Results 31 to 40 of about 7,134 (210)

Comparative Signature-Tagged Mutagenesis Identifies Pseudomonas Factors Conferring Resistance to the Pulmonary Collectin SP-A. [PDF]

PLoS Pathogens, 2005
The pulmonary collectin, surfactant protein A (SP-A), is a broad spectrum opsonin with microbicidal membrane permeabilization properties that plays a role in the innate immune response of the lung.
Shiping Zhang, Yi Chen, Eric Potvin, Francois Sanschagrin, Roger C Levesque, Francis X McCormack, Gee W Lau   +6 more
doaj   +2 more sources

Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease.

PLoS Neglected Tropical Diseases, 2019
Chagas Disease (CD) is an anthropozoonosis caused by Trypanosoma cruzi. With complex pathophysiology and variable clinical presentation, CD outcome can be influenced by parasite persistence and the host immune response.
Thaisa Lucas Sandri, Fabiana Antunes Andrade, Kárita Cláudia Freitas Lidani, Elias Einig, Angelica Beate Winter Boldt, Benjamin Mordmüller, Meral Esen, Iara J Messias-Reason   +7 more
doaj   +1 more source

Role of collectin-11 in innate defence against uropathogenic infection

Innate Immunity, 2021
Classical collectins (surfactant protein A and D) play a significant role in innate immunity and host defence in uropathogenic Escherichia coli (UPEC)-induced urinary tract infection (UTI).
Hai Yuan, Zhao Gao, Xiaohan Lu, Fengqi Hu   +3 more
doaj   +1 more source

Association of Chlamydia pneumoniae with coronary artery disease and its progression is dependent on the modifying effect of mannose-binding lectin [PDF]

, 2002
Background— The possible association between coronary artery disease (CAD) and Chlamydia pneumoniae (C pneumoniae) infection is controversial. On the basis of the recent suggestion that mannose-binding lectin (MBL) variant alleles are related to an ...
Burián, Katalin, Duba, Jenő, Endrész, Valéria, Füst, György, Garred, Peter, Gönczöl, Éva, Karádi, István, Madsen, Hans O., Prohászka, Zoltán, Romics, László, Rugonfalvi-Kiss, Szabolcs   +10 more
core   +1 more source

S-nitrosylation of surfactant protein-D controls inflammatory function. [PDF]

PLoS Biology, 2008
The pulmonary collectins, surfactant proteins A and D (SP-A and SP-D) have been implicated in the regulation of the innate immune system within the lung. In particular, SP-D appears to have both pro- and anti-inflammatory signaling functions. At present,
Chang-Jiang Guo, Elena N Atochina-Vasserman, Elena Abramova, Joseph P Foley, Aisha Zaman, Erika Crouch, Michael F Beers, Rashmin C Savani, Andrew J Gow   +8 more
doaj   +1 more source

Frequency and distribution of FCN2 and FCN3 functional variants among MBL2 genotypes. [PDF]

, 2016
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Arnardottir, Margret, Bjarnadottir, Helga, Ludviksson, Bjorn Runar   +2 more
core   +1 more source

CL-L1 and CL-K1 Exhibit Widespread Tissue Distribution With High and Co-Localized Expression in Secretory Epithelia and Mucosa

Frontiers in Immunology, 2018
Collectin liver 1 (CL-L1, alias collectin 10) and collectin kidney 1 (CL-K1, alias collectin 11) are oligomeric pattern recognition molecules associated with the complement system, and mutations in either of their genes may lead to deficiency and ...
Soren W. K. Hansen, Josephine B. Aagaard, Karen B. Bjerrum, Eva K. Hejbøl, Ole Nielsen, Henrik D. Schrøder, Karsten Skjoedt, Anna L. Sørensen, Jonas H. Graversen, Maiken L. Henriksen   +9 more
doaj   +1 more source

Proteins of the Lectin Pathway of complement activation at the site of injury in subarachnoid hemorrhage compared with peripheral blood

Brain and Behavior, 2020
Background A subarachnoid hemorrhage (SAH) is a debilitating stroke. Activation of the lectin pathway (LP) of the complement system in SAH patients could worsen the prognosis; however, conflicting results have been reported.
Thorkil Anker‐Møller, Anne‐Mette Hvas, Niels Sunde, Steffen Thiel, Anne Troldborg   +4 more
doaj   +1 more source

Pentraxins in Complement Activation and Regulation

Frontiers in Immunology, 2018
The complement is the first line of immune defense system involved in elimination of invading pathogens and dying host cells. Its activation is mainly triggered by immune complexes or pattern recognition molecules (PRMs) upon recognition against non-self
Ying Jie Ma, Peter Garred
doaj   +1 more source

Collectin CL-LK Is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis. [PDF]

PLoS ONE, 2015
Understanding the molecular components of immune recognition of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, can help designing novel strategies to combat TB.
Anthony Troegeler, Geanncarlo Lugo-Villarino, Søren Hansen, Voahangy Rasolofo, Maiken Lumby Henriksen, Kenichiro Mori, Katsuki Ohtani, Carine Duval, Ingrid Mercier, Alan Bénard, Jérome Nigou, Denis Hudrisier, Nobutaka Wakamiya, Olivier Neyrolles   +13 more
doaj   +1 more source