source
Crystals, 2022 In this investigation, three new crystal forms of lidocaine, and another three of lidocaine hydrochloride with hydroquinone, resorcinol, and pyrogallol were synthetised.
Cristóbal Verdugo-Escamilla +5 more
doaj +1 more source
Coformer Replacement as an Indicator for Thermodynamic Instability of Cocrystals: Competitive Transformation of Caffeine:Dicarboxylic Acid [PDF]
, 2016 yesThe thermodynamic stability of caffeine (CA) cocrystals with dicarboxylic acids (DAs) as coformers was investigated in the presence of a range of structurally related dicarboxylic acids (SRDs).
Alsirawan, M.H.D. Bashir +4 more
core +3 more sources
Evaluation of synthon influence on ethenzamide– polyphenol pharmaceutical cocrystals [PDF]
, 2023 The pharmaceutical cocrystal landscape of ethenzamide has been addressed during the past years with the aim of improving its physicochemical properties, mainly solubility and dissolution rate. Herein four novel ethenzamide cocrystals have been isolated
Acebedo Martínez, Francisco Javier +5 more
core +1 more source
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2023 Cocrystallization is an emerging approach for improving physico-chemical characteristics of an active pharmaceutical ingredient (API) for instance dissolution rate, solubility, stability in addition to mechanical properties without affecting their ...
Ameera A Radhi +3 more
doaj +1 more source