Results 21 to 30 of about 147,127 (261)
Pupil dilation as cognitive load measure in instructional videos on complex chemical representations
Frontiers in Education, 2023 This secondary analysis of an earlier eye-tracking experiment investigated how triangulating changes in pupil dilation with student-self reports can be used as a measure of cognitive load during instructional videos with complex chemical representations.
Marc Rodemer +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Machine Learning and Knowledge ExtractionExplainable Artificial Intelligence (XAI) is a research area that clarifies AI decision-making processes to build user trust and promote responsible AI. Hence, a key scientific challenge in XAI is the development of methods that generate transparent and ...
Lucas Rizzo +3 more
doaj +1 more source
The evolution of cognitive load theory and its application to medical education
Perspectives on Medical Education, 2015 Cognitive Load Theory (CLT) has started to find more applications in medical education research. Unfortunately, misconceptions such as lower cognitive load always being beneficial to learning and the continued use of dated concepts and methods can result
Jimmie Leppink, Angelique van den Heuvel
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2009 Cognitive load theory is a learning and instruction theory that describes instructional design implications of human cognitive architecture outlined in the previous chapter. Based on these theoretically and empirically established instructional consequences (usually referred to as cognitive load effects or principles), the theory makes specific ...
Kirschner, Paul A. +2 more
+7 more sources
Frontiers in Artificial IntelligenceTime series classification is a challenging research area where machine learning and deep learning techniques have shown remarkable performance. However, often, these are seen as black boxes due to their minimal interpretability.
Ephrem Tibebe Mekonnen +4 more
doaj +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Computational Argumentation and Automatic Rule-Generation for Explainable Data-Driven Modeling
IEEE AccessThe creation of data-driven models for classification problems requires increasing transparency and inferential explainability, especially in high-stakes domains such as health-care, finance, and policy making. Rule-based systems are widely regarded as a
Luca Longo +3 more
doaj +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source