Results 11 to 20 of about 7,720 (181)
SUMMARYColicins are proteins produced by and toxic for some strains ofEscherichia coli. They are produced by strains ofE. colicarrying a colicinogenic plasmid that bears the genetic determinants for colicin synthesis, immunity, and release. Insights gained into each fundamental aspect of their biology are presented: their synthesis, which is under SOS ...
Cascales, E. +8 more
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Phenotypic and Genotypic Profile of Enterobacteriaceae Isolated at a Teaching Hospital in Ghana. [PDF]
This study identified a significant prevalence of antimicrobial resistance determinants within Enterobacteriaceae isolates, with particular emphasis on those producing extended‐spectrum β‐lactamases (ESBL). These isolates harbored diverse antibiotic resistance genes (ARGs), plasmid replicons, and virulence factors (VFs), highlighting the imperative for
Donkor B +6 more
europepmc +2 more sources
Mechanism of export of colicin E1 and colicin E3 [PDF]
The mechanism of export of colicins E1 and E3 was examined. Neither colicin E1, colicin E3, Nor colicin E3 immunity protein appears to be synthesized as a precursor protein with an amino-terminal extension. Instead, the colicins, as well as the colicin E3 immunity protein, appear to leave the cells where they are made, long after their synthesis, by a ...
K S, Jakes, P, Model
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Mutational analysis of Cvab, an ABC transporter involved in the secretion of active colicin V. [PDF]
CvaB is the central membrane transporter of the colicin V secretion system that belongs to an ATP-binding cassette superfamily. Previous data showed that the N-terminal and C-terminal domains of CvaB are essential for the function of CvaB.
Kai-Hui Wu, Ying-Hsin Hsieh, Phang C Tai
doaj +1 more source
Colicin N Mediates Apoptosis and Suppresses Integrin-Modulated Survival in Human Lung Cancer Cells
The inherent limitations, including serious side-effects and drug resistance, of current chemotherapies necessitate the search for alternative treatments especially for lung cancer.
Wanatchaporn Arunmanee +6 more
doaj +1 more source
Sequencing Analysis of cvaC Gene in Acinetobacter Baumannii That Isolates from Different Infections [PDF]
Acinetobacter baumannii is one of the opportunistic nurses responsible for many acquired infections in hospitals due to its ability to resist many antibiotics. This is one of the problems facing hospitals in the world. Identification of the cvaC gene and
Rana Abdullah, Rasha Ahmed
doaj +1 more source
Screening and Molecular Dynamic Simulations of Colicin Produced by Commensals Escherichia coli Isolated from Animals [PDF]
E. coli strains isolated from animal feces were subjected to detection of colicin production. The produced colicin was prepared as a disc to serve as an inhibitor for other types of bacteria on Mueller-Hinton agar.
Amal F. Ghanim +3 more
doaj +1 more source
Optimizing Cell-Free Protein Synthesis for Increased Yield and Activity of Colicins
Colicins are antimicrobial proteins produced by Escherichia coli that hold great promise as viable complements or alternatives to antibiotics. Cell-free protein synthesis (CFPS) is a useful production platform for toxic proteins because it eliminates the
Xing Jin +2 more
doaj +1 more source
The objective of this work was to molecularly and genotypically characterize and test the inhibitory activity of six colicinogenic Escherichia coli strains (ColEc) and their partially purified colicins against STEC O157:H7 isolated from clinical human ...
Mauro D. García +5 more
doaj +1 more source
Toxin-antitoxin systems are genetic elements that are widespread in prokaryotes. Although molecular mode of action of many of these toxins has been identified, their biological functions are mostly unknown.
Wei-Lin Su +7 more
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