Results 31 to 40 of about 1,026 (135)

The Distribution and Localization of Collagen Triple Helix Repeat Containing-1 in Naturally and Experimentally Avian Leukosis Virus Subgroup J-Infected Chickens

open access: yesFrontiers in Veterinary Science, 2020
Collagen triple helix repeat containing-1 (CTHRC1) has recently been identified as avian leukosis virus subgroup J (ALV-J) replication-dependent factor that remarkably facilitates ALV-J replication via interaction with the envelope glycoprotein (SU) of ...
Yu Pang   +5 more
doaj   +1 more source

CTHRC1 expression is a novel shared diagnostic and prognostic biomarker of survival in six different human cancer subtypes

open access: yesScientific Reports, 2021
According to the previous reports, the collagen triple helix repeat containing 1 (CTHRC1) causes tumorigenesis by modulating the tumor microenvironment, however, the evidence is limited to a few human cancer subtypes.
Nuzhat Sial   +16 more
doaj   +1 more source

The Role of CTHRC1 in Regulation of Multiple Signaling and Tumor Progression and Metastasis

open access: yesMediators of Inflammation, 2020
Collagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. CTHRC1 expresses mainly in adventitial fibroblasts and neointimal smooth muscle cells of balloon-injured vessels and promotes cell migration and tissue ...
Dan Mei   +3 more
doaj   +1 more source

Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1

open access: yesRespiratory Research, 2019
Background Pirfenidone, an antifibrotic agent used for the treatment of idiopathic pulmonary fibrosis (IPF), functions by inhibiting myofibroblast differentiation, which is involved in transforming growth factor (TGF)-β1-induced IPF pathogenesis. However,
Jin Jin   +17 more
doaj   +1 more source

CTHRC1 is a prognosis-related biomarker correlated with immune infiltrates in colon adenocarcinoma

open access: yesWorld Journal of Surgical Oncology, 2022
Background Colon adenocarcinoma (COAD) is one of the common cancers worldwide. Collagen triple helix repeat containing 1 (CTHRC1) has been reported to be involved in cell invasion, angiogenesis, and the promotion of epithelial-mesenchymal transformation ...
Chuang Meng   +3 more
doaj   +1 more source

Estimation levels of CTHRC1and some cytokines in Iraqi patients with Rheumatoid Arthritis

open access: yesمجلة بغداد للعلوم, 2023
Collagen triple helix repeat containing-1 (CTHRC1) is an essential marker for Rheumatoid Arthritis (RA), but its relationship with pro-inflammatory, anti-inflammatory, and inflammatory markers has been scantily covered in extant literature.
Ahmed R. Oleiwi, Ayaid Khadem Zgair
doaj   +1 more source

Collagen Triple Helix Repeat Containing-1 (CTHRC1) Expression in Invasive Ductal Carcinoma of the Breast: The Impact on Prognosis and Correlation to Clinicopathologic Features

open access: yesPathology & Oncology Research, 2013
CTHRC1 has been known as a regulator of collagen expression and cell migration. The aim of this research was to clarify the clinicopathologic significance of CTHRC1 expression in human breast cancer. 22 cases of breast cancer tissues, randomly selected from clinically diagnosed patients, showed a significant increase of CTHRC1 mRNA expression compared ...
Joo Heon, Kim   +9 more
openaire   +2 more sources

CTHRC1 Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Kidney Renal Papillary Cell Carcinoma and Kidney Renal Clear Cell Carcinoma

open access: yesFrontiers in Oncology, 2021
Kidney renal clear cell carcinoma (KIRC) and kidney renal papillary cell carcinoma (KIRP) are the most common RCC types. RCC has high immune infiltration levels, and immunotherapy is currently one of the most promising treatments for RCC. Collagen triple
Fenfang Zhou   +13 more
doaj   +1 more source

Cthrc1 is a positive regulator of osteoblastic bone formation. [PDF]

open access: yesPLoS ONE, 2008
Bone mass is maintained by continuous remodeling through repeated cycles of bone resorption by osteoclasts and bone formation by osteoblasts. This remodeling process is regulated by many systemic and local factors.We identified collagen triple helix ...
Hiroaki Kimura   +8 more
doaj   +1 more source

Value of serum collagen triple helix repeat containing-1(CTHRC1) and 14-3-3η protein compared to anti-CCP antibodies and anti-MCV antibodies in the diagnosis of rheumatoid arthritis

open access: yesBritish Journal of Biomedical Science, 2020
Serological markers are important in the diagnosis of rheumatoid arthritis (RA) and other connective tissues diseases This study explored the clinical value of collagen triple helix repeat containing-1 (CTHRC1) and 14-3-3η protein, compared to routine markers, in the diagnosis of RA.We recruited 103 RA patients, 105 non-RA patients (osteoarthritis ...
T Hu   +11 more
openaire   +2 more sources

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