Pattern recognition receptors: function, regulation and therapeutic potential. [PDF]
Chen R +5 more
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The Interactions of the Complement System with Human Cytomegalovirus. [PDF]
Lujan E, Zhang I, Garon AC, Liu F.
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Congenital Human Cytomegalovirus and the Complement System. [PDF]
Garon AC, Liu Y, Liu F.
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Immunomodulatory functions of fungal melanins in respiratory infections. [PDF]
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Chicken surfactant protein A1 activates macrophages phagocytosis and attenuates LPS-induced inflammatory response through the TLR4-mediated NF-кB pathway. [PDF]
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Polymorphisms in Immune Genes and Their Association with Tuberculosis Susceptibility: An Analysis of the African Population. [PDF]
Wodelo W +4 more
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Idiopathic Pulmonary Fibrosis: A Comprehensive Review of Risk Factors, Genetics, Diagnosis, and Therapeutic Approaches. [PDF]
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The collectins in innate immunity
Current Opinion in Immunology, 1996The collectins are proteins with collagen tails and globular lectin domains that appear to play an important role in mammalian first line host defense. Recent insights have clarified the structural basis of ligand recognition, the interactions of collectins with complement cascades, and the association with disease susceptibility.
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Collectins and innate immunity in the lung
Microbes and Infection, 2000Evidence from both in vitro and in vivo studies suggests that the collectins are important elements in host innate immune defences against infectious agents. Study of the collectins in specific disease settings now raises the prospects of developing therapies exploiting these mechanisms of innate immunity.
Howard W Clark, Robert B Sim
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Collectins and Pulmonary Host Defense
American Journal of Respiratory Cell and Molecular Biology, 1998Abstract The surfactant-associated proteins SP-A and SP-D are members of a family of collagenous host defense lectins, designated collectins. There is increasing evidence that these pulmonary epithelial-derived proteins are important components of the innate immune response to microbial challenge, and that they participate in other ...
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