Results 51 to 60 of about 7,134 (210)

Arg343 in Human Surfactant Protein D Governs Discrimination between Glucose and N-Acetylglucosamine Ligands [PDF]

, 2004
Surfactant protein D (SP-D), one of the members of the collectin family of C-type lectins, is an important component of pulmonary innate immunity. SP-D binds carbohydrates in a calcium-dependent manner, but the mechanisms governing its ligand recognition
Allen, Martin, Laederach, Alain, Mason, Robert, Reilly, Peter, Reilly, Peter, Voelker, Dennis   +5 more
core   +3 more sources

The Impact of Surfactant Protein‐D Gene Polymorphism on COVID‐19 Clinical Outcomes

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background COVID‐19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), presents a broad spectrum of clinical manifestations, ranging from asymptomatic cases to severe, life‐threatening respiratory complications. Pulmonary surfactant‐associated protein D (SP‐D) is a critical component of pulmonary immune defense.
Nadia Nasirzadeh Kolsari, Azarakhsh Azaran, Roya Pirmoradi, Maryam Moradi, Roohangiz Nashibi, Shahram Jalilian   +5 more
wiley   +1 more source

Role of mannose-binding lectin in the innate defense against Candida albicans: Enhancement of complement activation, but lack of opsonic function, in phagocytosis by human dendritic cells [PDF]

, 2004
Mannose-binding lectin (MBL) is a serum collectin believed to be of importance in innate immunity. We have investigated the role of MBL in the first-line defense against Candida albicans, an opportunistic fungal pathogen. MBL bound C.
Ip, WK, Lau, YL
core   +1 more source

3D‐printing of Methacryloylated Recombinant Collagen for Tissue Engineering

ChemistrySelect, Volume 11, Issue 17, 5 May 2026.
Recombinant collagen‐like proteins offer promise as alternatives to mammalian collagens. There is less risk of disease transfer, and changes in structure can be readily introduced. Here, a recombinant collagen‐like protein was methacryloylated for extrusion printing and rapid photo‐crosslinking.
Malachy K. Maher, Veronica Glattauer, Zhilian Yue, Timothy C. Hughes, Carmine Onofrillo, Serena Duchi, John A. M. Ramshaw, Gordon G. Wallace   +7 more
wiley   +1 more source

Surfactant Protein-D Is Essential for Immunity to Helminth Infection.

PLoS Pathogens, 2016
Pulmonary epithelial cell responses can enhance type 2 immunity and contribute to control of nematode infections. An important epithelial product is the collectin Surfactant Protein D (SP-D).
Sumaiyya Thawer, Jennifer Auret, Corinna Schnoeller, Alisha Chetty, Katherine Smith, Matthew Darby, Luke Roberts, Rosie-Marie Mackay, Harry J Whitwell, John F Timms, Jens Madsen, Murray E Selkirk, Frank Brombacher, Howard William Clark, William G C Horsnell   +14 more
doaj   +1 more source

Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement

eLife, 2020
Properdin stabilizes the alternative C3 convertase (C3bBb), whereas its role as pattern-recognition molecule mediating complement activation is disputed for decades.
Jie Zhang, Lihong Song, Dennis V Pedersen, Anna Li, John D Lambris, Gregers Rom Andersen, Tom Eirik Mollnes, Ying Jie Ma, Peter Garred   +8 more
doaj   +1 more source

Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H., Mitchell, Daniel A., Schmid, Ralf, Schwaeble, Wilhelm J., Wallis, Russell   +4 more
core   +1 more source

Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin-Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H-Related Protein-5 (FHR5) Deposition

, 2017
Introduction IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-deficient IgA1 and complement proteins and leads to renal impairment.
Constantinou, N, Cook, HT, Hansen, AG, Lomax-Browne, HJ, Medjeral-Thomas, NR, Pickering, MC, Pusey, CD, Thiel, S, Troldborg, A, Willicombe, M   +9 more
core   +2 more sources

Proteomic Profiling of Human Extracellular Vesicles Reveals Diagnostic Biomarkers for Colon Adenocarcinoma

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
Proteomic profiling of tissue explant‐ and plasma‐derived extracellular vesicles identified colon adenocarcinoma‐associated and healthy‐associated EV proteins. A 10‐protein EV panel enabled highly sensitive blood‐based detection of colon adenocarcinoma, showed marked postoperative changes, and retained performance in an independent validation cohort ...
Yura Seo, Yoon Dae Han, Linda Bojmar, Kyung‐A Kim, Yurin Seo, Taeyul K. Kim, Suho Lee, Yeleem Kim, Hye Bin Choi, Yujin H. Lim, Chae Hyun Kim, Alexander Sandberg, Chuanwen Fan, Pernille Lauritzen, Henrik Molina, Christopher Peralta, Jacob B. Geri, Colin Burdette, Dai Hoon Han, Heon Yung Gee, Insuk Lee, Jeon‐Soo Shin, Hyunwook Kim, Leon Li, Gabriel C. Tobias, Inbal Wortzel, Sang Joon Shin, Hyo‐Il Jung, Min Goo Lee, Soonmyung Paik, Robert E. Schwartz, Joong Bae Ahn, David Lyden, Han Sang Kim   +33 more
wiley   +1 more source

PENGEMBANGAN MODUL FISIKA BERBASIS DISCOVERY LEARNING DENGAN PENDEKATAN PROBLEM BASED LEARNING UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS DAN KREATIF SISWA KELAS XI SMA/MA DI SURAKARTA [PDF]

, 2016
Penelitian dan pengembangan ini bertujuan untuk: 1) mengembangkan modul pembelajaran Fisika berbasis Discovery Learning dengan pendekatan Problem Based Learning (PBL) untuk meningkatkan kemampuan berpikir kritis dan kreatif siswa, 2) mengetahui kelayakan
Adi, Delisma Wisnu
core