Results 151 to 160 of about 5,247 (206)

Pattern recognition receptors: function, regulation and therapeutic potential. [PDF]

open access: yesSignal Transduct Target Ther
Chen R   +5 more
europepmc   +1 more source

Idiopathic Pulmonary Fibrosis: A Comprehensive Review of Risk Factors, Genetics, Diagnosis, and Therapeutic Approaches. [PDF]

open access: yesBiomedicines
Senhaji L   +9 more
europepmc   +1 more source

The collectins in innate immunity

Current Opinion in Immunology, 1996
The collectins are proteins with collagen tails and globular lectin domains that appear to play an important role in mammalian first line host defense. Recent insights have clarified the structural basis of ligand recognition, the interactions of collectins with complement cascades, and the association with disease susceptibility.
J, Epstein   +3 more
exaly   +3 more sources

Collectins and innate immunity in the lung

Microbes and Infection, 2000
Evidence from both in vitro and in vivo studies suggests that the collectins are important elements in host innate immune defences against infectious agents. Study of the collectins in specific disease settings now raises the prospects of developing therapies exploiting these mechanisms of innate immunity.
Howard W Clark, Robert B Sim
exaly   +3 more sources

Collectins and Pulmonary Host Defense

American Journal of Respiratory Cell and Molecular Biology, 1998
Abstract The surfactant-associated proteins SP-A and SP-D are members of a family of collagenous host defense lectins, designated collectins. There is increasing evidence that these pulmonary epithelial-derived proteins are important components of the innate immune response to microbial challenge, and that they participate in other ...
exaly   +3 more sources

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