Results 71 to 80 of about 7,134 (210)

Mathematical modeling predicts novel mechanisms of stream confinement from Trail/Colec12/Dan in the collective migration of cranial neural crest cells

Developmental Dynamics, Volume 255, Issue 1, Page 43-65, January 2026.
Abstract Background In vertebrate embryogenesis, cranial neural crest cells (CNCCs) migrate along discrete pathways. Analyses in the chick have identified key molecular candidates for the confinement of CNCC migration to stereotypical pathways as Colec12, Trail, and Dan.
Samuel W. S. Johnson, Paul M. Kulesa, Ruth E. Baker, Philip K. Maini   +3 more
wiley   +1 more source

Rapid and Efficient Purification of Functional Collectin-12 and Its Opsonic Activity against Fungal Pathogens

Journal of Immunology Research, 2019
Collectin-12 (collectin placenta 1, CL-P1, or CL-12) is a newly identified pattern recognition molecule of the innate immune system. Recent evidences show that CL-12 plays important roles not only in innate immune protection against certain clinically ...
Jie Zhang, Anna Li, Chang-qing Yang, Peter Garred, Ying Jie Ma   +4 more
doaj   +1 more source

CLEC5A-mediated enhancement of the inflammatory response in myeloid cells contributes to influenza virus pathogenicity in vivo [PDF]

, 2017
Human infections with influenza viruses exhibit mild to severe clinical outcomes as a result of complex virus-host interactions. Induction of inflammatory mediators via pattern recognition receptors may dictate subsequent host responses for pathogen ...
Bruzzone, R, Chen, ST, Cole, SL, Doak, SA, Hsieh, SAL, Hsu, TL, Hsu, TY, Peiris, JSM, Sia, SF, Teng, O, Tu, W, Yen, H, Zheng, JT   +12 more
core   +1 more source

Proteomic Biomarkers Are Linked to QTc Interval in Patients With Chronic Heart Failure

PROTEOMICS – Clinical Applications, Volume 20, Issue 1, January 2026.
ABSTRACT Objective This study investigates the link between circulating proteins and rate‐corrected QT (QTc) interval in patients with heart failure with reduced ejection fraction (HFrEF) and their association with cardiovascular outcomes. Methods and Results We analyzed 197 HFrEF patients from the prospective Serial Biomarker Measurements and New ...
Mylène Barry‐Loncq de Jong, Teun B. Petersen, Sabrina Abou Kamar, Navin Suthahar, Nick van Boven, K. Martijn Akkerhuis, Peter J. van der Spek, Peter D. Katsikis, Rudolf A. de Boer, Victor A. W. M. Umans, Eric Boersma, Folkert W. Asselbergs, Jasper J. Brugts, Sing‐Chien Yap, Isabella Kardys   +14 more
wiley   +1 more source

Assessment of Surfactant Protein A (SP-A) dependent agglutination [PDF]

, 2010
Background: Monomers of the collectin surfactant associated protein-A (SP-A) are arranged in trimers and higher oligomers. The state of oligomerization differs between individuals and likely affects SP-A's functional properties.
Stefanie M Heinrich, Matthias Griese
core   +3 more sources

Structural Characterization of Bovine Collectin‐43 [PDF]

European Journal of Biochemistry, 1997
Bovine collectin‐43 (CL‐43), the most recently disclosed member of the collectin group, has been characterized structurally at the protein level by a combination of mass spectrometry and protein sequencing. The molecular mass of reduced CL‐43 was determined by the use of mass spectrometry to be 33.6±0.1 kDa.
A B, Rothmann, H D, Mortensen, U, Holmskov, P, Højrup   +3 more
openaire   +2 more sources

Multi‐omics analysis of gut‐organ axes reveals the high‐altitude adaptation in Tibetan chicken

iMetaOmics, Volume 2, Issue 3, September 2025.
The Qinghai‐Tibet Plateau is an extreme ecosystem subject to special climatic conditions that require unique adaptations for its inhabiting organisms. In addition to genetic characteristics, the gut microbiota of animals can regulate the environmental adaptation of their hosts through various gut–organ axes.
Tao Zeng, Tiantian Gu, Yongqing Cao, Yong Tian, Jianmei Yin, Peishi Feng, Hanxue Sun, Jindong Ren, Xueying Ma, Zelong Zhao, Guohui Li, Li Chen, Wenwu Xu, Qian Xue, Wei Han, Lizhi Lu   +15 more
wiley   +1 more source

Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection [PDF]

, 2010
BACKGROUND: Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, inhibits influenza A virus infection in vitro. MBL deficiency due to gene polymorphism in humans has been associated with infection susceptibility.
Kazue Takahashi, Kevan L Hartshorn, Mitchell R White, Patience Moyo, Sheree McClear, Steffen Thiel, Wei-Chuan Chang   +6 more
core   +5 more sources

Chimerolectins: Classification, structural architecture, and functional perspectives

Protein Science, Volume 34, Issue 9, September 2025.
Abstract Lectins are proteins or glycoproteins capable of binding specifically and reversibly to carbohydrates, a property that, in itself, gives them great functional versatility in organisms from all kingdoms of nature. A subclass of these proteins, called chimerolectins, is composed of proteins that have at least one lectin domain associated with ...
Vanir Reis Pinto‐Junior, Benildo Sousa Cavada, Kyria Santiago Nascimento   +2 more
wiley   +1 more source

Complement and transplant‐associated thrombotic microangiopathy: Current and future approaches

HemaSphere, Volume 10, Issue 4, April 2026.
Massimo Cugno, Francesco Onida, Bernhard Lämmle   +2 more
wiley   +1 more source