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Colistin Resistance and Management of Drug Resistant Infections
Canadian Journal of Infectious Diseases and Medical Microbiology, 2022 Colistin resistance is a globalized sensible issue because it has been considered a drug of the last-line resort to treat drug-resistant bacterial infections.
Juhi Sharma +3 more
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Prevalence, trends, and molecular insights into colistin resistance among gram-negative bacteria in Egypt: a systematic review and meta-analysis [PDF]
Annals of Clinical Microbiology and AntimicrobialsBackground This study examines colistin resistance in Gram-negative bacteria in Egypt, analyzing prevalence, trends, geographic variations, colistin-carbapenem resistance correlation, and mcr-mediated plasmid resistance. Methods We conducted a systematic
Ahmed Azzam +5 more
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An Evaluation of Alternative Treatment Strategies in Mitigating Colistin Resistance: Targeting Plasmid Transfer Through the Use of Bambermycin or the Protein Coded by the Mcr‐1 Gene With Antibodies and Streptomycin [PDF]
Veterinary Medicine and ScienceBackground Plasmid mediated antimicrobial resistance continues to be a source of global concern, especially given the limited pipeline of novel antibiotics.
Ibrahim Z. Hassan +2 more
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Frontiers in Microbiology, 2021 Colistin and tigecycline are the last options against carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP). Intersecting resistance determinants have been detected between these antibiotics; however, there is only limited evidence of such ...
Yawei Zhang +7 more
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Role of efflux pumps, their inhibitors, and regulators in colistin resistance
Frontiers in Microbiology, 2023 Colistin is highly promising against multidrug-resistant and extensively drug-resistant bacteria clinically. Bacteria are resistant to colistin mainly through mcr and chromosome-mediated lipopolysaccharide (LPS) synthesis-related locus variation. However,
Yinhuan Ding +9 more
doaj +1 more source
Journal of Global Antimicrobial Resistance, 2021 Background: Antimicrobial resistance to colistin, a widely used feed additive for farm animals across the world, has raised public health concern in recent years.
Masaru Usui +6 more
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Old drug, new findings: colistin resistance and dependence of [PDF]
Precision and Future Medicine, 2017 Colistin is an old drug, and its use has recently resurged because of increasing antibiotic resistance in gram-negative bacteria such as Acinetobacter baumannii.
Kwan Soo Ko, Yujin Choi, Ji-Young Lee
doaj +1 more source
Emerging Microbes and Infections, 2021 Infections caused by extensively drug-resistant (XDR) Acinetobacter nosocomialis have become a challenging problem. The frequent use of colistin as the last resort drug for XDR bacteria has led to the emergence of colistin-resistant A.
Ya-Sung Yang +10 more
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Asian Pacific Journal of Tropical Medicine, 2022 Objective: To find a proper method to assess colistin resistance in multidrug resistant Gram negative bacteria (MDR-GNB) on a routine basis in resource limited settings. Methods: Clinical samples were processed.
Shubham Chauhan +4 more
doaj +1 more source
A link between pH homeostasis and colistin resistance in bacteria
Scientific Reports, 2021 Colistin resistance is complex and multifactorial. DbcA is an inner membrane protein belonging to the DedA superfamily required for maintaining extreme colistin resistance of Burkholderia thailandensis. The molecular mechanisms behind this remain unclear.
Pradip R. Panta, William T. Doerrler
doaj +1 more source