Results 101 to 110 of about 8,091 (213)

Classification of outcomes in antimalarial therapeutic efficacy studies with Aster. [PDF]

Antimicrob Agents Chemother
Gerlovina I, Berube S, Briggs J, Murie K, Murphy M, Wesolowski A, Greenhouse B.   +6 more
europepmc   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Leaf beetle diversity on a Southeast Asian continental island: Taxonomy, DNA barcoding, and preliminary evolutionary insights from Cat Ba Island, Vietnam. [PDF]

PLoS One
Nguyen DT, Ho LT.
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Phylogeography and Population Structure of the Invasive Land Snail <i>Monacha cartusiana</i>. [PDF]

Int J Mol Sci
Begum N, Noreen S, Badshah F, Ismail AM, Kanaan MHG, Ullah I, Alsabih AO, Almutairi S, Alabbad AF, Abdel-Maksoud MA, Kubra S, Rahman HU.   +11 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Opening the Discussion on the Costs of Pedophilic Disorder as a Mental Health Concern. [PDF]

Arch Sex Behav
Amelung T, Lehmann RJB, Schmidt AF, Hoyer A, Beier KM.   +4 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A closer look at the role of teacher emotional support, L2 grit, and burnout in foreign language achievement. [PDF]

BMC Psychol
Xie T, Chen M.
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source