Results 21 to 30 of about 7,134 (210)
Isolation and expression of a novel MBL-like collectin cDNA enhanced by LPS injection in the body wall of the ascidian Ciona intestinalis [PDF]
, 2009 Collectins are a family of calcium-dependent lectins that are characterized by their collagen-like domains. Considerable interest has been focused on this class of proteins because of their ability to interact with components of the complement system ...
Bonura, A. +5 more
core +1 more source
The Role of Humoral Innate Immunity in Hepatitis C Virus Infection
Viruses, 2012 Infection with Hepatitis C Virus (HCV) causes chronic disease in approximately 80% of cases, resulting in chronic inflammation and cirrhosis. Current treatments are not completely effective, and a vaccine has yet to be developed.
Richard A. Urbanowicz +2 more
doaj +1 more source
The carbohydrate recognition domain of collectins [PDF]
The FEBS Journal, 2011 Collectins are effector molecules of the innate immune system that play an important role in the first line of defence against bacteria, viruses and fungi. Most of their interactions with microorganisms are mediated through their carbohydrate recognition domain (CRD), which binds in a Ca2+‐dependent manner to glycoconjugates.
Veldhuizen, E.J.A. +2 more
openaire +4 more sources
Frontiers in Immunology, 2018 We conducted a prospective study of 312 patients (194 with multiple myeloma, 118 with lymphomas) receiving high-dose conditioning chemotherapy and autologous hematopoietic stem cell transplantation (auto-HSCT).
Anna S. Świerzko +20 more
doaj +1 more source
Pseudomonas aeruginosa elastase provides an escape from phagocytosis by degrading the pulmonary surfactant protein-A. [PDF]
PLoS ONE, 2011 Pseudomonas aeruginosa is an opportunistic pathogen that causes both acute pneumonitis in immunocompromised patients and chronic lung infections in individuals with cystic fibrosis and other bronchiectasis. Over 75% of clinical isolates of P.
Zhizhou Kuang +5 more
doaj +1 more source
Frontiers in Immunology, 2018 Influenza A viruses (IAVs) continue to pose major risks of morbidity and mortality during yearly epidemics and periodic pandemics. The genomic instability of IAV allows it to evade adaptive immune responses developed during prior infection. Of particular
I-Ni Hsieh +3 more
doaj +1 more source
Collectins, collectin receptors and the lectin pathway of complement activation
Clinical and Experimental Immunology, 1994 SummaryThe collectins are a group of soluble multimeric lectins, which contain collagenous segments, and resemble the complement protein Clq in aspects of their structures and functions. This group of proteins, which includes MBP, SP-A, SP-D, conglutinin and CL-43, are known to act as opsonins in various circumstances, and are likely to have roles in ...
R, Malhotra +3 more
openaire +3 more sources
Frontiers in Immunology, 2019 Innate immunity is critical in the early containment of influenza A virus (IAV) infection and surfactant protein D (SP-D) plays a crucial role in innate defense against IAV in the lungs.
Martin van Eijk +12 more
doaj +1 more source
Lectin complement protein Collectin 11 (CL-K1) and susceptibility to urinary schistosomiasis. [PDF]
PLoS Neglected Tropical Diseases, 2015 BACKGROUND:Urinary Schistosomiasis is a neglected tropical disease endemic in many sub Saharan -African countries. Collectin Kidney 1 (CL-K1, encoded by COLEC11 on chromosome 2p25.3), a member of the vertebrate C-type lectin super family, has recently ...
Justin S Antony +3 more
doaj +1 more source
Soluble Host Defense Lectins in Innate Immunity to Influenza Virus [PDF]
, 2012 Host defenses against viral infections depend on a complex interplay of innate (nonspecific) and adaptive (specific) components. In the early stages of infection, innate mechanisms represent the main line of host defense, acting to limit the spread of ...
Andrew G. Brooks +3 more
core +2 more sources